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Database: UniProt
Entry: A9KIL0_LACP7
LinkDB: A9KIL0_LACP7
Original site: A9KIL0_LACP7 
ID   A9KIL0_LACP7            Unreviewed;       697 AA.
AC   A9KIL0;
DT   05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   05-FEB-2008, sequence version 1.
DT   08-MAY-2019, entry version 71.
DE   RecName: Full=Ferrous iron transport protein B {ECO:0000256|RuleBase:RU362098};
GN   OrderedLocusNames=Cphy_3524 {ECO:0000313|EMBL:ABX43873.1};
OS   Lachnoclostridium phytofermentans (strain ATCC 700394 / DSM 18823 /
OS   ISDg) (Clostridium phytofermentans).
OC   Bacteria; Firmicutes; Clostridia; Clostridiales; Lachnospiraceae.
OX   NCBI_TaxID=357809 {ECO:0000313|EMBL:ABX43873.1, ECO:0000313|Proteomes:UP000000370};
RN   [1] {ECO:0000313|Proteomes:UP000000370}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700394 / DSM 18823 / ISDg
RC   {ECO:0000313|Proteomes:UP000000370};
RA   Leschine S.B., Warnick T.A., Blanchard J.L., Schnell D.J., Petit E.L.,
RA   LaTouf W.G., Copeland A., Lucas S., Lapidus A., Barry K.,
RA   Glavina del Rio T., Dalin E., Tice H., Pitluck S., Kiss H.,
RA   Brettin T., Bruce D., Detter J.C., Han C., Kuske C., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Kim E.A., Richardson P.;
RT   "Complete genome sequence of Clostridium phytofermentans ISDg.";
RL   Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable transporter of a GTP-driven Fe(2+) uptake
CC       system. {ECO:0000256|RuleBase:RU362098}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-
CC       like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
CC       {ECO:0000256|RuleBase:RU362098}.
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DR   EMBL; CP000885; ABX43873.1; -; Genomic_DNA.
DR   STRING; 357809.Cphy_3524; -.
DR   EnsemblBacteria; ABX43873; ABX43873; Cphy_3524.
DR   KEGG; cpy:Cphy_3524; -.
DR   eggNOG; ENOG4105CE1; Bacteria.
DR   eggNOG; COG0370; LUCA.
DR   HOGENOM; HOG000054021; -.
DR   KO; K04759; -.
DR   OMA; PLGYDWK; -.
DR   BioCyc; CPHY357809:G1GAJ-3667-MONOMER; -.
DR   Proteomes; UP000000370; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015093; F:ferrous iron transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   CDD; cd01879; FeoB; 1.
DR   InterPro; IPR003373; Fe2_transport_prot-B.
DR   InterPro; IPR011640; Fe2_transport_prot_B_C.
DR   InterPro; IPR041069; FeoB_Cyto.
DR   InterPro; IPR030389; G_FEOB_dom.
DR   InterPro; IPR011642; Gate_dom.
DR   InterPro; IPR006073; GTP_binding_domain.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   Pfam; PF07664; FeoB_C; 1.
DR   Pfam; PF17910; FeoB_Cyto; 1.
DR   Pfam; PF02421; FeoB_N; 1.
DR   Pfam; PF07670; Gate; 2.
DR   PRINTS; PR00326; GTP1OBG.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00437; feoB; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
DR   PROSITE; PS51711; G_FEOB; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000000370};
KW   GTP-binding {ECO:0000256|RuleBase:RU362098};
KW   Ion transport {ECO:0000256|RuleBase:RU362098};
KW   Iron {ECO:0000256|RuleBase:RU362098};
KW   Iron transport {ECO:0000256|RuleBase:RU362098};
KW   Membrane {ECO:0000256|RuleBase:RU362098};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU362098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000370};
KW   Transmembrane {ECO:0000256|RuleBase:RU362098};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU362098};
KW   Transport {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    305    325       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    360    389       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    409    433       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    445    464       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    470    495       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    533    554       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    574    595       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    639    659       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    671    694       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   DOMAIN       15    177       FeoB-type G. {ECO:0000259|PROSITE:
FT                                PS51711}.
SQ   SEQUENCE   697 AA;  78117 MW;  FF9A7037DF55EB68 CRC64;
     MLTMIQEENL REEQELKVGF VGNPNCGKTT LFNAYTGAKL KVANWPGVTV EKKEGAMKYH
     DHRFKLVDLP GIYSLTSYTM EEKLTRQFIL DSEVEVIIDV ADASALERNL YLTLQLIELG
     KPVILALNMM DIVEERGMEI DMHRLPEMLG IPCIPVSARR RTGLDILMHT VAHHKEKCRH
     NSIVHQHPNL GKSKSHHAHE HHKEFTMVYS DEIEDKIDIL TDRMKEVGFE SENYRWYALK
     LLEHDEEVMN LVSIDLAGIA NESYEAEIIH QKYDFIDEII EECLVNKSKK AALTDKVDRV
     VTHRIFGLPV FLGIMAVVFF LTFTIGDFLK GYFEVGLESF STMALKGLEA IGTNEMLTSL
     IVNGIIAGVG GILTFLPNIF ILFLALAFLE DSGYMARVAY VMDGLMGKLG LSGRAFIPMI
     LGFGCTVPAV MASRALEDMR DRRRTVLITP FMSCSARLPI YVLFSQMFFG RYAMLVAFSM
     YVVGLVIAVI SAFVMNKFGK KGNMSPLLIE LPEYKTPNKR TIFIYVWDKV KDYLTKAGTT
     IFLASIVIWF ILNFGPQGMT EDMSQSFGAI FGKFASPILV PAGLGLWQIV VALISGLAAK
     EVVVSSFSVL YGIANISSRE GMNTLISSLS SQNFTAVNAY SFMLFCLLYT PCVATIAVVK
     RELKSTKWTI FSILFQLGVA YLVSVLFFQI GSFITSL
//
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