ID A9CGE0_AGRFC Unreviewed; 527 AA.
AC A9CGE0;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 15-JAN-2008, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Dehydrogenase {ECO:0000313|EMBL:AAK89143.1};
GN OrderedLocusNames=Atu4296 {ECO:0000313|EMBL:AAK89143.1};
OS Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens
OS (strain C58)).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Rhizobium/Agrobacterium group; Agrobacterium;
OC Agrobacterium tumefaciens complex.
OX NCBI_TaxID=176299 {ECO:0000313|EMBL:AAK89143.1, ECO:0000313|Proteomes:UP000000813};
RN [1] {ECO:0000313|EMBL:AAK89143.1, ECO:0000313|Proteomes:UP000000813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C58 / ATCC 33970 {ECO:0000313|Proteomes:UP000000813};
RX PubMed=11743193; DOI=10.1126/science.1066804;
RA Wood D.W., Setubal J.C., Kaul R., Monks D.E., Kitajima J.P., Okura V.K.,
RA Zhou Y., Chen L., Wood G.E., Almeida N.F.Jr., Woo L., Chen Y.,
RA Paulsen I.T., Eisen J.A., Karp P.D., Bovee D.Sr., Chapman P.,
RA Clendenning J., Deatherage G., Gillet W., Grant C., Kutyavin T., Levy R.,
RA Li M.J., McClelland E., Palmieri A., Raymond C., Rouse G.,
RA Saenphimmachak C., Wu Z., Romero P., Gordon D., Zhang S., Yoo H., Tao Y.,
RA Biddle P., Jung M., Krespan W., Perry M., Gordon-Kamm B., Liao L., Kim S.,
RA Hendrick C., Zhao Z.Y., Dolan M., Chumley F., Tingey S.V., Tomb J.F.,
RA Gordon M.P., Olson M.V., Nester E.W.;
RT "The genome of the natural genetic engineer Agrobacterium tumefaciens
RT C58.";
RL Science 294:2317-2323(2001).
RN [2] {ECO:0000313|EMBL:AAK89143.1, ECO:0000313|Proteomes:UP000000813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C58 / ATCC 33970 {ECO:0000313|Proteomes:UP000000813};
RX PubMed=11743194; DOI=10.1126/science.1066803;
RA Goodner B., Hinkle G., Gattung S., Miller N., Blanchard M., Qurollo B.,
RA Goldman B.S., Cao Y., Askenazi M., Halling C., Mullin L., Houmiel K.,
RA Gordon J., Vaudin M., Iartchouk O., Epp A., Liu F., Wollam C., Allinger M.,
RA Doughty D., Scott C., Lappas C., Markelz B., Flanagan C., Crowell C.,
RA Gurson J., Lomo C., Sear C., Strub G., Cielo C., Slater S.;
RT "Genome sequence of the plant pathogen and biotechnology agent
RT Agrobacterium tumefaciens C58.";
RL Science 294:2323-2328(2001).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00010790}.
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DR EMBL; AE007870; AAK89143.1; -; Genomic_DNA.
DR PIR; AD3084; AD3084.
DR PIR; E98202; E98202.
DR RefSeq; NP_356358.1; NC_003063.2.
DR RefSeq; WP_010973724.1; NC_003063.2.
DR AlphaFoldDB; A9CGE0; -.
DR SMR; A9CGE0; -.
DR STRING; 176299.Atu4296; -.
DR DNASU; 1136170; -.
DR EnsemblBacteria; AAK89143; AAK89143; Atu4296.
DR KEGG; atu:Atu4296; -.
DR PATRIC; fig|176299.10.peg.4105; -.
DR eggNOG; COG2303; Bacteria.
DR HOGENOM; CLU_008878_4_2_5; -.
DR OrthoDB; 9798604at2; -.
DR PhylomeDB; A9CGE0; -.
DR BioCyc; AGRO:ATU4296-MONOMER; -.
DR Proteomes; UP000000813; Chromosome linear.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR InterPro; IPR022357; MIP_CS.
DR PANTHER; PTHR42784; PYRANOSE 2-OXIDASE; 1.
DR PANTHER; PTHR42784:SF1; PYRANOSE 2-OXIDASE; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR Pfam; PF00732; GMC_oxred_N; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR PROSITE; PS00221; MIP; 1.
PE 3: Inferred from homology;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000000813}.
FT DOMAIN 14..46
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
FT DOMAIN 86..307
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00732"
FT DOMAIN 409..500
FT /note="Glucose-methanol-choline oxidoreductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05199"
SQ SEQUENCE 527 AA; 57884 MW; 2DD0D361880C27AE CRC64;
MSFSSKGDPG SKPDIVIIGS GVGGSAVALK LAATGAKILI IERGEKLPNE PENADAEAVF
VQNRYRTTDL YRDETGRTYR PGQYYYVGGH TKFYGTAMFR FRDRDFREVE HEDGVSPAWP
VSYAELEPFY AEAERLFGVR GRAGDDPTEP PRSAPYMHAP IPHEPVIGRV AKGFERLGLR
PFHMPSAIDY GPGGLCRRCG TCDAFVCRFD AKGDAETRLL RPALRHPNVS LLTGARVRRL
IADGDGKHIV AVEIERAGEI TTIEAPLFVL SAGAINSALI LLRSADEKKP NGLANSSGVV
GRYLMNHHLS GLMGLLPFTI NDTRFPKTMS LNDFFDGTPG DEAARGNVQM LGNIQGPMIR
AAYPWMPRPL ANLLARHSVD FLVMSEDTPK YDSRVKPWGK NGAELIYRPG DREAHQRFVR
HMRSLLRKNG FPVVLGHSFG IEAPSHQCGT VRMGDDPKEA ALNALCQTYD HPNLYVVDAG
FFPSSAALNP ALTVAAQALR VGDHIRQSRF SSLRAHDILS SENNHAP
//
