ID A9CIA6_AGRFC Unreviewed; 580 AA.
AC A9CIA6;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 15-JAN-2008, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Penicillin binding protein 2 {ECO:0000313|EMBL:AAK87850.1};
GN Name=pbpB1 {ECO:0000313|EMBL:AAK87850.1};
GN OrderedLocusNames=Atu2100 {ECO:0000313|EMBL:AAK87850.1};
OS Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens
OS (strain C58)).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Rhizobium/Agrobacterium group; Agrobacterium;
OC Agrobacterium tumefaciens complex.
OX NCBI_TaxID=176299 {ECO:0000313|EMBL:AAK87850.1, ECO:0000313|Proteomes:UP000000813};
RN [1] {ECO:0000313|EMBL:AAK87850.1, ECO:0000313|Proteomes:UP000000813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C58 / ATCC 33970 {ECO:0000313|Proteomes:UP000000813};
RX PubMed=11743193; DOI=10.1126/science.1066804;
RA Wood D.W., Setubal J.C., Kaul R., Monks D.E., Kitajima J.P., Okura V.K.,
RA Zhou Y., Chen L., Wood G.E., Almeida N.F.Jr., Woo L., Chen Y.,
RA Paulsen I.T., Eisen J.A., Karp P.D., Bovee D.Sr., Chapman P.,
RA Clendenning J., Deatherage G., Gillet W., Grant C., Kutyavin T., Levy R.,
RA Li M.J., McClelland E., Palmieri A., Raymond C., Rouse G.,
RA Saenphimmachak C., Wu Z., Romero P., Gordon D., Zhang S., Yoo H., Tao Y.,
RA Biddle P., Jung M., Krespan W., Perry M., Gordon-Kamm B., Liao L., Kim S.,
RA Hendrick C., Zhao Z.Y., Dolan M., Chumley F., Tingey S.V., Tomb J.F.,
RA Gordon M.P., Olson M.V., Nester E.W.;
RT "The genome of the natural genetic engineer Agrobacterium tumefaciens
RT C58.";
RL Science 294:2317-2323(2001).
RN [2] {ECO:0000313|EMBL:AAK87850.1, ECO:0000313|Proteomes:UP000000813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C58 / ATCC 33970 {ECO:0000313|Proteomes:UP000000813};
RX PubMed=11743194; DOI=10.1126/science.1066803;
RA Goodner B., Hinkle G., Gattung S., Miller N., Blanchard M., Qurollo B.,
RA Goldman B.S., Cao Y., Askenazi M., Halling C., Mullin L., Houmiel K.,
RA Gordon J., Vaudin M., Iartchouk O., Epp A., Liu F., Wollam C., Allinger M.,
RA Doughty D., Scott C., Lappas C., Markelz B., Flanagan C., Crowell C.,
RA Gurson J., Lomo C., Sear C., Strub G., Cielo C., Slater S.;
RT "Genome sequence of the plant pathogen and biotechnology agent
RT Agrobacterium tumefaciens C58.";
RL Science 294:2323-2328(2001).
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DR EMBL; AE007869; AAK87850.1; -; Genomic_DNA.
DR PIR; A97612; A97612.
DR PIR; AE2834; AE2834.
DR RefSeq; NP_355065.1; NC_003062.2.
DR RefSeq; WP_006310452.1; NC_003062.2.
DR AlphaFoldDB; A9CIA6; -.
DR STRING; 176299.Atu2100; -.
DR EnsemblBacteria; AAK87850; AAK87850; Atu2100.
DR GeneID; 66222307; -.
DR KEGG; atu:Atu2100; -.
DR PATRIC; fig|176299.10.peg.2114; -.
DR eggNOG; COG0768; Bacteria.
DR HOGENOM; CLU_009289_6_2_5; -.
DR OrthoDB; 9789078at2; -.
DR PhylomeDB; A9CIA6; -.
DR BioCyc; AGRO:ATU2100-MONOMER; -.
DR Proteomes; UP000000813; Chromosome circular.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000813};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 45..64
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 85..193
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 257..555
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 580 AA; 62858 MW; B6D4CB07CE9511DC CRC64;
MSFLSRVMVL KSKAHFSAST TGVYTDHAAF EGARKKRAAQ AKSRVGLLIF GFIAFYAVVG
GRLVQYGMAE QETVSSIAPA DRLMASRPDL LDRNGEVLAT DIRTVSLFAE PHRIVDIDEA
IEKLRTVLPD LDQRGTYQKL TSNSRFQWLR RQLTPKQQSQ ILALGIPGVG FRPEKRRFYP
GGPTAAHVVG HVNIDNRGVA GMERYVDSQG LADLTALGMT SDQPLEPVKL SIDLRVQSIV
REVVTAAIAK FQAIGAGAVV LDVHTGEVLA MASVPDYDPN NPAEGAKEGW LNRMSNGTFE
MGSTFKSFTI AMGLDSGRVR LGDMFDARYP IRIGGFTIKD FHGKGRMLSV PEIFQFSSNI
GTAKIADTVG TEGHKEFLTR LGLLTRMQTE LPEVALPSQP REWKKINSIT ISFGHGVSTT
PLQTAVAGAA LVNGGKLIEP TFLPRTREQA DQVAKQVLKP GASKDMRFLF EWNGVNGSGR
NARVDGFNVG GKTGTADKVV NGRYVHDKNF NAFLSAFPMD DPQYVVLSFI DEPKTDKGNG
AALAGTSAAP MVHDIITRTA AVLGVKPKFG KDGSALLVSY
//
