ID A9IQW0_BORPD Unreviewed; 843 AA.
AC A9IQW0;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=DNA internalization-related competence protein ComEC/Rec2 {ECO:0000313|EMBL:CAP43103.1};
GN OrderedLocusNames=Bpet2761 {ECO:0000313|EMBL:CAP43103.1};
OS Bordetella petrii (strain ATCC BAA-461 / DSM 12804 / CCUG 43448).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae; Bordetella.
OX NCBI_TaxID=340100 {ECO:0000313|EMBL:CAP43103.1, ECO:0000313|Proteomes:UP000001225};
RN [1] {ECO:0000313|EMBL:CAP43103.1, ECO:0000313|Proteomes:UP000001225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-461 / DSM 12804 / CCUG 43448
RC {ECO:0000313|Proteomes:UP000001225};
RX PubMed=18826580; DOI=10.1186/1471-2164-9-449;
RA Gross R., Guzman C.A., Sebaihia M., Martins Dos Santos V.A., Pieper D.H.,
RA Koebnik R., Lechner M., Bartels D., Buhrmester J., Choudhuri J.V.,
RA Ebensen T., Gaigalat L., Herrmann S., Khachane A.N., Larisch C., Link S.,
RA Linke B., Meyer F., Mormann S., Nakunst D., Rueckert C.,
RA Schneiker-Bekel S., Schulze K., Vorhoelter F.J., Yevsa T., Engle J.T.,
RA Goldman W.E., Puehler A., Goebel U.B., Goesmann A., Bloecker H., Kaiser O.,
RA Martinez-Arias R.;
RT "The missing link: Bordetella petrii is endowed with both the metabolic
RT versatility of environmental bacteria and virulence traits of pathogenic
RT Bordetellae.";
RL BMC Genomics 9:449-449(2008).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AM902716; CAP43103.1; -; Genomic_DNA.
DR AlphaFoldDB; A9IQW0; -.
DR STRING; 94624.Bpet2761; -.
DR KEGG; bpt:Bpet2761; -.
DR eggNOG; COG0658; Bacteria.
DR eggNOG; COG2333; Bacteria.
DR Proteomes; UP000001225; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0030420; P:establishment of competence for transformation; IEA:InterPro.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR004797; Competence_ComEC/Rec2.
DR InterPro; IPR025405; DUF4131.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR NCBIfam; TIGR00361; ComEC_Rec2; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF13567; DUF4131; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 27..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 61..77
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 284..305
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 325..346
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 352..368
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 427..450
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 462..485
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 497..519
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 525..542
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 582..778
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 843 AA; 89562 MW; 076B758A72ECC28E CRC64;
MVVGLRAQRT DICIHTRRPR PGPGLRCSFW ETGIVGRLFL LGLVAGTAAA QHLPALPGAD
WLLPWAAALL PAGAVACHRS RRGLARSVAT AWLGIGLGLA WAIWQGQLRL DDALADIHHD
QVSRLAVRVA DLPQGDAGRW RFVAEAGSDR PAGVPARIAV SWHAPPGVRL PELLPGQVWR
MALVLRRPYG ARNPQGYDAE ARLFALGIRA TATVRGMPVL LRDEPWSGAG IIIERIRHHV
REGMRHALGP RRHAPVLIAL AMGDQAGVAR EDWQIFNRSG ITHLVSISGM HVTLIAGLGG
VLAAFVWRRA RWGGIGLPER LPAQVVGAAA ALLVALLYCL LAGWGVPARR TFFMLAVVAL
AAMARLPLSP ARILALAAAA VVLFDPWATL APGFWLSFGA VAVLLRAAAS AAPALRRAGW
RDRVAALLGE FGRVQMAVTL GLVPLLAHLM HQVSLGSPLA NAFAIPIVSF IVTPLALLCA
AFGAVPGLGM LARACGVLGH AVFDWTMVPV SWIGSAHWAA VDVAAAPWPL LALAVAGVAW
ALQPPGWPAR GAGWLLMLPM LCWRPERPPP GHWTLTALDV GQGSAVLIET ASQAWLFDTG
PRYGDGADAA ARVVAPYLRA RGYRHLDGLV VSHADLDHAG GLASLLAALP VRQAYASFDL
AAFLREQAEA GAKAARARLP LSVQQCRAGQ AWQADGVTFR FLHPARAAPA RRGDGNAQSC
VLLVQGVVHA ALLPGDIGVA QERELAPALP RVHVVMAPHH GSATSSGAAL VEAAAAAHVI
AQAGRLNRFR HPAPQVQARW RRAGAMFWRT DWHGAITVEA RPEGVAAKAE ARAARRYWHR
AGP
//
