ID A8XVB6_CAEBR Unreviewed; 946 AA.
AC A8XVB6;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 15-JAN-2008, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE SubName: Full=Protein CBR-EHBP-1 {ECO:0000313|EMBL:CAP36583.1};
GN Name=ehbp-1 {ECO:0000313|WormBase:CBG19308};
GN Synonyms=Cbr-ehbp-1 {ECO:0000313|EMBL:CAP36583.1};
GN ORFNames=CBG19308 {ECO:0000313|WormBase:CBG19308}, CBG_19308
GN {ECO:0000313|EMBL:CAP36583.1};
OS Caenorhabditis briggsae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6238 {ECO:0000313|EMBL:CAP36583.1, ECO:0000313|Proteomes:UP000008549};
RN [1] {ECO:0000313|EMBL:CAP36583.1, ECO:0000313|Proteomes:UP000008549}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF16 {ECO:0000313|EMBL:CAP36583.1,
RC ECO:0000313|Proteomes:UP000008549};
RX PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA Fitch D.H., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA Durbin R., Waterston R.H.;
RT "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT genomics.";
RL PLoS Biol. 1:166-192(2003).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; HE601047; CAP36583.1; -; Genomic_DNA.
DR RefSeq; XP_002637575.1; XM_002637529.1.
DR AlphaFoldDB; A8XVB6; -.
DR STRING; 6238.A8XVB6; -.
DR GeneID; 8579570; -.
DR KEGG; cbr:CBG_19308; -.
DR CTD; 8579570; -.
DR WormBase; CBG19308; CBP39557; WBGene00038554; Cbr-ehbp-1.
DR eggNOG; KOG0035; Eukaryota.
DR HOGENOM; CLU_020232_0_0_1; -.
DR InParanoid; A8XVB6; -.
DR OMA; DPNDTPH; -.
DR OrthoDB; 2881296at2759; -.
DR Proteomes; UP000008549; Unassembled WGS sequence.
DR GO; GO:0031941; C:filamentous actin; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005815; C:microtubule organizing center; IBA:GO_Central.
DR GO; GO:0030036; P:actin cytoskeleton organization; IBA:GO_Central.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR InterPro; IPR022735; bMERB_dom.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR019448; NT-C2.
DR PANTHER; PTHR23167; CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED; 1.
DR PANTHER; PTHR23167:SF87; EH (EPS-15-HOMOLOGY) DOMAIN BINDING PROTEIN FAMILY; 1.
DR Pfam; PF12130; bMERB_dom; 1.
DR Pfam; PF00307; CH; 1.
DR Pfam; PF10358; NT-C2; 1.
DR SMART; SM00033; CH; 1.
DR SMART; SM01203; DUF3585; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR PROSITE; PS51840; C2_NT; 1.
DR PROSITE; PS50021; CH; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008549};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 679..700
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 8..161
FT /note="C2 NT-type"
FT /evidence="ECO:0000259|PROSITE:PS51840"
FT DOMAIN 342..449
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT REGION 218..342
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 502..646
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 218..252
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 307..329
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 536..559
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 560..576
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 590..607
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 609..631
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 946 AA; 107276 MW; C4786E2B914BE6A0 CRC64;
MANILRRLRR SSKKAAKFRF TVTLQELQLY TDEKWKPENL VVSFVHRRRK VSSKERRWEQ
SYSDVNKCVI MWPEQMTENV DILTTLYRTP DDDTFEDKEW TIVIEELTAK GKRKAIAAVP
INVRLFILDL PEHKSELKLK LRPLSPHLKM CSLIILLGST LISEVSGDDV SVSSSAAASF
VEKVPVPEDE VDASVRDPRT AAAIQQIDST ATKIKEWANE KKEASPAVPA HRKPSEESGE
LAKIRPQWRV SAEEEKSSQQ ASAPTPTAPA APIATNRHSR SSRASTEEKT ATTTEFRVDS
YSRPVPVATP ISATPSYLQS GSMHRGRSNS PRAPSRDAVP QPVSGETLLS WCQRVTNGYS
HVKINDFTKS WKNGLGLCAI LHTYHPELIG DYESLDISNN MSGQKENVQK ALDAMSMMGL
TDIPTVDMFI TPDRKQIELL LQRLRRVFEG CEDGSTPASA SDHRISRTFG MTETEEKVVA
MIAELRNKKD LEDAVDYTNI PDQVEAPVTP QLASRNPALN QPIDDDDDDA ETSNMRFERS
NVSITMVTPG VGTIRASNRA SPSKRDELRQ RAREMLEKST TNQSATPNSR KGSDEERRRE
EVRRLLNEKQ STAIPSTSSS PYPTFRRING SNTDLRRIDD PNDTPHVPAI GRRTNGNRVN
CLSNVYQDKT SNFQSHRHIS FSSLFFFLFS ITIVFILYML CSSSRVVLTL QNDPATPSTF
DRVKRYGSMR SAELKESLQL MAKQYGYMGN DYELSSQDAP ATPSKKFSSQ WEKDVDDVEG
TAQELVRIDE RISDITRQAE SIQDKIRETE VGSSEEEMLT ASYLQLTNER NTLVHRQEYY
NIIETIRPTI AEIEDLTRQI DEITQIADDF PRSDENKRAT DKLMEEYSNA MKTKSNLVRK
LFATEEEIEE DSDRLKNLTL DRATRFVRGI DQPVSASKRL IQWWRR
//
