ID A9BBQ5_PROM4 Unreviewed; 313 AA.
AC A9BBQ5;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 15-JAN-2008, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE RecName: Full=RNA polymerase sigma factor {ECO:0000256|RuleBase:RU362124};
GN OrderedLocusNames=P9211_13361 {ECO:0000313|EMBL:ABX09267.1};
OS Prochlorococcus marinus (strain MIT 9211).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Synechococcales;
OC Prochlorococcaceae; Prochlorococcus.
OX NCBI_TaxID=93059 {ECO:0000313|EMBL:ABX09267.1, ECO:0000313|Proteomes:UP000000788};
RN [1] {ECO:0000313|EMBL:ABX09267.1, ECO:0000313|Proteomes:UP000000788}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MIT 9211 {ECO:0000313|Proteomes:UP000000788};
RX PubMed=18159947; DOI=10.1371/journal.pgen.0030231;
RA Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S.,
RA Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M.,
RA Richardson P., Chisholm S.W.;
RT "Patterns and implications of gene gain and loss in the evolution of
RT Prochlorococcus.";
RL PLoS Genet. 3:2515-2528(2007).
CC -!- FUNCTION: Sigma factors are initiation factors that promote the
CC attachment of RNA polymerase to specific initiation sites and are then
CC released. {ECO:0000256|RuleBase:RU362124}.
CC -!- SIMILARITY: Belongs to the sigma-70 factor family.
CC {ECO:0000256|ARBA:ARBA00007788, ECO:0000256|RuleBase:RU362124}.
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DR EMBL; CP000878; ABX09267.1; -; Genomic_DNA.
DR RefSeq; WP_012195888.1; NC_009976.1.
DR AlphaFoldDB; A9BBQ5; -.
DR STRING; 93059.P9211_13361; -.
DR KEGG; pmj:P9211_13361; -.
DR eggNOG; COG0568; Bacteria.
DR HOGENOM; CLU_014793_3_5_3; -.
DR OrthoDB; 537957at2; -.
DR Proteomes; UP000000788; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-KW.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR CDD; cd06171; Sigma70_r4; 1.
DR Gene3D; 1.10.601.10; RNA Polymerase Primary Sigma Factor; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR InterPro; IPR000943; RNA_pol_sigma70.
DR InterPro; IPR009042; RNA_pol_sigma70_r1_2.
DR InterPro; IPR007627; RNA_pol_sigma70_r2.
DR InterPro; IPR007624; RNA_pol_sigma70_r3.
DR InterPro; IPR007630; RNA_pol_sigma70_r4.
DR InterPro; IPR013325; RNA_pol_sigma_r2.
DR InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR InterPro; IPR017848; RNA_pol_sigma_RpoD/SigA_cyanob.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR02997; Sig70-cyanoRpoD; 1.
DR NCBIfam; TIGR02937; sigma70-ECF; 1.
DR PANTHER; PTHR30603; RNA POLYMERASE SIGMA FACTOR RPO; 1.
DR PANTHER; PTHR30603:SF47; RNA POLYMERASE SIGMA FACTOR SIGF, CHLOROPLASTIC; 1.
DR Pfam; PF00140; Sigma70_r1_2; 1.
DR Pfam; PF04542; Sigma70_r2; 1.
DR Pfam; PF04539; Sigma70_r3; 1.
DR Pfam; PF04545; Sigma70_r4; 1.
DR PRINTS; PR00046; SIGMA70FCT.
DR SUPFAM; SSF88946; Sigma2 domain of RNA polymerase sigma factors; 1.
DR SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 2.
DR PROSITE; PS00715; SIGMA70_1; 1.
DR PROSITE; PS00716; SIGMA70_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU362124};
KW Reference proteome {ECO:0000313|Proteomes:UP000000788};
KW Sigma factor {ECO:0000256|ARBA:ARBA00023082,
KW ECO:0000256|RuleBase:RU362124};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU362124};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU362124}.
FT DOMAIN 106..119
FT /note="RNA polymerase sigma-70"
FT /evidence="ECO:0000259|PROSITE:PS00715"
FT DOMAIN 276..302
FT /note="RNA polymerase sigma-70"
FT /evidence="ECO:0000259|PROSITE:PS00716"
SQ SEQUENCE 313 AA; 35543 MW; 12A992FE5FB7E140 CRC64;
MVSSAPKAAE SQKRRSSDPI SWYLSTIGRV PLLTPAEEIE LGNQVQVMMN LTEDGSIDVK
SEEFTSHQRR LIRIGRRAKE RMMKANLRLV VSVAKKYQGK GLELLDLVQE GSLGLERAVE
KFDPTRGYKF STYAFWWIRQ SMTRAIACQS RTIRLPVHLS ERLATIRKIS SDLAHKLGAM
PSRAELAEAM EIDAEELDSI LRQALTTSSL DAPVNGDDGR SFLGDLIADS SLEEPLDKVE
QRIHQEQLGR WLTHLSEQEQ HVLKLRFGLE GNERHTLAEI GRLLQVSRER VRQVELKSLR
KLRNLTRKLP SGI
//
