ID A9CS97_ENTBH Unreviewed; 388 AA.
AC A9CS97;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=19S-PA700 proteasome regulatory particle subunit Rpt4p-S10b {ECO:0000313|EMBL:EDQ31232.1};
DE EC=3.6.1.3 {ECO:0000313|EMBL:EDQ31232.1};
GN ORFNames=EBI_21983 {ECO:0000313|EMBL:EDQ31232.1};
OS Enterocytozoon bieneusi (strain H348) (Microsporidian parasite).
OC Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Enterocytozoonidae;
OC Enterocytozoon.
OX NCBI_TaxID=481877 {ECO:0000313|EMBL:EDQ31232.1, ECO:0000313|Proteomes:UP000001742};
RN [1] {ECO:0000313|EMBL:EDQ31232.1, ECO:0000313|Proteomes:UP000001742}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H348 {ECO:0000313|EMBL:EDQ31232.1,
RC ECO:0000313|Proteomes:UP000001742};
RX PubMed=18060071; DOI=10.1371/journal.pone.0001277;
RA Corradi N., Akiyoshi D.E., Morrison H.G., Feng X., Weiss L.M., Tzipori S.,
RA Keeling P.J.;
RT "Patterns of genome evolution among the microsporidian parasites
RT Encephalitozoon cuniculi, Antonospora locustae and Enterocytozoon
RT bieneusi.";
RL PLoS ONE 2:E1277-E1277(2007).
RN [2] {ECO:0000313|EMBL:EDQ31232.1, ECO:0000313|Proteomes:UP000001742}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H348 {ECO:0000313|EMBL:EDQ31232.1,
RC ECO:0000313|Proteomes:UP000001742};
RX PubMed=19132089; DOI=10.1371/journal.ppat.1000261;
RA Akiyoshi D.E., Morrison H.G., Lei S., Feng X., Zhang Q., Corradi N.,
RA Mayanja H., Tumwine J.K., Keeling P.J., Weiss L.M., Tzipori S.;
RT "Genomic survey of the non-cultivatable opportunistic human pathogen,
RT Enterocytozoon bieneusi.";
RL PLoS Pathog. 5:E1000261-E1000261(2009).
CC -!- SIMILARITY: Belongs to the AAA ATPase family.
CC {ECO:0000256|ARBA:ARBA00006914, ECO:0000256|RuleBase:RU003651}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDQ31232.1}.
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DR EMBL; ABGB01000002; EDQ31232.1; -; Genomic_DNA.
DR RefSeq; XP_001828080.1; XM_001828028.1.
DR AlphaFoldDB; A9CS97; -.
DR STRING; 481877.A9CS97; -.
DR VEuPathDB; MicrosporidiaDB:EBI_21983; -.
DR HOGENOM; CLU_000688_2_2_1; -.
DR InParanoid; A9CS97; -.
DR OMA; DHEPCVI; -.
DR OrthoDB; 360215at2759; -.
DR Proteomes; UP000001742; Unassembled WGS sequence.
DR GO; GO:0008540; C:proteasome regulatory particle, base subcomplex; IEA:UniProt.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041569; AAA_lid_3.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR003960; ATPase_AAA_CS.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032501; Prot_ATP_ID_OB_2nd.
DR PANTHER; PTHR23073; 26S PROTEASOME REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR23073:SF155; 26S PROTEASOME REGULATORY SUBUNIT 10B; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF17862; AAA_lid_3; 1.
DR Pfam; PF16450; Prot_ATP_ID_OB_C; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00674; AAA; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU003651};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000313|EMBL:EDQ31232.1};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU003651};
KW Proteasome {ECO:0000256|ARBA:ARBA00022942, ECO:0000313|EMBL:EDQ31232.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001742}.
FT DOMAIN 166..305
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT COILED 8..52
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 388 AA; 43864 MW; B46C82F47AFBE528 CRC64;
MPTKEEALES YYKAVQQHEL TLETLKEERE VLKQVNREFN KSERDLKAMQ TIGQNIGEIL
QEITTEKYIV KTSHGPRYVV GCAKDIDRSK LKLGTRVSLD VVTLTIMKIL SREVDPTIFA
MTEATKTYGL DFSSIGGLED QIREIREVIE LPIKNPEIFK RIGIQPPKGV LLYGPPGTGK
TLLAKIVAST MDVTFIKVVA SSLIEKYIGE SAKMVREMFA YARLKAPCII FLDEIDAIGG
ARTNESNSSD REVQRTLMEL LNQLDGFSDL DGVKVIMATN RPDILDSALL RPGRLDRKIE
IPLPNEHGRK EILKIHSKNM NQDQIDLDTI VKMSSGFNGA DLRNVCTEAG MIALRDDRDY
VINDDFIKSV RKISENKKLE TKLDYKKR
//
