ID A9CT40_ENTBH Unreviewed; 609 AA.
AC A9CT40;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Phosphate regulated protein {ECO:0000313|EMBL:EDQ31049.1};
GN ORFNames=EBI_23261 {ECO:0000313|EMBL:EDQ31049.1};
OS Enterocytozoon bieneusi (strain H348) (Microsporidian parasite).
OC Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Enterocytozoonidae;
OC Enterocytozoon.
OX NCBI_TaxID=481877 {ECO:0000313|EMBL:EDQ31049.1, ECO:0000313|Proteomes:UP000001742};
RN [1] {ECO:0000313|EMBL:EDQ31049.1, ECO:0000313|Proteomes:UP000001742}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H348 {ECO:0000313|EMBL:EDQ31049.1,
RC ECO:0000313|Proteomes:UP000001742};
RX PubMed=18060071; DOI=10.1371/journal.pone.0001277;
RA Corradi N., Akiyoshi D.E., Morrison H.G., Feng X., Weiss L.M., Tzipori S.,
RA Keeling P.J.;
RT "Patterns of genome evolution among the microsporidian parasites
RT Encephalitozoon cuniculi, Antonospora locustae and Enterocytozoon
RT bieneusi.";
RL PLoS ONE 2:E1277-E1277(2007).
RN [2] {ECO:0000313|EMBL:EDQ31049.1, ECO:0000313|Proteomes:UP000001742}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H348 {ECO:0000313|EMBL:EDQ31049.1,
RC ECO:0000313|Proteomes:UP000001742};
RX PubMed=19132089; DOI=10.1371/journal.ppat.1000261;
RA Akiyoshi D.E., Morrison H.G., Lei S., Feng X., Zhang Q., Corradi N.,
RA Mayanja H., Tumwine J.K., Keeling P.J., Weiss L.M., Tzipori S.;
RT "Genomic survey of the non-cultivatable opportunistic human pathogen,
RT Enterocytozoon bieneusi.";
RL PLoS Pathog. 5:E1000261-E1000261(2009).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Vacuole membrane
CC {ECO:0000256|ARBA:ARBA00004128}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004128}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDQ31049.1}.
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DR EMBL; ABGB01000004; EDQ31049.1; -; Genomic_DNA.
DR RefSeq; XP_001827737.1; XM_001827685.1.
DR AlphaFoldDB; A9CT40; -.
DR STRING; 481877.A9CT40; -.
DR VEuPathDB; MicrosporidiaDB:EBI_23261; -.
DR HOGENOM; CLU_009308_1_0_1; -.
DR InParanoid; A9CT40; -.
DR OMA; AGGKQQN; -.
DR OrthoDB; 11387at2759; -.
DR Proteomes; UP000001742; Unassembled WGS sequence.
DR GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
DR CDD; cd07751; PolyPPase_VTC4_like; 1.
DR Gene3D; 3.20.100.30; VTC, catalytic tunnel domain; 1.
DR InterPro; IPR003807; DUF202.
DR InterPro; IPR004331; SPX_dom.
DR InterPro; IPR018966; VTC_domain.
DR InterPro; IPR042267; VTC_sf.
DR PANTHER; PTHR46140; VACUOLAR TRANSPORTER CHAPERONE 1-RELATED; 1.
DR PANTHER; PTHR46140:SF1; VACUOLAR TRANSPORTER CHAPERONE 4; 1.
DR Pfam; PF02656; DUF202; 1.
DR Pfam; PF09359; VTC; 1.
DR PROSITE; PS51382; SPX; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001742};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Vacuole {ECO:0000256|ARBA:ARBA00022554}.
FT TRANSMEM 515..535
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 542..564
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 584..602
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..119
FT /note="SPX"
FT /evidence="ECO:0000259|PROSITE:PS51382"
SQ SEQUENCE 609 AA; 71780 MW; 89724D3B26D6FAB2 CRC64;
MGFSEYLANN KNKKYQDKYL EYDAIITAIN NGHDGVEDYI HSEFEKIFSF IKDQTNKFRE
ALISYEKNSE GRNKEIFDLL QEDMKEFAEF IRITIIGFKK ILKHHDKKSS IKLETKYKTI
LKEKLEAINH LDELIYSGSR LKLKEMDINT TSNTNLVFVR KTNKYWVHID NLMALKLSIV
KNLPLYVFTN EKGQTPYSAW NHKTHDTCVT SVYFDNDDFY IYDGRLKKNE GAEAIRIRWY
GTISKETDTV FIERKKHCEG WTGEESKKLR FKIEEKYVND FIQGKDVWKH VSRLNGKEIK
YLYDEIQGAI VKHTLKPKIR TFYKRISFQI PNDSTIRLSL DTNLCMIKEN GENWRRTDIM
CEWPFRQLED TEIVRFPHAI LEVKTQGVDE SKPTWLEDIL NSTYVEHVYK FSKFLHGIAI
LYNVKDIPYW LPQMKTDIRK DPFINIRNRK KFNNDELILV SSQTDCCKSI ELTNSIESNN
LKFDNRTNNN NNTDFRISIP VRVEPKVFFA NERTFLSWVQ FAIFLGGIGT AMLGLENYKA
NLCGSLLIGV AIIFALYALH LFFWRAERIR QKDPGPYDDT KGPLILVGVF ILALLFSVYF
KFPMKKKYE
//
