ID A9HI64_GLUDA Unreviewed; 874 AA.
AC A9HI64;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE SubName: Full=Putative Na+/H+ antiporter {ECO:0000313|EMBL:CAP55727.1};
GN OrderedLocusNames=GDI1784 {ECO:0000313|EMBL:CAP55727.1};
OS Gluconacetobacter diazotrophicus (strain ATCC 49037 / DSM 5601 / CCUG 37298
OS / CIP 103539 / LMG 7603 / PAl5).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Acetobacteraceae; Gluconacetobacter.
OX NCBI_TaxID=272568 {ECO:0000313|EMBL:CAP55727.1, ECO:0000313|Proteomes:UP000001176};
RN [1] {ECO:0000313|EMBL:CAP55727.1, ECO:0000313|Proteomes:UP000001176}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49037 / DSM 5601 / CCUG 37298 / CIP 103539 / LMG 7603 /
RC PAl5 {ECO:0000313|Proteomes:UP000001176};
RX PubMed=19775431; DOI=10.1186/1471-2164-10-450;
RA Bertalan M., Albano R., Padua V., Rouws L., Rojas C., Hemerly A.,
RA Teixeira K., Schwab S., Araujo J., Oliveira A., Franca L., Magalhaes V.,
RA Alqueres S., Cardoso A., Almeida W., Loureiro M.M., Nogueira E., Cidade D.,
RA Oliveira D., Simao T., Macedo J., Valadao A., Dreschsel M., Freitas F.,
RA Vidal M., Guedes H., Rodrigues E., Meneses C., Brioso P., Pozzer L.,
RA Figueiredo D., Montano H., Junior J., Filho G., Flores V., Ferreira B.,
RA Branco A., Gonzalez P., Guillobel H., Lemos M., Seibel L., Macedo J.,
RA Alves-Ferreira M., Sachetto-Martins G., Coelho A., Santos E., Amaral G.,
RA Neves A., Pacheco A.B., Carvalho D., Lery L., Bisch P., Rossle S.C.,
RA Urmenyi T., Kruger W.V., Martins O., Baldani J.I., Ferreira P.C.;
RT "Complete genome sequence of the sugarcane nitrogen-fixing endophyte
RT Gluconacetobacter diazotrophicus Pal5.";
RL BMC Genomics 10:450-450(2009).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AM889285; CAP55727.1; -; Genomic_DNA.
DR RefSeq; WP_012225295.1; NC_010125.1.
DR AlphaFoldDB; A9HI64; -.
DR KEGG; gdi:GDI1784; -.
DR OrthoDB; 9809206at2; -.
DR Proteomes; UP000001176; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0015385; F:sodium:proton antiporter activity; IEA:InterPro.
DR GO; GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd00038; CAP_ED; 1.
DR Gene3D; 6.10.140.1330; -; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR018422; Cation/H_exchanger_CPA1.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR10110; SODIUM/HYDROGEN EXCHANGER; 1.
DR PANTHER; PTHR10110:SF86; SODIUM_HYDROGEN EXCHANGER 7; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
PE 4: Predicted;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Methionine biosynthesis {ECO:0000256|ARBA:ARBA00023167};
KW Reference proteome {ECO:0000313|Proteomes:UP000001176};
KW Sodium {ECO:0000256|ARBA:ARBA00023053};
KW Sodium transport {ECO:0000256|ARBA:ARBA00023201};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..23
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 35..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 77..94
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 106..129
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 202..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 225..248
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 255..274
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 294..315
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 322..344
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 364..382
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 394..418
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 710..807
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
SQ SEQUENCE 874 AA; 95346 MW; 57E790D7399622F5 CRC64;
MAVTGLAAVL LAIAVLLVIV SAVQPIARRL ELSETVLLAV VGILLGGSAD LVLRSSYTDL
FNGAAETLLD FPLNSEAFLL IFLPALVFQG ALAIDVRRLA HETATVLLLA VVAVVVSTAT
IGLALFPFAS LPLSVCLLLG SIVATTDPSA VAGIFRDIGA TSRLTRLVEG EALLNDAAAI
SIFSILLTAV TSHHPIAPGA ALMDFTLAFS GALVMGVLFG RLTLLLITML GAAPAAEITL
TVALPYIVYI VCDEFLGFSG VVATATAGLT LSVYGPSTFR PQTWRFLNEL WQQLVFWAGS
LVFVLASMLV PRLLVGMTRW DCVLILIATG AGLLARGAVV FGLLPVLAAT RLSPPVPNPF
KVTMVWGGLR GAITLALALA VTENEHVATP VAHFIGIIAT GFVLITLFVN GTTLRYLVVF
LKLDQLSPID QALRHQVLGI GLGEVRDRTH EMAEELGFSR AVAGNVMSML DRRVAEEEQA
NTFDTALADR QRVTLALIVV ANKERSILLD LFRIQGLSRP VMETLLRSAE AMVDGARLEG
RFGYVRALRR RLRPSMRFRL AQVIHHRFHF DQPLMSCMTE RFEMLMISYF VSLSLIRFMR
TRMEATLGSR ISEIVGEVLE RQRKLLNEAL QTLRLHYHGY SEALESRLLQ QVALRLEGEE
YDALMSESLI SEELHRELSR DVERRRGQLD FKLTFNIKAG IEARLRSLPV FHGLPDEALH
ALAPQMSIHF TSPGERLYHR GRKVRIVYFI SAGVTETHYA EHDVRFGAGD VLGADEALSG
ERVHAVSRSL QFGHFDHMSA RRFRRLVAEY PVIQHNLAEL ARARETSERS EVQLVPTDGD
NTVAPSDEAI ALATASLSDA LPATMGQDSP PSGG
//
