ID   A9CWL8_HOEPD            Unreviewed;       395 AA.
AC   A9CWL8;
DT   05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 2.
DT   24-JAN-2024, entry version 39.
DE   RecName: Full=Beta-lactamase class A catalytic domain-containing protein {ECO:0000259|Pfam:PF13354};
GN   ORFNames=HPDFL43_20127 {ECO:0000313|EMBL:EDQ35538.2};
OS   Hoeflea phototrophica (strain DSM 17068 / NCIMB 14078 / DFL-43).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Phyllobacteriaceae; Hoeflea.
OX   NCBI_TaxID=411684 {ECO:0000313|EMBL:EDQ35538.2, ECO:0000313|Proteomes:UP000004291};
RN   [1] {ECO:0000313|EMBL:EDQ35538.2, ECO:0000313|Proteomes:UP000004291}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DFL-43 {ECO:0000313|EMBL:EDQ35538.2,
RC   ECO:0000313|Proteomes:UP000004291};
RA   Wagner-Dobler I., Ferriera S., Johnson J., Kravitz S., Beeson K.,
RA   Sutton G., Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL   Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:EDQ35538.2, ECO:0000313|Proteomes:UP000004291}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DFL-43 {ECO:0000313|EMBL:EDQ35538.2,
RC   ECO:0000313|Proteomes:UP000004291};
RA   Fiebig A.;
RL   Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EDQ35538.2}.
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DR   EMBL; ABIA03000001; EDQ35538.2; -; Genomic_DNA.
DR   AlphaFoldDB; A9CWL8; -.
DR   STRING; 411684.HPDFL43_20127; -.
DR   eggNOG; COG2367; Bacteria.
DR   HOGENOM; CLU_042385_0_0_5; -.
DR   OrthoDB; 108135at2; -.
DR   Proteomes; UP000004291; Chromosome.
DR   GO; GO:0008800; F:beta-lactamase activity; IEA:InterPro.
DR   GO; GO:0030655; P:beta-lactam antibiotic catabolic process; IEA:InterPro.
DR   GO; GO:0046677; P:response to antibiotic; IEA:InterPro.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR045155; Beta-lactam_cat.
DR   InterPro; IPR000871; Beta-lactam_class-A.
DR   PANTHER; PTHR35333; BETA-LACTAMASE; 1.
DR   PANTHER; PTHR35333:SF4; SLR0121 PROTEIN; 1.
DR   Pfam; PF13354; Beta-lactamase2; 1.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000004291}.
FT   DOMAIN          148..242
FT                   /note="Beta-lactamase class A catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF13354"
SQ   SEQUENCE   395 AA;  43374 MW;  0F908097C5F818E8 CRC64;
     MKGTLWLMLC VSVSGGMGCG GMAKAHAGEM EIERLEQVFG APTLEETLFS ARFLMAVPTK
     RLQSIIRDVE DRYGEMLSVR QDSERYLVET ETHSIPVEIK LDQDGLIVGL LIKPAEPKTA
     SFEETLAAIA ATPGEVSYLV RRENVPDFAL SAERRLAVGS AFKLGVLAVL MDDLNAGRRS
     WDDVMRLEER DRSLPSGRLQ DFPSGAPFTL HTLAAAMIAE SDNTATDMLI RLLGRDRIAE
     RLGLNTLLTT RAFFHLKADP ELAARYAAGN SQERLILLED LEWRKLPEVE DVTGPHHQGV
     EWYVPVEQLC ELAIEVAHLD IFTLNPGPVR TANWNRVAYK GGSEPGVLNL TAALRHADGD
     TSCISVSVNA ETPIDETAVS SLFARLASQL SEPLP
//