ID A9F0F9_SORC5 Unreviewed; 402 AA.
AC A9F0F9;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE SubName: Full=RND family efflux transporter {ECO:0000313|EMBL:CAN91267.1};
GN Name=mdtA1 {ECO:0000313|EMBL:CAN91267.1};
GN OrderedLocusNames=sce1110 {ECO:0000313|EMBL:CAN91267.1};
OS Sorangium cellulosum (strain So ce56) (Polyangium cellulosum (strain So
OS ce56)).
OC Bacteria; Myxococcota; Polyangia; Polyangiales; Polyangiaceae; Sorangium.
OX NCBI_TaxID=448385 {ECO:0000313|EMBL:CAN91267.1, ECO:0000313|Proteomes:UP000002139};
RN [1] {ECO:0000313|EMBL:CAN91267.1, ECO:0000313|Proteomes:UP000002139}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=So ce56 {ECO:0000313|Proteomes:UP000002139};
RX PubMed=17965706; DOI=10.1038/nbt1354;
RA Schneiker S., Perlova O., Kaiser O., Gerth K., Alici A., Altmeyer M.O.,
RA Bartels D., Bekel T., Beyer S., Bode E., Bode H.B., Bolten C.J.,
RA Choudhuri J.V., Doss S., Elnakady Y.A., Frank B., Gaigalat L., Goesmann A.,
RA Groeger C., Gross F., Jelsbak L., Jelsbak L., Kalinowski J., Kegler C.,
RA Knauber T., Konietzny S., Kopp M., Krause L., Krug D., Linke B., Mahmud T.,
RA Martinez-Arias R., McHardy A.C., Merai M., Meyer F., Mormann S.,
RA Munoz-Dorado J., Perez J., Pradella S., Rachid S., Raddatz G., Rosenau F.,
RA Rueckert C., Sasse F., Scharfe M., Schuster S.C., Suen G.,
RA Treuner-Lange A., Velicer G.J., Vorholter F.-J., Weissman K.J., Welch R.D.,
RA Wenzel S.C., Whitworth D.E., Wilhelm S., Wittmann C., Bloecker H.,
RA Puehler A., Mueller R.;
RT "Complete genome sequence of the myxobacterium Sorangium cellulosum.";
RL Nat. Biotechnol. 25:1281-1289(2007).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; AM746676; CAN91267.1; -; Genomic_DNA.
DR RefSeq; WP_012233744.1; NC_010162.1.
DR AlphaFoldDB; A9F0F9; -.
DR STRING; 448385.sce1110; -.
DR KEGG; scl:sce1110; -.
DR eggNOG; COG0845; Bacteria.
DR HOGENOM; CLU_018816_14_4_7; -.
DR OrthoDB; 176710at2; -.
DR BioCyc; SCEL448385:SCE_RS05800-MONOMER; -.
DR Proteomes; UP000002139; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR039562; MFP_biotin_lipoyl_2.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469:SF15; HLYD FAMILY OF SECRETION PROTEINS; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF13533; Biotin_lipoyl_2; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000002139}.
FT DOMAIN 59..105
FT /note="Membrane fusion protein biotin-lipoyl like"
FT /evidence="ECO:0000259|Pfam:PF13533"
FT DOMAIN 160..318
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT COILED 98..178
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 402 AA; 42647 MW; 4034F1AA7D1C5417 CRC64;
MRTLLRRPGL WILIALLAAF TIVMAVRARG PKVKVAVAAR KDLEQRVVAS GRVRVPTRVQ
VAAQVSGLVV AVGAIEGQRV KAGDLLVQID DAEARAAVSQ AKAAVDQASA RVEQLRRVGA
IVATEALRQA ETNLERTEVE LARVRELSAS GAVAQAELDN ARQSVELARA QKVAAEAQRI
ASTPMGADSR VALTALLQAQ AQHVGATVRL AQTRIVAHQD GVVLTRSVEP GDVVQPARTL
IVLAADGSPQ LVFQPDERNL AWIALGQKAR ASADAYPQQV FDAEVSYIAP SIDPQRGSVE
VRLAVPSAPA FLLPDMTVSI DLSVARRESA LVVPSDAVRD AATPAPWLFA VEDNRLVRKD
VKLGIRGEGA VEVVEGLGEG SVVVLPDGRI HAPGQRVRAE LD
//
