ID A8YXH7_LACH4 Unreviewed; 407 AA.
AC A8YXH7;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 15-JAN-2008, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Transposase {ECO:0000313|EMBL:ABX26508.1};
GN OrderedLocusNames=lhv_0278 {ECO:0000313|EMBL:ABX26508.1};
OS Lactobacillus helveticus (strain DPC 4571).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactobacillus.
OX NCBI_TaxID=405566 {ECO:0000313|EMBL:ABX26508.1, ECO:0000313|Proteomes:UP000000790};
RN [1] {ECO:0000313|EMBL:ABX26508.1, ECO:0000313|Proteomes:UP000000790}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DPC 4571 {ECO:0000313|EMBL:ABX26508.1,
RC ECO:0000313|Proteomes:UP000000790};
RX PubMed=17993529; DOI=10.1128/JB.01295-07;
RA Callanan M., Kaleta P., O'Callaghan J., O'Sullivan O., Jordan K.,
RA McAuliffe O., Sangrador-Vegas A., Slattery L., Fitzgerald G.F.,
RA Beresford T., Ross R.P.;
RT "Genome sequence of Lactobacillus helveticus: an organism distinguished by
RT selective gene loss and IS element expansion.";
RL J. Bacteriol. 190:727-735(2008).
CC -!- SIMILARITY: In the C-terminal section; belongs to the transposase 35
CC family. {ECO:0000256|ARBA:ARBA00008761}.
CC -!- SIMILARITY: In the N-terminal section; belongs to the transposase 2
CC family. {ECO:0000256|ARBA:ARBA00011044}.
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DR EMBL; CP000517; ABX26508.1; -; Genomic_DNA.
DR AlphaFoldDB; A8YXH7; -.
DR KEGG; lhe:lhv_0278; -.
DR eggNOG; COG0675; Bacteria.
DR HOGENOM; CLU_032903_0_0_9; -.
DR Proteomes; UP000000790; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0032196; P:transposition; IEA:UniProtKB-KW.
DR InterPro; IPR010095; Cas12f1-like_TNB.
DR InterPro; IPR001959; Transposase.
DR InterPro; IPR021027; Transposase_put_HTH.
DR NCBIfam; NF040570; guided_TnpB; 1.
DR NCBIfam; TIGR01766; IS200/IS605 family accessory protein TnpB-like domain; 1.
DR PANTHER; PTHR30405:SF20; RNA-GUIDED DNA ENDONUCLEASE INSQ-RELATED; 1.
DR PANTHER; PTHR30405; TRANSPOSASE; 1.
DR Pfam; PF12323; HTH_OrfB_IS605; 1.
DR Pfam; PF01385; OrfB_IS605; 1.
DR Pfam; PF07282; OrfB_Zn_ribbon; 1.
PE 3: Inferred from homology;
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Transposition {ECO:0000256|ARBA:ARBA00022578};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 14..58
FT /note="Transposase putative helix-turn-helix"
FT /evidence="ECO:0000259|Pfam:PF12323"
FT DOMAIN 179..313
FT /note="Probable transposase IS891/IS1136/IS1341"
FT /evidence="ECO:0000259|Pfam:PF01385"
FT DOMAIN 325..394
FT /note="Cas12f1-like TNB"
FT /evidence="ECO:0000259|Pfam:PF07282"
SQ SEQUENCE 407 AA; 47519 MW; 263A81817948F3A6 CRC64;
MFDIISKRKE GTNVLKGIKL RLYPNRTQQN QLEQMFGNDR FVWNQMLAMM NERYQNNKAL
PFLGKFKLNY LLKPLKKEYP FLKTSDSSSL QVVNEFLTQS WKNFFQDKTG QIGKPRFHSR
KYLKKSYTGK SIIKTAGKRY LKIPKLGYVK TSKTGVLQNT KIKRYTVLLE PTRKYYLSLQ
VEISEPEKYS LTGKRVGIDV GVADLAILSN GLKYPSFNSS YFEKKAKIWQ RKYARRRHLA
KLLVLQDRNK KVLCPRSLES FTNWQKAQKS KAKYQAKAAN QRRDYLHKLT THLVKQYDVI
AIEDLKTKNL QKNHHLAKSI ANASWRMFRQ MLEYKCEWYG KKLIAVDPKN TSRICSKCVY
NSGAKPLEIR EWTCSKCQTK HDRDINAAVN ILHKATPTGQ GLTMVTS
//
