ID A9KLL2_LACP7 Unreviewed; 390 AA.
AC A9KLL2;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE RecName: Full=ribose-phosphate diphosphokinase {ECO:0000256|ARBA:ARBA00013247};
DE EC=2.7.6.1 {ECO:0000256|ARBA:ARBA00013247};
GN OrderedLocusNames=Cphy_2395 {ECO:0000313|EMBL:ABX42756.1};
OS Lachnoclostridium phytofermentans (strain ATCC 700394 / DSM 18823 / ISDg)
OS (Clostridium phytofermentans).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=357809 {ECO:0000313|EMBL:ABX42756.1, ECO:0000313|Proteomes:UP000000370};
RN [1] {ECO:0000313|Proteomes:UP000000370}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700394 / DSM 18823 / ISDg
RC {ECO:0000313|Proteomes:UP000000370};
RA Leschine S.B., Warnick T.A., Blanchard J.L., Schnell D.J., Petit E.L.,
RA LaTouf W.G., Copeland A., Lucas S., Lapidus A., Barry K.,
RA Glavina del Rio T., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T.,
RA Bruce D., Detter J.C., Han C., Kuske C., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Kim E.A., Richardson P.;
RT "Complete genome sequence of Clostridium phytofermentans ISDg.";
RL Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ribose-phosphate pyrophosphokinase family.
CC {ECO:0000256|RuleBase:RU004324}.
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DR EMBL; CP000885; ABX42756.1; -; Genomic_DNA.
DR AlphaFoldDB; A9KLL2; -.
DR STRING; 357809.Cphy_2395; -.
DR KEGG; cpy:Cphy_2395; -.
DR eggNOG; COG0462; Bacteria.
DR HOGENOM; CLU_033546_8_0_9; -.
DR Proteomes; UP000000370; Chromosome.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:InterPro.
DR GO; GO:0009165; P:nucleotide biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd06223; PRTases_typeI; 1.
DR Gene3D; 3.40.50.2020; -; 2.
DR InterPro; IPR029099; Pribosyltran_N.
DR InterPro; IPR000836; PRibTrfase_dom.
DR InterPro; IPR029057; PRTase-like.
DR InterPro; IPR005946; Rib-P_diPkinase.
DR NCBIfam; TIGR01251; ribP_PPkin; 1.
DR PANTHER; PTHR10210:SF32; RIBOSE-PHOSPHATE DIPHOSPHOKINASE; 1.
DR PANTHER; PTHR10210; RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER; 1.
DR Pfam; PF00156; Pribosyltran; 1.
DR Pfam; PF13793; Pribosyltran_N; 1.
DR SUPFAM; SSF53271; PRTase-like; 2.
PE 3: Inferred from homology;
KW Kinase {ECO:0000313|EMBL:ABX42756.1};
KW Nucleotide biosynthesis {ECO:0000256|ARBA:ARBA00022727,
KW ECO:0000256|RuleBase:RU004324};
KW Reference proteome {ECO:0000313|Proteomes:UP000000370};
KW Transferase {ECO:0000313|EMBL:ABX42756.1}.
FT DOMAIN 15..166
FT /note="Ribose-phosphate pyrophosphokinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13793"
FT DOMAIN 199..308
FT /note="Phosphoribosyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00156"
SQ SEQUENCE 390 AA; 44483 MW; 67D1F11131716070 CRC64;
MSNRKITETI PVAPLKIIAM KNCTSLGTKI DQCIVEARRA MLENNEALPA FLGYDNSTYL
VSYEVPRFGT GEAKAVINET IRGCDLFLIA DVTNYTNHYM MFGEDSMKSP DDHFQDLKRV
IAAAKISKVK RVNVILPFLY EGRQHHRDKL ESLDCANALQ ELSEMGVENI ITFDAHDPRI
QNAIPIRGFD NFYTSLQFIR ELLFIEKDLV IDKDHLMVIS PDEGGMTRAV YYANVLGVEM
GMFYKRRDYS TIIDGRNPIV AHEFLGSSLE GKDVFIVDDI ISSGDSIIDV AKELKRRKAG
RVFIAATFGL FCNGLERVDE YYEAGYIDRI YTTNLVYNNE ELLKRPYYRN VDLSRYISLI
VDTLNHDTSV NDIINPAALI QELLKSYRMK
//
