ID A9BB38_PROM4 Unreviewed; 300 AA.
AC A9BB38;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 15-JAN-2008, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=Polyprenyl synthetase {ECO:0000313|EMBL:ABX09050.1};
DE EC=2.5.1.1 {ECO:0000313|EMBL:ABX09050.1};
DE EC=2.5.1.10 {ECO:0000313|EMBL:ABX09050.1};
DE EC=2.5.1.29 {ECO:0000313|EMBL:ABX09050.1};
GN Name=ispA {ECO:0000313|EMBL:ABX09050.1};
GN OrderedLocusNames=P9211_11191 {ECO:0000313|EMBL:ABX09050.1};
OS Prochlorococcus marinus (strain MIT 9211).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Synechococcales;
OC Prochlorococcaceae; Prochlorococcus.
OX NCBI_TaxID=93059 {ECO:0000313|EMBL:ABX09050.1, ECO:0000313|Proteomes:UP000000788};
RN [1] {ECO:0000313|EMBL:ABX09050.1, ECO:0000313|Proteomes:UP000000788}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MIT 9211 {ECO:0000313|Proteomes:UP000000788};
RX PubMed=18159947; DOI=10.1371/journal.pgen.0030231;
RA Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S.,
RA Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M.,
RA Richardson P., Chisholm S.W.;
RT "Patterns and implications of gene gain and loss in the evolution of
RT Prochlorococcus.";
RL PLoS Genet. 3:2515-2528(2007).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|RuleBase:RU004466}.
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DR EMBL; CP000878; ABX09050.1; -; Genomic_DNA.
DR RefSeq; WP_012195671.1; NC_009976.1.
DR AlphaFoldDB; A9BB38; -.
DR STRING; 93059.P9211_11191; -.
DR KEGG; pmj:P9211_11191; -.
DR eggNOG; COG0142; Bacteria.
DR HOGENOM; CLU_014015_0_0_3; -.
DR OrthoDB; 9805316at2; -.
DR Proteomes; UP000000788; Chromosome.
DR GO; GO:0004161; F:dimethylallyltranstransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0004311; F:farnesyltranstransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0004337; F:geranyltranstransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR CDD; cd00685; Trans_IPPS_HT; 1.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR PANTHER; PTHR43281; FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR43281:SF1; FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SFLD; SFLDG01017; Polyprenyl_Transferase_Like; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
DR PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
DR PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
PE 3: Inferred from homology;
KW Isoprene biosynthesis {ECO:0000256|ARBA:ARBA00023229};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Reference proteome {ECO:0000313|Proteomes:UP000000788};
KW Transferase {ECO:0000256|RuleBase:RU004466, ECO:0000313|EMBL:ABX09050.1}.
SQ SEQUENCE 300 AA; 32190 MW; FBF9876485F49559 CRC64;
MSEAVISSFD FAAYLAKEKI RVEAALDASL GPERPKQLRE AMRYSLLAGG KRLRPILCLA
ACELIAGESE TALPTAVAIE MIHTMSLIHD DLPSMDNDDL RRGRPTNHKV YGDALAILAG
DALLTRAFEM VSLRSPGISA ERLIKVVGEL SLVAGAPGLV GGQVADLECE GKDVDIDTLE
YIHIHKTGAL LKASVVCGAL IGGAKDDLLD ALRTYAEAIG LAFQIIDDIL DVTSSSEVLG
KTAGKDLIAD KTTYPKLLGV DESRQRAKVL IEKAKSVLEP WEDDATPLLA LADYIISRDR
//
