ID A9CKE1_AGRFC Unreviewed; 524 AA.
AC A9CKE1;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 15-JAN-2008, sequence version 1.
DT 27-MAR-2024, entry version 91.
DE SubName: Full=Ubiquinone biosynthesis protein {ECO:0000313|EMBL:AAK86135.1};
GN Name=aarF {ECO:0000313|EMBL:AAK86135.1};
GN OrderedLocusNames=Atu0319 {ECO:0000313|EMBL:AAK86135.1};
OS Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens
OS (strain C58)).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Rhizobium/Agrobacterium group; Agrobacterium;
OC Agrobacterium tumefaciens complex.
OX NCBI_TaxID=176299 {ECO:0000313|EMBL:AAK86135.1, ECO:0000313|Proteomes:UP000000813};
RN [1] {ECO:0000313|EMBL:AAK86135.1, ECO:0000313|Proteomes:UP000000813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C58 / ATCC 33970 {ECO:0000313|Proteomes:UP000000813};
RX PubMed=11743193; DOI=10.1126/science.1066804;
RA Wood D.W., Setubal J.C., Kaul R., Monks D.E., Kitajima J.P., Okura V.K.,
RA Zhou Y., Chen L., Wood G.E., Almeida N.F.Jr., Woo L., Chen Y.,
RA Paulsen I.T., Eisen J.A., Karp P.D., Bovee D.Sr., Chapman P.,
RA Clendenning J., Deatherage G., Gillet W., Grant C., Kutyavin T., Levy R.,
RA Li M.J., McClelland E., Palmieri A., Raymond C., Rouse G.,
RA Saenphimmachak C., Wu Z., Romero P., Gordon D., Zhang S., Yoo H., Tao Y.,
RA Biddle P., Jung M., Krespan W., Perry M., Gordon-Kamm B., Liao L., Kim S.,
RA Hendrick C., Zhao Z.Y., Dolan M., Chumley F., Tingey S.V., Tomb J.F.,
RA Gordon M.P., Olson M.V., Nester E.W.;
RT "The genome of the natural genetic engineer Agrobacterium tumefaciens
RT C58.";
RL Science 294:2317-2323(2001).
RN [2] {ECO:0000313|EMBL:AAK86135.1, ECO:0000313|Proteomes:UP000000813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C58 / ATCC 33970 {ECO:0000313|Proteomes:UP000000813};
RX PubMed=11743194; DOI=10.1126/science.1066803;
RA Goodner B., Hinkle G., Gattung S., Miller N., Blanchard M., Qurollo B.,
RA Goldman B.S., Cao Y., Askenazi M., Halling C., Mullin L., Houmiel K.,
RA Gordon J., Vaudin M., Iartchouk O., Epp A., Liu F., Wollam C., Allinger M.,
RA Doughty D., Scott C., Lappas C., Markelz B., Flanagan C., Crowell C.,
RA Gurson J., Lomo C., Sear C., Strub G., Cielo C., Slater S.;
RT "Genome sequence of the plant pathogen and biotechnology agent
RT Agrobacterium tumefaciens C58.";
RL Science 294:2323-2328(2001).
CC -!- PATHWAY: Cofactor biosynthesis; ubiquinone biosynthesis [regulation].
CC {ECO:0000256|ARBA:ARBA00005020}.
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. ADCK protein
CC kinase family. {ECO:0000256|ARBA:ARBA00009670}.
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DR EMBL; AE007869; AAK86135.1; -; Genomic_DNA.
DR PIR; AG2615; AG2615.
DR PIR; F97397; F97397.
DR RefSeq; NP_353350.1; NC_003062.2.
DR RefSeq; WP_010970817.1; NC_003062.2.
DR AlphaFoldDB; A9CKE1; -.
DR STRING; 176299.Atu0319; -.
DR EnsemblBacteria; AAK86135; AAK86135; Atu0319.
DR KEGG; atu:Atu0319; -.
DR PATRIC; fig|176299.10.peg.311; -.
DR eggNOG; COG0661; Bacteria.
DR HOGENOM; CLU_006533_0_0_5; -.
DR OrthoDB; 9795390at2; -.
DR PhylomeDB; A9CKE1; -.
DR BioCyc; AGRO:ATU0319-MONOMER; -.
DR UniPathway; UPA00232; -.
DR Proteomes; UP000000813; Chromosome circular.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0006744; P:ubiquinone biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd13972; UbiB; 1.
DR InterPro; IPR004147; ABC1_dom.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR010232; UbiB.
DR InterPro; IPR045308; UbiB_bact.
DR NCBIfam; TIGR01982; UbiB; 1.
DR PANTHER; PTHR10566; CHAPERONE-ACTIVITY OF BC1 COMPLEX CABC1 -RELATED; 1.
DR PANTHER; PTHR10566:SF129; PROTEIN KINASE UBIB-RELATED; 1.
DR Pfam; PF03109; ABC1; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000000813};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Ubiquinone {ECO:0000313|EMBL:AAK86135.1};
KW Ubiquinone biosynthesis {ECO:0000256|ARBA:ARBA00022688}.
FT TRANSMEM 504..521
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 124..476
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
SQ SEQUENCE 524 AA; 58213 MW; 3265EB163003B420 CRC64;
MSTLGAYFRL ARVGWVLVRE GVVLALPSDD LPAPAQLLKA ALKPFARSKA KRAQRSDRLA
VAVERLGPSY VKMGQFLATR PDVVGADFAD DLASLQDRMA FFPAAAAKAN IEGSLGRSIS
ELYREFGDPI AAASIAQVHP AMVDTPKGPR KVAVKVIRPG VRQRFQNDLE AMYLIADLQQ
RFVRSARRLR PVEVTRTLEQ TTKIEMDLRL EAAALSELAE NTRQDPGFRV PEVDWERTGR
DVVTMEWIDG VKMSDIEGLK AAGHDLNKLA DTLIQSFLRH TLRDGFFHAD MHPGNLFVDA
KGEIVAVDMG IAGRLGKKER RFLAEILYGF ITRDYMRVAE VHFEAGYVPG HHDKASFAQA
IRAIGEPIHG QPAETISMGK LLTLLFEVTE LFDMETRPEL VMLQKTMVVV EGVSRMLNPR
FNMWKAADPV VGGWIRDNLG PKRIATDLKD GVKAALKLAE AVPEIAAKTE KLHSELMYMS
ENGLRFDAQT AEAIGKAEAR HTKWGRIALW VIALTLLYIA IRIS
//
