ID A8XY86_CAEBR Unreviewed; 505 AA.
AC A8XY86;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 15-JAN-2008, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE SubName: Full=Protein CBG20626 {ECO:0000313|EMBL:CAP37603.1};
GN Name=acs-11 {ECO:0000313|WormBase:CBG20626};
GN ORFNames=CBG20626 {ECO:0000313|EMBL:CAP37603.1,
GN ECO:0000313|WormBase:CBG20626}, CBG_20626
GN {ECO:0000313|EMBL:CAP37603.1};
OS Caenorhabditis briggsae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6238 {ECO:0000313|EMBL:CAP37603.1, ECO:0000313|Proteomes:UP000008549};
RN [1] {ECO:0000313|EMBL:CAP37603.1, ECO:0000313|Proteomes:UP000008549}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF16 {ECO:0000313|EMBL:CAP37603.1,
RC ECO:0000313|Proteomes:UP000008549};
RX PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA Fitch D.H., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA Durbin R., Waterston R.H.;
RT "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT genomics.";
RL PLoS Biol. 1:166-192(2003).
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
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DR EMBL; HE600991; CAP37603.1; -; Genomic_DNA.
DR RefSeq; XP_002631472.1; XM_002631426.1.
DR AlphaFoldDB; A8XY86; -.
DR STRING; 6238.A8XY86; -.
DR EnsemblMetazoa; CBG20626.1; CBG20626.1; WBGene00039574.
DR GeneID; 8573470; -.
DR KEGG; cbr:CBG_20626; -.
DR CTD; 8573470; -.
DR WormBase; CBG20626; CBP19968; WBGene00039574; Cbr-acs-11.
DR eggNOG; KOG1176; Eukaryota.
DR HOGENOM; CLU_000022_59_0_1; -.
DR InParanoid; A8XY86; -.
DR OMA; YKIPQEM; -.
DR OrthoDB; 5473537at2759; -.
DR Proteomes; UP000008549; Unassembled WGS sequence.
DR GO; GO:0031956; F:medium-chain fatty acid-CoA ligase activity; IBA:GO_Central.
DR GO; GO:0006631; P:fatty acid metabolic process; IBA:GO_Central.
DR CDD; cd05941; MCS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43201; ACYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR43201:SF8; FATTY ACID COA SYNTHETASE FAMILY; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008549}.
FT DOMAIN 29..354
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 412..487
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 505 AA; 55519 MW; FC48D639ECF045E1 CRC64;
MLSRLVGSIP QRVGIRAASS ASNNIVSQAQ IQAEPSKILF IDGEHKTTYA EFVKRAGQYA
TALTEKYNIK KGDRVMARVS KTTDTAALYI ACLQIGALYI PVNPGYTESE AAHYIKDATP
SLLVTCNEDL DQVFRDRISV LNENKLASEA GSLNACTTIE HVETSDPASV CYTSGTTGLP
KGAILTHGSL SNNAHDIVRD WGFTSEDLNL HALPFYHVHG LYYSLHCSLF SHSTIIWRSK
FEVEDCIKYM KNATVMMGVP TFFSRLLASK NFKKDAFGNV RVFISGSAPL SVATIEEFKE
RTGQVILERY GMTEAGVMTT NPLNGVRKAG TVGPAVKGVG CRIAKNGGIE VKTNAIFAGY
WKNPKKTAEE FTEDGWFKTG DVGHLDEDGY LTIGGRSKDM IITGGLNVYP KELEDFIDTL
PFVKESAVIA SPHPDFGEAV VAVVVPAEKV TDEKEFEKKL IGIMKKKVAN YKVPKRVIIL
DSLPRNHITK VQKNVLRDNY KKLFA
//
