ID A9GK09_SORC5 Unreviewed; 638 AA.
AC A9GK09;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Mechanosensitive channel protein {ECO:0000313|EMBL:CAN96514.1};
GN OrderedLocusNames=sce6347 {ECO:0000313|EMBL:CAN96514.1};
OS Sorangium cellulosum (strain So ce56) (Polyangium cellulosum (strain So
OS ce56)).
OC Bacteria; Myxococcota; Polyangia; Polyangiales; Polyangiaceae; Sorangium.
OX NCBI_TaxID=448385 {ECO:0000313|EMBL:CAN96514.1, ECO:0000313|Proteomes:UP000002139};
RN [1] {ECO:0000313|EMBL:CAN96514.1, ECO:0000313|Proteomes:UP000002139}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=So ce56 {ECO:0000313|Proteomes:UP000002139};
RX PubMed=17965706; DOI=10.1038/nbt1354;
RA Schneiker S., Perlova O., Kaiser O., Gerth K., Alici A., Altmeyer M.O.,
RA Bartels D., Bekel T., Beyer S., Bode E., Bode H.B., Bolten C.J.,
RA Choudhuri J.V., Doss S., Elnakady Y.A., Frank B., Gaigalat L., Goesmann A.,
RA Groeger C., Gross F., Jelsbak L., Jelsbak L., Kalinowski J., Kegler C.,
RA Knauber T., Konietzny S., Kopp M., Krause L., Krug D., Linke B., Mahmud T.,
RA Martinez-Arias R., McHardy A.C., Merai M., Meyer F., Mormann S.,
RA Munoz-Dorado J., Perez J., Pradella S., Rachid S., Raddatz G., Rosenau F.,
RA Rueckert C., Sasse F., Scharfe M., Schuster S.C., Suen G.,
RA Treuner-Lange A., Velicer G.J., Vorholter F.-J., Weissman K.J., Welch R.D.,
RA Wenzel S.C., Whitworth D.E., Wilhelm S., Wittmann C., Bloecker H.,
RA Puehler A., Mueller R.;
RT "Complete genome sequence of the myxobacterium Sorangium cellulosum.";
RL Nat. Biotechnol. 25:1281-1289(2007).
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DR EMBL; AM746676; CAN96514.1; -; Genomic_DNA.
DR AlphaFoldDB; A9GK09; -.
DR STRING; 448385.sce6347; -.
DR KEGG; scl:sce6347; -.
DR eggNOG; COG0668; Bacteria.
DR HOGENOM; CLU_025726_0_0_7; -.
DR Proteomes; UP000002139; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.10.287.1260; -; 1.
DR Gene3D; 2.30.30.60; -; 1.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR PANTHER; PTHR30566:SF25; INNER MEMBRANE PROTEIN-RELATED; 1.
DR PANTHER; PTHR30566; YNAI-RELATED MECHANOSENSITIVE ION CHANNEL; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002139};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 100..121
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 279..303
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 410..427
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 433..452
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 455..521
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
FT REGION 30..52
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 638 AA; 67939 MW; BAC07C3F3716F5BF CRC64;
MTVVQRTSGD LRLNPHLHAV FLDGATTKTA QSSCGTSSRG AAAVPPDRRR RAPRSSLFDF
KAICAKHPGR LGPGRARVPP PCARYQIPEI DEVKRTRSGI AAAALLALLT AMLMFSTRAV
AGPQDGLPPA DADRSTPRRA LRLLIDASRE GRHDVAAYAL DLSAIPRAAQ AERGPELAAQ
LTFVLEQRLW NAWEELSDEP EGNPADGPGR DEVGRIPLGD TAIPIVLSRA AGPGGAPIWL
VSRSTIAAVP ELHEAFGPGP IAERLPAVLS RVRFLGLAAW QWLGLVAAIA ASSLGGLLLG
RLVSVAAGRL VRRTEVQWDD RLLDGLRTPL RALLTLALAS GLVRPLRLAA PAQEIVDTLL
QTLLITAAAW LTTCLVRFAG DTVTERVTAS VTDMALARGS KTRVAMLRRI ANALVGVVAV
ALVLLQFDVV RKVGVSLLAS AGIAGVVVGF AAQKSIATLL AGLQLSFSQP IRIGDTVIVE
GEWGWIEEIT LTFVVVKVWD LRRLVVPITY FLEKPFQNWT KESPDLLGTV FVHADYTVPI
DEMRAEVARL CAANANWDGK VAGLVVVDAT AQTIALRALV SAAESGKLWD LRCAVREGLI
KRLTSLEGGR YLPRARVALE GEGEPRGASG PTGGIASV
//
