ID A9EAA7_9FLAO Unreviewed; 3908 AA.
AC A9EAA7;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 83.
DE SubName: Full=Polyketide synthase of type I {ECO:0000313|EMBL:EDP94607.1};
GN ORFNames=KAOT1_04300 {ECO:0000313|EMBL:EDP94607.1};
OS Kordia algicida OT-1.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Kordia.
OX NCBI_TaxID=391587 {ECO:0000313|EMBL:EDP94607.1, ECO:0000313|Proteomes:UP000002945};
RN [1] {ECO:0000313|EMBL:EDP94607.1, ECO:0000313|Proteomes:UP000002945}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OT-1 {ECO:0000313|EMBL:EDP94607.1,
RC ECO:0000313|Proteomes:UP000002945};
RX PubMed=21622754; DOI=10.1128/JB.05241-11;
RA Lee H.S., Kang S.G., Kwon K.K., Lee J.H., Kim S.J.;
RT "Genome sequence of the algicidal bacterium Kordia algicida OT-1.";
RL J. Bacteriol. 193:4031-4032(2011).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDP94607.1}.
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DR EMBL; ABIB01000015; EDP94607.1; -; Genomic_DNA.
DR RefSeq; WP_007093431.1; NZ_DS544873.1.
DR STRING; 391587.KAOT1_04300; -.
DR eggNOG; COG3321; Bacteria.
DR HOGENOM; CLU_000022_58_6_10; -.
DR OrthoDB; 1230081at2; -.
DR Proteomes; UP000002945; Unassembled WGS sequence.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR CDD; cd08953; KR_2_SDR_x; 2.
DR CDD; cd00833; PKS; 3.
DR Gene3D; 1.10.1240.100; -; 3.
DR Gene3D; 3.40.47.10; -; 3.
DR Gene3D; 3.40.630.30; -; 1.
DR Gene3D; 1.10.1200.10; ACP-like; 3.
DR Gene3D; 3.10.129.10; Hotdog Thioesterase; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR Gene3D; 3.10.129.110; Polyketide synthase dehydratase; 1.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR InterPro; IPR000182; GNAT_dom.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR032821; PKS_assoc.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR042104; PKS_dehydratase_sf.
DR InterPro; IPR049552; PKS_DH_N.
DR InterPro; IPR013968; PKS_KR.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR43775:SF37; FATTY ACID SYNTHASE; 1.
DR Pfam; PF16197; KAsynt_C_assoc; 3.
DR Pfam; PF00109; ketoacyl-synt; 3.
DR Pfam; PF02801; Ketoacyl-synt_C; 3.
DR Pfam; PF08659; KR; 2.
DR Pfam; PF21089; PKS_DH_N; 2.
DR Pfam; PF00550; PP-binding; 3.
DR SMART; SM00822; PKS_KR; 2.
DR SMART; SM00825; PKS_KS; 3.
DR SMART; SM00823; PKS_PP; 3.
DR SMART; SM01294; PKS_PP_betabranch; 1.
DR SUPFAM; SSF47336; ACP-like; 3.
DR SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
DR SUPFAM; SSF53901; Thiolase-like; 3.
DR PROSITE; PS50075; CARRIER; 3.
DR PROSITE; PS51186; GNAT; 1.
DR PROSITE; PS00606; KS3_1; 2.
DR PROSITE; PS52004; KS3_2; 3.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000002945};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 202..394
FT /note="N-acetyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS51186"
FT DOMAIN 419..496
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 521..940
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT DOMAIN 1564..1637
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 1683..2117
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT DOMAIN 3039..3113
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 3183..3606
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
SQ SEQUENCE 3908 AA; 434441 MW; 44431EAAE3BDAC50 CRC64;
MISEKYLNDL RSAITEIFNQ SLNQQPQIIV NLGCKDGTVL REIYQTISGS TLRGKYLKEH
PVQCYAVDAS QENLDNLALD NKNIQTFLGD IQTSNGLKKA LKNIGISSDK KILYLHTVTP
TANWQAYLQV YADHLQNNQL LFTSEHVVAE TQASLDKNQI TTEKFITLAA NIGLFTEKLS
KRYPDSKTNK EVALHNITKR AYSIRNASLK DLQTLDTLEE LCWQSHIRSS KEAIQQRIKT
FPQGQFVLEK NGEVVGVIYS QAINDKAQLE KATMDNVHKL HNANGNVMQL LAVNIHPSVQ
LFNYGDQLLE FMLQRCSLIN KVTEIVAVSI CKNYDKNGEY SFEEYLNLQG EKQDPIMAFH
HNHGANIVKG LANYRERDTA NEGFGVLVHY TNLDERINTN KAFVASPETI SKNTSSEFTK
KETTQKFITE TIANLLNINT ETVDEEQPLM EMGLNSVDLQ MLQRQIEKKI NQQLEAGFFF
EYNTVLKVAE KIQADFTINN TEKPTETTNT AKANVKNNVS DTDIAIIGIS CKLPGNITSV
DALWEALTEE KSLISSYPKE RGNWANSEEF KGIDQGGFMQ NAAAFDASFF RISPKEAQIT
DPQQRILLEL AWACLEDAGI PAKKLIGSNT GVFVGASNAD YSRKVQDAKL AIEAHHAVGS
SLAILANRLS YYFDLSGPSL LVDTACSSSL VAIHSAVQSL HSGECDSAIV GGVNFICHPD
LSIAYHKAGM LSPEAKCKVF DSKANGYVRG EGTVVMLLKP LKKAIEDKNQ IHGVIKGSAI
NHGGLAAGLT VPNPKKQSEL LVNAWKNANI STSDLSYIEA HGTGTSLGDP IEVQGIKNAL
TTHSDSKTLE KCTIGSIKSN VGHLESAAGM TGMLKVILAM KHKQLPASIH FSTLNPKINL
NDSPIQIQNT LTSWQSEKPL LAGVSSFGSG GTNGHVVLEE FQQKTKQNHS TNNESLFVLS
AKNEDRLIAY AEKIIRWIDT SSETFNFNDA IYSWQVGRTA MKKRLAIQAT NFQDLKEKLS
QWIAGKTVET TWSSSNAATN YTEEIIAKAI SEKNISLLGQ IWTTGATINW EAYYANQNDL
AFVSLPTYPF AKDHYWIQET ETITETKQPT KTTNSKLYAT PTWKAIPIEN IAESNSKEVT
ETHILLCGFS TLLSKKLSQE LPETTISTIN SKKKKIAKTY TEIAVECFEE IQQIVREKSN
KKIDLWIVVP ALTTHTTWLG LSGMLQTLHA EYPSVSGQVL AVNPKIKTPE LTQKLLENQS
VTTELTVKYD ANERKVIRWE AIQESSNEQT TVFKDEGVYI LTGGLGGLGT IFIKEIGKQT
KNATIIITGR SELTADKQEK IKQLATISKN IHYHKVTLTS NDEVKTFINS IKEKHGNING
IIHCAGMVKD NFIIKKTASE FEEVLQPKVA GTIHLDEATK NENLDFFVLF SSIFSVVGNV
GQADYATANG FMDQFAAYRN TLLAQKERAG QTLSINWPFW KDGGMDIHES SLAIIKEETG
MIPMETATGL HAFYQGIANK YNQLLVMEGV EEKLVKTLEN LAPTNETIEQ AQDYSVENQD
VIFEKTLQKT KELFGEVLGF APSKVDEHES FSAYGIDSIF INQLNQKLSK TFDSLSKTIF
FEHQTLHEIT NYLVNEYTET CASWTQTDIN QTQKGSSKIF KDASKTGQTI KNTDEAEKQI
NHKEPIAIIG ISGIYPEAKD LDEFWENLQE GKNSISEIPP SRWSLDDFYE PDMQKAVKEG
KSYAKWGGFI NEFAQFDPMF FGISPREALN IDPHERLFLQ ESWRALESSG YTKHDLKQKY
HQKVGVFAGV TKTGFELKAP FYRNDNHKFH PRSSFSSVAN RLSYVLDIKG PSMPIDTMCS
SSLTAIHEAC EHIHRGECEV AFAGGVNLYL HPSTYSYLSS QHMLSVDGQC KSFGLGGNGF
VPGEGVGVVL LKPLSEAVKD NDVIHGVILS THVNHGGKTN GYTVPSPVSQ SQLIKTAIKK
AGINARDISY IEAHGTGTEL GDPIEVEGLK KAFDADTTDK NYCAIGSVKS NIGHLEAAAG
ISGLTKVLLQ MKHGKIVPSL HTEDLNPNID FEKTAFQVAT DLQNWERPFV QNEEKPRIAG
ISSFGAGGAN AHVILQEYQP QEKASFATES LLAEAEKVLI PLSARNKAQL KLRAVALLDA
LRKNNNASQF DLISLTYTLQ VGREAMDERL GFIVSSIEEL EEKLIQYINE AKEIENFDQG
NKNYPDKTFK LLTKEAEFQQ TIARWVKDKK LANLLMLWVN GLTIDWHQFY DTDVNISRVA
LPTYPFANDE YWIQTESIEK GFTKISEGAE HINALLHHNT SNIYEQRYTS RFNGDEFFLK
TQYNADEKIT EKIVPTFTCI EMARLAALHA TSGNESETTL TLQNLIWSTP FTLSEKKEIN
IALTATAPLR EENIALHFDI FSESDGDETV HCQGKAVLSD HSLPQKHNIQ ELLTQLEEHT
ISNHYKGVQE IHKTDGKLVA TIDFSEEILQ QQETLILHPK TLSYIQNILA EFEHKMSNAY
IIGCDAVQII QPLQEEACII ISFVEESLFS DDICTLNIDI CDTLGNVCVQ FVGCSFGKQS
ETLTATTEAT ETEKLFFTPQ WQETKVEGTQ KRDVAQYHTI LLDLPQIKTT QLETAIGNNV
CTNISLKKEN LHAQYHQYAT ACFEYIKNLQ KEKFIGNQHI WFVIPNTEQY APLQGVYGLL
RTAMLENPKI SGQILLTDAH VSQNNLAQQL NAQTVRNTDL IVKHENKKQY VFQWQQQSLQ
TSNEIVYKDQ GIYVITGGLG GLGTIFCKEI LQKTTNATVI LTGRSELTQT KKDAIAKLKS
YGGTVIYKSV NIADEKAVHN FFENVLKSHQ QINGILHCAG MISDNFIAEK TTEEFHQVLM
PKVDGTIYID NATAEIELDF LVYFSSIAGA IGFVGQADYA SANSFMDHYA YYRNGLVQKG
KRHGKTLSIN WPLWKDGGMG IDKATEKMVA QTIGMQSLAT KTGLKAFYTS LQSDCSQSLV
VEGNGNKIKS HVFNLKKSAQ TTQDATISEN IVESNYTVEN TQETLKGILT EILGIQSSAL
SMEQTFVDMG LNSILGVELA IAINNTFGTA ISNVIVYDYP NIKELSSYVN SHLLKNTSIA
KKSIATISKE VKAVAKIDTE NLINFGEKYP KLTRRKVTNL TNLYGNITPA YGYSTQKSSA
TTDDKIAIVG MSGKYPKAKN LKEYWNNLEN GVDAVTEIPN SRWNIDKYYD PDPEKEGKIY
AKWMGMLDEV DLFDPLFFKI SPQEATYMDP EHRLFLQEGY KAFEDAGYAG EALKDIKCGV
YLGLERSEYS WHLRQNNAMS PNVTSNNSAI AAARIAYFLN LKGPAITIDT ACSSSLVAMH
LACKSLLNNE IDMALTGGVR LWLGPETYQG MCQARMLSPD GKCKTFDDSA NGFVPGEGVG
AVVLKRLKDA EADNDNILGV ILGSGINQDG KTNGITAPSV KSQIALEQEV YAQNNIDPST
ITYVEAHGTG TKLGDPIELQ ALSTVFGEST DKKNYCALGS VKSNIGHTTA AAGIAGVHKV
LLSLQNQTLA PTLHVTKENS HFDFNNSPFY VNTEKRVWKT NPHSLRRASV SSFGFSGTNS
HLVIEEYPKT TNQATSETKS VIIPLSAKTT AQLKEKAADL LAFISEQNKA EASEENTNTL
DLGSIAYTLQ IGRDDMRERL GFVVNSIDQL ENKLQAYLNG NDSDNEIYTG KATTQNDTLS
LFSTDTDLQE AVSNWIQNGK LEKLLKLWVN GLTISWSKFY ENTKPKRVSL PTYPFAKEKY
WVTSQNGEAA TNHSGVTATI HPLVHTNTSN LNQQSFTSTF SGNEFFLKEH LVHGKAILPG
VAYLEMIRVA IEKSVPNLSD EYEISLQNIF WIRPLTVETT TEIEITVTPN DDATIAFEIV
TKMKKKIV
//
