ID A8YX63_LACH4 Unreviewed; 454 AA.
AC A8YX63;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 15-JAN-2008, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=HD superfamily phosphohydrolase {ECO:0000313|EMBL:ABX26486.1};
GN OrderedLocusNames=lhv_0244 {ECO:0000313|EMBL:ABX26486.1};
OS Lactobacillus helveticus (strain DPC 4571).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactobacillus.
OX NCBI_TaxID=405566 {ECO:0000313|EMBL:ABX26486.1, ECO:0000313|Proteomes:UP000000790};
RN [1] {ECO:0000313|EMBL:ABX26486.1, ECO:0000313|Proteomes:UP000000790}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DPC 4571 {ECO:0000313|EMBL:ABX26486.1,
RC ECO:0000313|Proteomes:UP000000790};
RX PubMed=17993529; DOI=10.1128/JB.01295-07;
RA Callanan M., Kaleta P., O'Callaghan J., O'Sullivan O., Jordan K.,
RA McAuliffe O., Sangrador-Vegas A., Slattery L., Fitzgerald G.F.,
RA Beresford T., Ross R.P.;
RT "Genome sequence of Lactobacillus helveticus: an organism distinguished by
RT selective gene loss and IS element expansion.";
RL J. Bacteriol. 190:727-735(2008).
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DR EMBL; CP000517; ABX26486.1; -; Genomic_DNA.
DR RefSeq; WP_012211340.1; NC_010080.1.
DR AlphaFoldDB; A8YX63; -.
DR KEGG; lhe:lhv_0244; -.
DR eggNOG; COG1078; Bacteria.
DR HOGENOM; CLU_026821_0_0_9; -.
DR Proteomes; UP000000790; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd00077; HDc; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR045509; HD_assoc_2.
DR InterPro; IPR006674; HD_domain.
DR PANTHER; PTHR11373; DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE; 1.
DR PANTHER; PTHR11373:SF4; DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1; 1.
DR Pfam; PF01966; HD; 1.
DR Pfam; PF19276; HD_assoc_2; 1.
DR SMART; SM00471; HDc; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR PROSITE; PS51831; HD; 1.
PE 4: Predicted;
FT DOMAIN 62..187
FT /note="HD"
FT /evidence="ECO:0000259|PROSITE:PS51831"
SQ SEQUENCE 454 AA; 52725 MW; 93B6461B5F4F3E0C CRC64;
MARFQSKKLK QEVVLRDPVH GYIHIEDKVI LDVFKSKEFQ RMRRIKQLGP VSYVFPGATH
TRFEHNLGVY ELTRRICDIF AKKYPSITPG DGLWNDDNRL LVECAGLLHD IGHGPYSHTF
EHLFNTNHEK IGQKIITDPN TEISKALKQV APNFPELVAS VIAKTYPNPQ VVKMISSQAD
ADRMDYLQRD AYFTGVNYGR FDLSRILRVI RPYQNGICFT NNGMHAVEDY IVSRYQMYQQ
VYFHRVGRSM EVILQHLLER AKDIYKKGNL KVTSSLASFL EGNWTLDDYL NLDDGVMETN
FLIWTEAQDP ILSDLAKRYL YRKPFASVRI DEETKNLLPK LRNIIKQTGF NPDYYTATNS
AFDEPYDAYK PSGKNANSQI EIMQDDGSLI ELSQLSPLVR ALNGTFQGDE RFFFPKTMLS
HDEDQPQIFD PLYEQFQKYV KNGALRYLRK PRKK
//
