ID A9HN42_GLUDA Unreviewed; 645 AA.
AC A9HN42;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE RecName: Full=acetate--CoA ligase {ECO:0000256|ARBA:ARBA00013275};
DE EC=6.2.1.1 {ECO:0000256|ARBA:ARBA00013275};
GN Name=acsA {ECO:0000313|EMBL:CAP56389.1};
GN OrderedLocusNames=GDI2446 {ECO:0000313|EMBL:CAP56389.1};
OS Gluconacetobacter diazotrophicus (strain ATCC 49037 / DSM 5601 / CCUG 37298
OS / CIP 103539 / LMG 7603 / PAl5).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Acetobacteraceae; Gluconacetobacter.
OX NCBI_TaxID=272568 {ECO:0000313|EMBL:CAP56389.1, ECO:0000313|Proteomes:UP000001176};
RN [1] {ECO:0000313|EMBL:CAP56389.1, ECO:0000313|Proteomes:UP000001176}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49037 / DSM 5601 / CCUG 37298 / CIP 103539 / LMG 7603 /
RC PAl5 {ECO:0000313|Proteomes:UP000001176};
RX PubMed=19775431; DOI=10.1186/1471-2164-10-450;
RA Bertalan M., Albano R., Padua V., Rouws L., Rojas C., Hemerly A.,
RA Teixeira K., Schwab S., Araujo J., Oliveira A., Franca L., Magalhaes V.,
RA Alqueres S., Cardoso A., Almeida W., Loureiro M.M., Nogueira E., Cidade D.,
RA Oliveira D., Simao T., Macedo J., Valadao A., Dreschsel M., Freitas F.,
RA Vidal M., Guedes H., Rodrigues E., Meneses C., Brioso P., Pozzer L.,
RA Figueiredo D., Montano H., Junior J., Filho G., Flores V., Ferreira B.,
RA Branco A., Gonzalez P., Guillobel H., Lemos M., Seibel L., Macedo J.,
RA Alves-Ferreira M., Sachetto-Martins G., Coelho A., Santos E., Amaral G.,
RA Neves A., Pacheco A.B., Carvalho D., Lery L., Bisch P., Rossle S.C.,
RA Urmenyi T., Kruger W.V., Martins O., Baldani J.I., Ferreira P.C.;
RT "Complete genome sequence of the sugarcane nitrogen-fixing endophyte
RT Gluconacetobacter diazotrophicus Pal5.";
RL BMC Genomics 10:450-450(2009).
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DR EMBL; AM889285; CAP56389.1; -; Genomic_DNA.
DR RefSeq; WP_012226453.1; NC_010125.1.
DR AlphaFoldDB; A9HN42; -.
DR KEGG; gdi:GDI2446; -.
DR OrthoDB; 4471305at2; -.
DR Proteomes; UP000001176; Chromosome.
DR GO; GO:0003987; F:acetate-CoA ligase activity; IEA:InterPro.
DR GO; GO:0016208; F:AMP binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0019427; P:acetyl-CoA biosynthetic process from acetate; IEA:InterPro.
DR CDD; cd05966; ACS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR011904; Ac_CoA_lig.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR02188; Ac_CoA_lig_AcsA; 1.
DR PANTHER; PTHR24095; ACETYL-COENZYME A SYNTHETASE; 1.
DR PANTHER; PTHR24095:SF14; ACETYL-COENZYME A SYNTHETASE 1; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000001176}.
FT DOMAIN 25..80
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 83..467
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 529..605
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 645 AA; 69542 MW; 446E38D14AAABCCD CRC64;
MIHAETFPVP PSFAAQAAVD APRLRQMTDA ASQHPDQFWL DQAGRIDWAV RPTTASSSTF
GGDVAIRWFA DGTLNASANC LDRHLVTRGD QVALIWQGQD QGQVERLTYR ALHQRVCRMA
NVLRGLGVGR GDRVAIHLPM VIEGVVAMLA CARIGAVHVV LFGGFSAEGL ADRLVNSGAV
VVITADEGRR GAKRIPLKAT MDDAVARDGV QVRHVLVLAV TGAAVPMHAG RDLPLNPLLA
QAAEDCPAEI MGAEDPLFVL YTSGSTGKPK GMVHTTGGYM VWASYTHELV FDHRAGDVFW
CTADISWITG HTYVVYGPLA NGSTVVLFEG LPSHPAPGRW WEVIDTHKVT TFYTAPTAIR
ALMRDGDDVV DRYALDSLRL LGSVGEPISA DAWLWFHEKV GRGRCPVVDT WWQTETGGIL
IAPVPGAVPQ KPGAATLPLP GVACVLLTDK GAVIEGEGEG CLCVARSWPG QARTIWADHA
RFRQTYFTFS PGYYFSGDGA RRDADGYYWI TGRIDDVINV SGHRIGTAEI EDVVATDHRF
VECAAVGIPH DLKGQGLVVF AVARDMAEPG LAEAAALAVT RGVGRYAVPE RVYLVPDLPK
TRSGKIVRRL LRKIACHELD GLGDLSTLAD PTIVDRLIAE VARVA
//
