ID A8Y4A1_CAEBR Unreviewed; 438 AA.
AC A8Y4A1;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 15-JAN-2008, sequence version 1.
DT 27-MAR-2024, entry version 96.
DE SubName: Full=Protein CBR-CEH-32 {ECO:0000313|EMBL:CAP39721.1};
GN Name=ceh-32 {ECO:0000313|WormBase:CBG23282};
GN Synonyms=Cbr-ceh-32 {ECO:0000313|EMBL:CAP39721.1};
GN ORFNames=CBG23282 {ECO:0000313|WormBase:CBG23282}, CBG_23282
GN {ECO:0000313|EMBL:CAP39721.1};
OS Caenorhabditis briggsae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6238 {ECO:0000313|EMBL:CAP39721.1, ECO:0000313|Proteomes:UP000008549};
RN [1] {ECO:0000313|EMBL:CAP39721.1, ECO:0000313|Proteomes:UP000008549}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF16 {ECO:0000313|EMBL:CAP39721.1,
RC ECO:0000313|Proteomes:UP000008549};
RX PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA Fitch D.H., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA Durbin R., Waterston R.H.;
RT "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT genomics.";
RL PLoS Biol. 1:166-192(2003).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
CC ECO:0000256|RuleBase:RU000682}.
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DR EMBL; HE601533; CAP39721.1; -; Genomic_DNA.
DR RefSeq; XP_002636588.1; XM_002636542.1.
DR AlphaFoldDB; A8Y4A1; -.
DR STRING; 6238.A8Y4A1; -.
DR EnsemblMetazoa; CBG23282.1; CBG23282.1; WBGene00041666.
DR GeneID; 8578583; -.
DR KEGG; cbr:CBG_23282; -.
DR CTD; 8578583; -.
DR WormBase; CBG23282; CBP05544; WBGene00041666; Cbr-ceh-32.
DR eggNOG; KOG0775; Eukaryota.
DR HOGENOM; CLU_049495_0_0_1; -.
DR InParanoid; A8Y4A1; -.
DR OMA; EMWHEAH; -.
DR OrthoDB; 602349at2759; -.
DR Proteomes; UP000008549; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0005667; C:transcription regulator complex; IBA:GO_Central.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0009886; P:post-embryonic animal morphogenesis; IEA:EnsemblMetazoa.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR031701; SIX1_SD.
DR PANTHER; PTHR10390; HOMEOBOX PROTEIN SIX; 1.
DR PANTHER; PTHR10390:SF33; PROTEIN OPTIX; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR Pfam; PF16878; SIX1_SD; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000256|RuleBase:RU000682};
KW Homeobox {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000256|RuleBase:RU000682};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000256|RuleBase:RU000682};
KW Reference proteome {ECO:0000313|Proteomes:UP000008549}.
FT DOMAIN 182..242
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 184..243
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 236..291
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 378..438
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 378..394
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 395..420
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 421..438
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 438 AA; 49329 MW; D1A547DFA6EFE280 CRC64;
MFTPEQFSKV MSQLGNFSQL GQMFQPGNLA MLQALQANGS TATPSLFPTM PVIPSLAAPS
SPTTSNLTVD QIVKTCKKLE SEGDVDGLFR FMCTIPPQTV QEVSANETYL RARALVCFHA
GHFRELYSIL ENNKFSHEYH PKLQEMWHEA HYREQEKNRG KSLCAVDKYR VRKKFPMPRT
IWDGEQKTHC FKERTRSLLR EWYLKDPYPN PPKKKELASA TGLTQMQVGN WFKNRRQRDR
AAAAKNKMNT TGVELRKIAS DMSESDDDFD DSMTDSPSPI DEPKDLSKSN LSKLQPSLLP
KITTPFDMFA AASSNPLLMM NPAMFLQFHS FLNSMKNCQG EEDENLEASV KVEADDEEIK
KKRSKLSIDE ILNIKSEVSP SQCSPCSNES LSPKQTPKKE VKKEVDDEAA AEEDSGSVNS
ERSDPSEASP KSSTSQSE
//
