ID A9DBT9_HOEPD Unreviewed; 413 AA.
AC A9DBT9;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 24-JAN-2024, entry version 53.
DE SubName: Full=Precorrin-6y C5,15-methyltransferase, CbiE subunit {ECO:0000313|EMBL:EDQ32290.1};
DE EC=2.1.1.132 {ECO:0000313|EMBL:EDQ32290.1};
GN ORFNames=HPDFL43_12513 {ECO:0000313|EMBL:EDQ32290.1};
OS Hoeflea phototrophica (strain DSM 17068 / NCIMB 14078 / DFL-43).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Phyllobacteriaceae; Hoeflea.
OX NCBI_TaxID=411684 {ECO:0000313|EMBL:EDQ32290.1, ECO:0000313|Proteomes:UP000004291};
RN [1] {ECO:0000313|EMBL:EDQ32290.1, ECO:0000313|Proteomes:UP000004291}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DFL-43 {ECO:0000313|EMBL:EDQ32290.1,
RC ECO:0000313|Proteomes:UP000004291};
RA Wagner-Dobler I., Ferriera S., Johnson J., Kravitz S., Beeson K.,
RA Sutton G., Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EDQ32290.1, ECO:0000313|Proteomes:UP000004291}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DFL-43 {ECO:0000313|EMBL:EDQ32290.1,
RC ECO:0000313|Proteomes:UP000004291};
RA Fiebig A.;
RL Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004953}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDQ32290.1}.
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DR EMBL; ABIA03000004; EDQ32290.1; -; Genomic_DNA.
DR RefSeq; WP_007198273.1; NZ_CM002917.1.
DR AlphaFoldDB; A9DBT9; -.
DR STRING; 411684.HPDFL43_12513; -.
DR eggNOG; COG2241; Bacteria.
DR eggNOG; COG2242; Bacteria.
DR HOGENOM; CLU_031955_0_0_5; -.
DR OrthoDB; 9787825at2; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000004291; Chromosome.
DR GO; GO:0046025; F:precorrin-6Y C5,15-methyltransferase (decarboxylating) activity; IEA:UniProtKB-EC.
DR GO; GO:0008276; F:protein methyltransferase activity; IEA:InterPro.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd11644; Precorrin-6Y-MT; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR000878; 4pyrrol_Mease.
DR InterPro; IPR035996; 4pyrrol_Methylase_sf.
DR InterPro; IPR014777; 4pyrrole_Mease_sub1.
DR InterPro; IPR014776; 4pyrrole_Mease_sub2.
DR InterPro; IPR012818; CbiE.
DR InterPro; IPR006365; Cbl_synth_CobL.
DR InterPro; IPR014008; Cbl_synth_MTase_CbiT.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR02467; CbiE; 1.
DR NCBIfam; TIGR02469; CbiT; 1.
DR PANTHER; PTHR43182; COBALT-PRECORRIN-6B C(15)-METHYLTRANSFERASE (DECARBOXYLATING); 1.
DR PANTHER; PTHR43182:SF1; COBALT-PRECORRIN-7 C(5)-METHYLTRANSFERASE; 1.
DR Pfam; PF00590; TP_methylase; 1.
DR PIRSF; PIRSF036428; CobL; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF53790; Tetrapyrrole methylase; 1.
PE 4: Predicted;
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:EDQ32290.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000004291};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EDQ32290.1}.
FT DOMAIN 13..198
FT /note="Tetrapyrrole methylase"
FT /evidence="ECO:0000259|Pfam:PF00590"
SQ SEQUENCE 413 AA; 43693 MW; BEB337A038E3787E CRC64;
MGEIGTAGAT PWLTLIGIGD NGLDSLTQPA RALFESARTI IAPQRVLDRI DCGEREVIAW
TFGIRQTLEL LMARRGTPTT ILATGDPMHF GIGATLMRDL DASEMRVIPS PSAFSLAASR
LGWGLQDVTQ ISLHGRSVHG LASHVQPGAR IIALTSTGRT VIEAAEILNA RGYGRSGMWV
LEHMGGPDER VRVMRAEQVV AEKPAIADFN TLAIACEPTP GAALLSAVPG LPDAAFEHDG
QLTKREVRAV TLARLGPVPG GLLWDVGAGC GSVGIEWMRA ARGAHAIAIE PVEKRRTMIA
QNAIDLGAPG LEIVAGNAPD ALANLKRPDA VFIGGGISHA GVFEAVWDAL KPMGRLVANA
VTVEGEARLF ALQAEHGGEL VRLQTSRAEP VGRYLGWKPL MPVTIWSVTK EGS
//
