ID A9AV11_HERA2 Unreviewed; 3093 AA.
AC A9AV11;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 15-JAN-2008, sequence version 1.
DT 27-MAR-2024, entry version 95.
DE SubName: Full=Beta-ketoacyl synthase {ECO:0000313|EMBL:ABX06599.1};
GN OrderedLocusNames=Haur_3967 {ECO:0000313|EMBL:ABX06599.1};
OS Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95).
OC Bacteria; Chloroflexota; Chloroflexia; Herpetosiphonales;
OC Herpetosiphonaceae; Herpetosiphon.
OX NCBI_TaxID=316274 {ECO:0000313|EMBL:ABX06599.1, ECO:0000313|Proteomes:UP000000787};
RN [1] {ECO:0000313|Proteomes:UP000000787}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 23779 / DSM 785 / 114-95
RC {ECO:0000313|Proteomes:UP000000787};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Detter J.C., Han C.,
RA Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E.,
RA Bryant D.A., Richardson P.;
RT "Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.";
RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ABX06599.1, ECO:0000313|Proteomes:UP000000787}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 23779 / DSM 785 / 114-95
RC {ECO:0000313|Proteomes:UP000000787};
RX PubMed=22675585; DOI=10.4056/sigs.2194987;
RA Kiss H., Nett M., Domin N., Martin K., Maresca J.A., Copeland A.,
RA Lapidus A., Lucas S., Berry K.W., Glavina Del Rio T., Dalin E., Tice H.,
RA Pitluck S., Richardson P., Bruce D., Goodwin L., Han C., Detter J.C.,
RA Schmutz J., Brettin T., Land M., Hauser L., Kyrpides N.C., Ivanova N.,
RA Goker M., Woyke T., Klenk H.P., Bryant D.A.;
RT "Complete genome sequence of the filamentous gliding predatory bacterium
RT Herpetosiphon aurantiacus type strain (114-95(T)).";
RL Stand. Genomic Sci. 5:356-370(2011).
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DR EMBL; CP000875; ABX06599.1; -; Genomic_DNA.
DR STRING; 316274.Haur_3967; -.
DR KEGG; hau:Haur_3967; -.
DR eggNOG; COG1028; Bacteria.
DR eggNOG; COG3321; Bacteria.
DR eggNOG; COG4221; Bacteria.
DR HOGENOM; CLU_000022_29_0_0; -.
DR InParanoid; A9AV11; -.
DR BioCyc; HAUR316274:GHYA-4009-MONOMER; -.
DR Proteomes; UP000000787; Chromosome.
DR GO; GO:0016746; F:acyltransferase activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR CDD; cd08953; KR_2_SDR_x; 2.
DR CDD; cd00833; PKS; 2.
DR Gene3D; 3.30.70.3290; -; 2.
DR Gene3D; 3.40.47.10; -; 2.
DR Gene3D; 1.10.1200.10; ACP-like; 2.
DR Gene3D; 3.30.70.250; Malonyl-CoA ACP transacylase, ACP-binding; 2.
DR Gene3D; 3.40.366.10; Malonyl-Coenzyme A Acyl Carrier Protein, domain 2; 2.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR001227; Ac_transferase_dom_sf.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR014043; Acyl_transferase.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR049490; C883_1060-like_KR_N.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR016036; Malonyl_transacylase_ACP-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR032821; PKS_assoc.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR013968; PKS_KR.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR43775:SF37; FATTY ACID SYNTHASE; 1.
DR Pfam; PF00698; Acyl_transf_1; 2.
DR Pfam; PF21394; Beta-ketacyl_N; 2.
DR Pfam; PF16197; KAsynt_C_assoc; 2.
DR Pfam; PF00109; ketoacyl-synt; 2.
DR Pfam; PF02801; Ketoacyl-synt_C; 2.
DR Pfam; PF08659; KR; 2.
DR Pfam; PF00550; PP-binding; 2.
DR SMART; SM00827; PKS_AT; 2.
DR SMART; SM00822; PKS_KR; 2.
DR SMART; SM00825; PKS_KS; 2.
DR SMART; SM00823; PKS_PP; 2.
DR SUPFAM; SSF47336; ACP-like; 2.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 2.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 4.
DR SUPFAM; SSF55048; Probable ACP-binding domain of malonyl-CoA ACP transacylase; 2.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS50075; CARRIER; 2.
DR PROSITE; PS52004; KS3_2; 2.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 2.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 10..438
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT DOMAIN 1449..1524
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 1550..1976
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT DOMAIN 3000..3075
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 3093 AA; 330089 MW; 1EA71C0E5B3775E4 CRC64;
MTGSTATNYN GAVAIIGITG RFPDARDVAA FWQNLVAGVR SIRSFTDAEL LAAGVDPEVL
NDPNFVKHGT RLDDIELFDA AFFGYTPREA EVMDPQHRLF LECAWQALEQ AGYDPEGFRG
AIGVFAGSAT STYRGNNLHT NREIAEAAGG LQLAVGNDVD SLASTVSYKL NLRGPSVAVQ
TFCSTSLVAV HMACQSLLTY ECGLALAGGA VIAVPQGEGY MYQEGGILSP DGHCRTFDAK
AQGSVMSNGV GVVLLKRMTD ALKDGDTIYA VIRGSAVNND GIRKVGYTAP GLNGQSSVIT
IAQSRAKVAP ETVSYIEAHG TATPLGDSIE LAALIKAFER GAPRKQSCAL GSVKPNMGHL
DRASGVTGLI KTTMALHHRQ LPPNLDFEAP SPDIDLANSP FYVNTQLREW PANGAAPRRA
GVNSFGLGGT NVHVVLEEAP APAPVAPARP AQLLVLSAKT ATALEAMTDN LAAYLAGAPV
DLADVAFTLQ VGRAGFNHRR ILVGDSVADV RAALVAKDSR RVLSATQTGR NRPVAFVFPG
VGDHYAGMAG TLYATEAVFR EAVDQCAELL APRLGQDLRA ALYPADQPAA TAAHTLFAAT
AASSRVAGAL HQTALAQPAV FVVEYALVQL LASWGIRPQA LLGYSLGEYV AATVAGVLSL
EDALTLVAKR AQWIQAQPHG AMLAVSLGVE AIQPYLNTEV ALAVVNSPMT CVLAGSQPAL
AALAERFAAA DVASRWLETS HAFHSPMLAP VAAELTALVR TLRLQTPKIP YISNVTGTWI
TDAEATDPGY WARHMVETVQ FADGVGTLLA DAQLALLEVG PGQALGSFIR QHPTCGRTRF
GQIVATLPGA TEPQRDLIAL LEGLGRLWLA GVPVDWAGFH GGAARRRVPL PTYPFERKRF
WIDAPKREWA AANQPATVGK RADIADWFYR PEWAPAALNA PTNDSKQRWL IFVDAMGIGA
GVRQRLAEHG HEAVTVTIGE GFKRLDTHHY ELAPTRLADY LDLIAAIQGQ DPLPTHVLHL
WSLTPLAGIK SGAARFAAAQ DYCFTSLLNL ARAFEAQVIT DSIHMLVVSK GMQAVDPSDI
PDADNATLLG ACTVIGQENT SIIVRSVDLD VDLDARHLDG YAAGLIAEGQ SGSHDLHVAY
RDGQRFAERY VPLRLEALSQ PILRPGGVYL MTGGLGGVGL ILAEHLARTA QAKLVLVGRQ
GLPERAAWDA WLREHGADDA TSQRIQRVRT IESAGGVVEV VAADVADPEQ MRRAVAIAEA
RFGPINGVLH AAGISDDTAF RLIQTLEQAT YAAHFQPKVY GLYALEAALG DRPLDFCVLC
SSVSSVLGGL GFAGYAAANC FIDAFTQRHN RTHAVPWVSV NWDTWHLRAG QHDVTGLTVA
QYEMSPAEGA AAFERVAAAR GHSQIINSTG DLDARIRQWV RLESIRNDAA VAPAPASNGR
PELSTTYVAP IGEYEQRVSA IWQHVLGIDE IGLHDNFFDL GGNSLIALQL IARLKKEFKT
HISAVALFEA PTVSTMAQYL RPEVAPEEHV DQERLLIEHR REQTRQTVQA DGIAIIGMVG
RFPGASSVEE LWQNLHNGVE STTHFTDAEL LAAGVDPMQV YHPDYVKSRP ILQEDITLFD
AAFFGYTPRE AEFLDPQQRL FHECAWEALE QAGYDTQRYP GLVGVFGGTN TNAYLNRIAR
DPRSDGHITE IITLENDKDA LATNVAYKLN LRGPSFAVQT FCSTSLVATH LACRSLRHGE
CDIALAGGVS VRVPVNTGYL YEEGDQVSPD GHCRTFDANA GGATFGDGVA IVVLKRLADA
LADGDTIHAV IRGSAINNDG GLKVGYTAPS VVGQAAVVQA ALADANLAAD AISYVEAHGT
ATKLGDPIEV ASLTKAYRTT TDKVGFCAIS SVKPNVGHLD RASGATGLIK TVMALKHNVI
PATLHFQTPN PEIDFASSPF FVPTALTPWT RNGTPRRAGV NSLGVGGTNA HVIVEEAPQV
GPSGPGRAVE LLVLSAKTAT ALEAATTNLA AYLEEQPMVN LADVAHTLQV GRRVFEHRRV
VVARDVADAV GLLRSGDARR VLTLAQKPTS RGVAFVFPGV GDHYIGMAEG LYATEGVFRA
TVDRCCALLT PLLGSPIRKE IYPDGGVPAQ TGVDLRAMLR QDATPRSAGR LHQTAWAQPA
VFVVEYALVQ LLASWGIRPQ ALLGYSVGEY VAAAVAGVLS LEDALTLVAK RAQWIQAQPA
GSMLAVSLSA EAIGAYVGGA VALAVVNSPM TCVLAGPQAA LEAVKTRLDG DEVASRWLET
SHAFHSPMLA PVQAELTALV RTLRLQAPRI PYISNITGTW ITDAEATDPG YWARHMVETV
QFADGVGTLL ADAQLVVLEV GPGQALGSFI RQHPACGRDR FGQIVATVCG MTDTSDDLEV
LLSALGRLWL HDVVVDWASF RGSEVRQRIP LPTYPFERQR FWIELPPNPR GDSGRKVRRF
DAGDWYAVPS WKRAVAHDEL IDGAAGLGDQ GSWLVLADGE GLAAGLTAWL EERGQTVITV
TPGAAFAQHS ATAYTVRAGS REDFTALLQT LERHGQMPSR IVHAWLATPK VGAAQLDDVG
LAESLDLGFY SLLALAQALG EQDIEWCEIN VLTSEMHDIN GREELNVAAA AVIGPCKIIP
VEYPNLTARS IDILLPASPA ERATLVAQIG AELATPPTGD LVAFRGAHRW VQMMEPVALP
TAPASHPRLR TGGVYLLTGG LGGIALGLAR DLAATLQAKL VLVNRSSLPD RATWPALLER
DGAEQGVGRR IQQVLDLEAL GAEVLVIQAD VTDAVAMARA VAEAQARFGT IHGVLHTAGV
PGVGLMQLKD AATAAAELAP KVQGTLALTR ALAGVPLDFL VLFSSVTSAT GGGPGQVAYC
AANAFLDAYA RKHATDHGRT VAVSWGEWLW DAWSDGLQGF SAEDQLRFRA YRRTFGITFD
EGAEALRRIL ACRISHLFVT TEDVVAMFED SKGSALQRAA RQEDAAQRYP RPEVSTSFVE
PQSELEQQVS AIWSEVLGIA PIGVNDNFFD LGGNSLIGIQ IVTRLRRTFQ VALPLTILFD
APTVEEMSIA IEMMLIDAIE HSSESAAESV SRV
//
