ID A9KT97_LACP7 Unreviewed; 702 AA.
AC A9KT97;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE RecName: Full=Glutamine synthetase {ECO:0000256|ARBA:ARBA00021364};
GN OrderedLocusNames=Cphy_3374 {ECO:0000313|EMBL:ABX43727.1};
OS Lachnoclostridium phytofermentans (strain ATCC 700394 / DSM 18823 / ISDg)
OS (Clostridium phytofermentans).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=357809 {ECO:0000313|EMBL:ABX43727.1, ECO:0000313|Proteomes:UP000000370};
RN [1] {ECO:0000313|Proteomes:UP000000370}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700394 / DSM 18823 / ISDg
RC {ECO:0000313|Proteomes:UP000000370};
RA Leschine S.B., Warnick T.A., Blanchard J.L., Schnell D.J., Petit E.L.,
RA LaTouf W.G., Copeland A., Lucas S., Lapidus A., Barry K.,
RA Glavina del Rio T., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T.,
RA Bruce D., Detter J.C., Han C., Kuske C., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Kim E.A., Richardson P.;
RT "Complete genome sequence of Clostridium phytofermentans ISDg.";
RL Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glutamine synthetase family.
CC {ECO:0000256|PROSITE-ProRule:PRU01330, ECO:0000256|RuleBase:RU000384}.
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DR EMBL; CP000885; ABX43727.1; -; Genomic_DNA.
DR RefSeq; WP_012201376.1; NC_010001.1.
DR AlphaFoldDB; A9KT97; -.
DR STRING; 357809.Cphy_3374; -.
DR KEGG; cpy:Cphy_3374; -.
DR eggNOG; COG3968; Bacteria.
DR HOGENOM; CLU_024307_0_0_9; -.
DR OrthoDB; 9807095at2; -.
DR Proteomes; UP000000370; Chromosome.
DR GO; GO:0004356; F:glutamine synthetase activity; IEA:InterPro.
DR GO; GO:0006542; P:glutamine biosynthetic process; IEA:InterPro.
DR Gene3D; 1.20.120.1560; -; 1.
DR Gene3D; 3.30.590.10; Glutamine synthetase/guanido kinase, catalytic domain; 1.
DR InterPro; IPR040577; Gln-synt_C.
DR InterPro; IPR008147; Gln_synt_N.
DR InterPro; IPR014746; Gln_synth/guanido_kin_cat_dom.
DR InterPro; IPR008146; Gln_synth_cat_dom.
DR InterPro; IPR027303; Gln_synth_gly_rich_site.
DR InterPro; IPR022147; GSIII_N.
DR PANTHER; PTHR42974; GLUTAMINE SYNTHETASE; 1.
DR PANTHER; PTHR42974:SF1; TYPE-3 GLUTAMINE SYNTHETASE; 1.
DR Pfam; PF00120; Gln-synt_C; 1.
DR Pfam; PF18318; Gln-synt_C-ter; 1.
DR Pfam; PF12437; GSIII_N; 1.
DR SMART; SM01230; Gln-synt_C; 1.
DR SUPFAM; SSF55931; Glutamine synthetase/guanido kinase; 1.
DR PROSITE; PS00181; GLNA_ATP; 1.
DR PROSITE; PS51986; GS_BETA_GRASP; 1.
DR PROSITE; PS51987; GS_CATALYTIC; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000370}.
FT DOMAIN 63..156
FT /note="GS beta-grasp"
FT /evidence="ECO:0000259|PROSITE:PS51986"
FT DOMAIN 161..592
FT /note="GS catalytic"
FT /evidence="ECO:0000259|PROSITE:PS51987"
SQ SEQUENCE 702 AA; 77270 MW; DDBA341AC35925D2 CRC64;
MAEKLTDIFG IDVFDEATMM ECLPKRTFEA LKKTIKNGED LDPQVAEIVA NAMKDWAIDR
GATHYTHWFQ PMTGITAEKH DSFISPAPSG KILMEFSGKE LIKGEPDASS FPSGGLRATF
EARGYTAWDC TSPAFLKEDA AGVTLCIPTA FCAYTGEALD KKTPLLRSME AISKHAVRIC
KLFGHSDVTS VSCSVGAEQE YFLVDRENYL KRDDLLFTGR TLFGAMPPKG QELDDHYFGS
IRERIASFMK ELNVELWKLG ILAKTQHNEA APAQHEIAPI YTTANIATDH NQLIMDIMKK
VAIRHGLACL LHEKPFAGVN GSGKHDNWSI VTNTGKNLLE PGKTPHENVQ FLLFLSAILK
AVDLHADLLR LSASNPGNDH RLGANEAPPA IISVFLGEQL ADVLTQLIET GAATSSKQGG
RLRTGVHTLP ELKKDATDRN RTSPFAFTGN KFEFRMVGSS MSIADANTTV NTIVADVLSD
MADELEKADD FDLAVHDLIK KTVTKHQRIV FNGNGYSDAW VEEAERRGLP NLNSMVAAVP
ALVTEKAIKL FDKHHVLTTT ELKSRVEVLY ESYSKAINIE AKTMIEMANR MFIPAVIKFT
TTLANSINAV KTAVPTADVS VQADLLTETS TLLAQAKAAL NNLSKYTKTA ASIEEGEEQA
NYFRNVVFPA MDELRTPIDL LETIVDKEVW PVPTYGDLLF EV
//
