ID A9HXV9_BORPD Unreviewed; 450 AA.
AC A9HXV9;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Probable sodium/alanine symporter {ECO:0000313|EMBL:CAP40604.1};
GN OrderedLocusNames=Bpet0272 {ECO:0000313|EMBL:CAP40604.1};
OS Bordetella petrii (strain ATCC BAA-461 / DSM 12804 / CCUG 43448).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae; Bordetella.
OX NCBI_TaxID=340100 {ECO:0000313|EMBL:CAP40604.1, ECO:0000313|Proteomes:UP000001225};
RN [1] {ECO:0000313|EMBL:CAP40604.1, ECO:0000313|Proteomes:UP000001225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-461 / DSM 12804 / CCUG 43448
RC {ECO:0000313|Proteomes:UP000001225};
RX PubMed=18826580; DOI=10.1186/1471-2164-9-449;
RA Gross R., Guzman C.A., Sebaihia M., Martins Dos Santos V.A., Pieper D.H.,
RA Koebnik R., Lechner M., Bartels D., Buhrmester J., Choudhuri J.V.,
RA Ebensen T., Gaigalat L., Herrmann S., Khachane A.N., Larisch C., Link S.,
RA Linke B., Meyer F., Mormann S., Nakunst D., Rueckert C.,
RA Schneiker-Bekel S., Schulze K., Vorhoelter F.J., Yevsa T., Engle J.T.,
RA Goldman W.E., Puehler A., Goebel U.B., Goesmann A., Bloecker H., Kaiser O.,
RA Martinez-Arias R.;
RT "The missing link: Bordetella petrii is endowed with both the metabolic
RT versatility of environmental bacteria and virulence traits of pathogenic
RT Bordetellae.";
RL BMC Genomics 9:449-449(2008).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|RuleBase:RU363064}; Multi-pass membrane protein
CC {ECO:0000256|RuleBase:RU363064}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the alanine or glycine:cation symporter (AGCS)
CC (TC 2.A.25) family. {ECO:0000256|ARBA:ARBA00009261,
CC ECO:0000256|RuleBase:RU363064}.
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DR EMBL; AM902716; CAP40604.1; -; Genomic_DNA.
DR AlphaFoldDB; A9HXV9; -.
DR STRING; 94624.Bpet0272; -.
DR KEGG; bpt:Bpet0272; -.
DR eggNOG; COG1115; Bacteria.
DR Proteomes; UP000001225; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005283; F:amino acid:sodium symporter activity; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR001463; Na/Ala_symport.
DR NCBIfam; TIGR00835; agcS; 1.
DR PANTHER; PTHR30330; AGSS FAMILY TRANSPORTER, SODIUM-ALANINE; 1.
DR PANTHER; PTHR30330:SF3; TRANSCRIPTIONAL REGULATOR, LRP FAMILY-RELATED; 1.
DR Pfam; PF01235; Na_Ala_symp; 1.
DR PRINTS; PR00175; NAALASMPORT.
DR PROSITE; PS00873; NA_ALANINE_SYMP; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|RuleBase:RU363064};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363064};
KW Symport {ECO:0000256|RuleBase:RU363064};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU363064};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363064};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363064}.
FT TRANSMEM 20..45
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 66..93
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 147..167
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 187..205
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 214..235
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 241..268
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 310..331
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 351..373
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 393..413
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 419..437
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
SQ SEQUENCE 450 AA; 47282 MW; FA7AB2912A0898E3 CRC64;
MQFLDTLVNS LNGLVWGPPM LVLILGTGLF LMLRLGFMPL TKIAAGFRLA WRSRTRKDDD
SGEISPFQAL MTSLAATVGT GNIAGVATAI FLGGPGALFW MWVTALVGMA TKYSEVLLAV
HYREKDPRGE FTGGPMYAIR NGLGPKWAWL GVLFALFGGL AGFGIGNMVQ VNSMSDALQA
SFGVPDWVTG VVTMVLIGLV VLGGIRRIGA VAEALVPFMC IAYIVASVAA LVLMADAIPA
AFQLIFTHAF SPVAATGGFA GAAVMAAMRY GVARGIFSNE AGLGTAGIVQ AAGASKSAVR
SGMIGMIGTF IDTIIICTMT GLVIVCSGLW TSGDSGAVLS SSAYEAALPG IGNYVIAIAL
AIFAFTTILG WSYLSERCWE FLVGVRAILP FRIVWVIAVP FGAIAQLDFA WLLADTLNGL
MAVPNLIALV MLSPVVVKLT REHFARHPSE
//
