ID   A9B7I0_HERA2            Unreviewed;       774 AA.
AC   A9B7I0;
DT   15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT   15-JAN-2008, sequence version 1.
DT   27-MAR-2024, entry version 79.
DE   RecName: Full=Glucosylceramidase {ECO:0008006|Google:ProtNLM};
GN   OrderedLocusNames=Haur_0301 {ECO:0000313|EMBL:ABX02953.1};
OS   Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95).
OC   Bacteria; Chloroflexota; Chloroflexia; Herpetosiphonales;
OC   Herpetosiphonaceae; Herpetosiphon.
OX   NCBI_TaxID=316274 {ECO:0000313|EMBL:ABX02953.1, ECO:0000313|Proteomes:UP000000787};
RN   [1] {ECO:0000313|Proteomes:UP000000787}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 23779 / DSM 785 / 114-95
RC   {ECO:0000313|Proteomes:UP000000787};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA   Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Detter J.C., Han C.,
RA   Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E.,
RA   Bryant D.A., Richardson P.;
RT   "Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.";
RL   Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ABX02953.1, ECO:0000313|Proteomes:UP000000787}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 23779 / DSM 785 / 114-95
RC   {ECO:0000313|Proteomes:UP000000787};
RX   PubMed=22675585; DOI=10.4056/sigs.2194987;
RA   Kiss H., Nett M., Domin N., Martin K., Maresca J.A., Copeland A.,
RA   Lapidus A., Lucas S., Berry K.W., Glavina Del Rio T., Dalin E., Tice H.,
RA   Pitluck S., Richardson P., Bruce D., Goodwin L., Han C., Detter J.C.,
RA   Schmutz J., Brettin T., Land M., Hauser L., Kyrpides N.C., Ivanova N.,
RA   Goker M., Woyke T., Klenk H.P., Bryant D.A.;
RT   "Complete genome sequence of the filamentous gliding predatory bacterium
RT   Herpetosiphon aurantiacus type strain (114-95(T)).";
RL   Stand. Genomic Sci. 5:356-370(2011).
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DR   EMBL; CP000875; ABX02953.1; -; Genomic_DNA.
DR   AlphaFoldDB; A9B7I0; -.
DR   STRING; 316274.Haur_0301; -.
DR   CAZy; GH116; Glycoside Hydrolase Family 116.
DR   KEGG; hau:Haur_0301; -.
DR   eggNOG; COG4354; Bacteria.
DR   HOGENOM; CLU_006322_1_0_0; -.
DR   InParanoid; A9B7I0; -.
DR   BioCyc; HAUR316274:GHYA-304-MONOMER; -.
DR   Proteomes; UP000000787; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0004348; F:glucosylceramidase activity; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0006680; P:glucosylceramide catabolic process; IEA:InterPro.
DR   Gene3D; 1.50.10.10; -; 1.
DR   InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR   InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR   InterPro; IPR014551; B_Glucosidase_GBA2-typ.
DR   InterPro; IPR006775; GH116_catalytic.
DR   InterPro; IPR024462; GH116_N.
DR   PANTHER; PTHR12654; BILE ACID BETA-GLUCOSIDASE-RELATED; 1.
DR   PANTHER; PTHR12654:SF0; NON-LYSOSOMAL GLUCOSYLCERAMIDASE; 1.
DR   Pfam; PF04685; DUF608; 1.
DR   Pfam; PF12215; Glyco_hydr_116N; 1.
DR   PIRSF; PIRSF028944; Beta_gluc_GBA2; 1.
DR   SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
PE   4: Predicted;
FT   DOMAIN          44..348
FT                   /note="Glycosyl-hydrolase family 116 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12215"
FT   DOMAIN          403..763
FT                   /note="Glycosyl-hydrolase family 116 catalytic region"
FT                   /evidence="ECO:0000259|Pfam:PF04685"
SQ   SEQUENCE   774 AA;  86230 MW;  F6D2165F84264861 CRC64;
     MTEQRHHSSI PLAAWQRPLG LDYPNAAIAA HDHGPIIDDG VFHGLPIGGM GSGAIGRNFR
     GDWSRWHLEV GKHVHRSVWP NQWSVFWQTA SQQAAQVLCT TQPDTDELSS WNWNYPVGAG
     NYHALFPRAW FDYQHPDWPL ELVQEQFSPV LAGNLKESSF PVGVFTWRVT NRGSETVRLG
     LMLTWEHTRA VEAAGLSLQR QHSAWNDGNT SGVTLTQTSD QALSSHNGTW ALAVQAPESA
     SVSQWTCWDV AQDAAALWQD FASDGQLADY PTSQKVAADQ RSATAIAVTL ELAPGASAVI
     PFSLAWDFPI VEFADQSRWY KRYTRFWGTN GDQAQALAVA SLTNADAWRT AIEAWQNPIL
     ADDQRPFWYK SALFNELYYL VDGGTLWVDR AVGGPEPAAD DVGLFSYLEC YDYPFYGTLD
     VSFYSSWSIL ALWPELERGE ILAFSKTVND ADDTVVTIVA TQVPAIRKAA GALPHDLGAP
     KEQPLIKTNA YDFQDINNWK DLNLKYILRI YRDVSLWNDQ AMLEATWDTI PTALEYVHQF
     DSDGDGLLDH SGADQTYDTW AMSGAASYSA SLLICALEAA IRLAQRMGDH AQADAWSEWL
     AAARQSFETK LWNGTYFRYH TADTDLREVI MADQLVGQWY AGAIGLPAVA PREMIRSALQ
     TVYRFNVMQY ANGALGAVNG MHPDGTVDTS SNQASEVWSG TTYAIAAMML QEGLDLEGWQ
     TAWGAYNATY NELGLWFRTP EAWGIERTFR ASMYMRPQSI WAIEHALAVR AKNA
//