ID A8XZL0_CAEBR Unreviewed; 1249 AA.
AC A8XZL0;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 2.
DT 27-MAR-2024, entry version 99.
DE SubName: Full=Protein CBG21212 {ECO:0000313|EMBL:CAP38009.2};
GN Name=myo-6 {ECO:0000313|WormBase:CBG21212};
GN ORFNames=CBG21212 {ECO:0000313|EMBL:CAP38009.2,
GN ECO:0000313|WormBase:CBG21212}, CBG_21212
GN {ECO:0000313|EMBL:CAP38009.2};
OS Caenorhabditis briggsae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6238 {ECO:0000313|EMBL:CAP38009.2, ECO:0000313|Proteomes:UP000008549};
RN [1] {ECO:0000313|EMBL:CAP38009.2, ECO:0000313|Proteomes:UP000008549}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF16 {ECO:0000313|EMBL:CAP38009.2,
RC ECO:0000313|Proteomes:UP000008549};
RX PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA Fitch D.H., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA Durbin R., Waterston R.H.;
RT "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT genomics.";
RL PLoS Biol. 1:166-192(2003).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, myofibril
CC {ECO:0000256|ARBA:ARBA00004657}.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR EMBL; HE600921; CAP38009.2; -; Genomic_DNA.
DR AlphaFoldDB; A8XZL0; -.
DR STRING; 6238.A8XZL0; -.
DR WormBase; CBG21212; CBP11705; WBGene00040055; Cbr-myo-6.
DR eggNOG; KOG0161; Eukaryota.
DR HOGENOM; CLU_000192_7_2_1; -.
DR InParanoid; A8XZL0; -.
DR OMA; KERRMQM; -.
DR OrthoDB; 640507at2759; -.
DR Proteomes; UP000008549; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0030016; C:myofibril; IEA:UniProtKB-SubCell.
DR GO; GO:0032982; C:myosin filament; IBA:GO_Central.
DR GO; GO:0016460; C:myosin II complex; IBA:GO_Central.
DR GO; GO:0051015; F:actin filament binding; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000146; F:microfilament motor activity; IBA:GO_Central.
DR GO; GO:0006936; P:muscle contraction; IBA:GO_Central.
DR GO; GO:0045214; P:sarcomere organization; IBA:GO_Central.
DR CDD; cd01377; MYSc_class_II; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 6.20.240.20; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 2.30.30.360; Myosin S1 fragment, N-terminal; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR Gene3D; 4.10.270.10; Myosin, subunit A; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR004009; Myosin_N.
DR InterPro; IPR008989; Myosin_S1_N.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR45615; MYOSIN HEAVY CHAIN, NON-MUSCLE; 1.
DR PANTHER; PTHR45615:SF58; MYOSIN-4; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF02736; Myosin_N; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF90257; Myosin rod fragments; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50096; IQ; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51844; SH3_LIKE; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Coiled coil {ECO:0000256|SAM:Coils};
KW Methylation {ECO:0000256|ARBA:ARBA00022481};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Muscle protein {ECO:0000256|ARBA:ARBA00023179};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000008549};
KW Thick filament {ECO:0000256|ARBA:ARBA00022433}.
FT DOMAIN 32..82
FT /note="Myosin N-terminal SH3-like"
FT /evidence="ECO:0000259|PROSITE:PS51844"
FT DOMAIN 86..795
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 671..693
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT COILED 859..1076
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1105..1160
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 195..202
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1249 AA; 144551 MW; 17474FB24AD68971 CRC64;
MANIDYMMDP GWKYLRQAQD EALKEQAARR FDNKTHAWVP DAAEGFVAAA IAVQEGDNLT
LTMPSDGSQK RLTRSEVQEI NPAKFEKTED MSNLTFLNEA SVLHNLRQRY YSMMIYTYSG
LFCVFINPYK MLPIYTDSVA SMYVNKRRAE MPPHLFAVSD EAFRNMMSGR SLELLHFQIF
LKFSDKENQS MLITGESGAG KTENTKKVIA YFAMIGSGNK DQKSESSLEN QVVQANPAIE
AFGNGATTRN YNSSRYGKFI RIHFDRKGRL VGGDIEHYLL EKSRVIKQAP GERSYHIFYQ
IMTQKALRGN DNIRDYKFVS QAEITVPGMN DTEEWGITDT AFNVMGFSER EKDDLYKLCS
AIMHIGNSTF KQKPRDEQAE VDDMKSPTAA CKLFGIDTDQ FLNALTRPRI KVGMEWVNKG
QNVQQVDWAV GALSKAIYAR MFHWLIKRVN KTLQANSDDM VYYIGVLDIA GFEIFDRNSF
EQLWINFVNE KLQQFFNHHM FVLEQEEYQR EGIEWTFIDF GLDLQSCIEL IEKPLGIVSM
LDEECIVPKA TDMTYVDKLL TQHLGKHPNF QKAKPPKGKQ ADAHFAIVHY AGTVRYNAEQ
WLDKNKDPLN DSAVAILKTS DKEGVLYQLW EDYQTDVDRE ESEKRGKTTQ AKKKGKSASF
LTVSTMYRES LTSLMTMLHT THPHFIRCII PNEKKTSGLI DAPLVLNQLT CNGVLEGIRI
CRKGFPNRMM FADFRFRYAI LAADEASEKD AAKASKAMLR KLSKSNQLNV DTFKVGTTKI
FFKAGMLARL EELRDEALSA VILKFQCSAR HYLAQVEYKR RLDREDAYPI IQENVRAWIK
LRSWPWYRLF SRLKPMLKGM KSNAEIEALE KKCKELEENH KREEEARKKY ADELRAKIDQ
YEETKAALER DRMLLDKRNK EIEELNRNLK AESESNYENA KKAAELEKLR EKERKEWDEK
ERRMQMEAEN ETNQHKTQTE KLKDQIASMQ TDYDKLSAQR KAQEQMNAEL VDEVALLKNK
AERAEEQKKK LVEDLDAMDD KLAAEKRANN EHVKHNKKLE ASLKATQTQL TLALKEKHEN
DVDCKRRESE IGELKLKAQG DANLISKLQA MLRRCISRIE ELEEDLLEER KLRMKAERQF
NELRSEFDVL TEQMAEASGQ LTAEAHINKV RAEEVSMLRR DLQKRNLNHE AYISDLCNMQ
YATVNNLRNL SQQSSALETE ALRILDHRRA ISKQPLPRVY VEDPDSDLE
//
