ID ACTP_SALAR Reviewed; 549 AA.
AC A9MGK8;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 84.
DE RecName: Full=Cation/acetate symporter ActP {ECO:0000255|HAMAP-Rule:MF_01426};
DE AltName: Full=Acetate permease {ECO:0000255|HAMAP-Rule:MF_01426};
DE AltName: Full=Acetate transporter ActP {ECO:0000255|HAMAP-Rule:MF_01426};
GN Name=actP {ECO:0000255|HAMAP-Rule:MF_01426}; OrderedLocusNames=SARI_03402;
OS Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=41514;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-731 / CDC346-86 / RSK2980;
RG The Salmonella enterica serovar Arizonae Genome Sequencing Project;
RA McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S.,
RA Fulton R., Chunyan W., Wollam A., Shah N., Pepin K., Bhonagiri V., Nash W.,
RA Johnson M., Thiruvilangam P., Wilson R.;
RL Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Transports acetate. {ECO:0000255|HAMAP-Rule:MF_01426}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01426}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01426}.
CC -!- SIMILARITY: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21)
CC family. {ECO:0000255|HAMAP-Rule:MF_01426}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000880; ABX23232.1; -; Genomic_DNA.
DR AlphaFoldDB; A9MGK8; -.
DR SMR; A9MGK8; -.
DR STRING; 41514.SARI_03402; -.
DR KEGG; ses:SARI_03402; -.
DR HOGENOM; CLU_018808_8_3_6; -.
DR Proteomes; UP000002084; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015123; F:acetate transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0043879; F:glycolate transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR CDD; cd11480; SLC5sbd_u4; 1.
DR Gene3D; 1.20.1730.10; Sodium/glucose cotransporter; 1.
DR HAMAP; MF_01426; Acet_symport_ActP; 1.
DR InterPro; IPR014083; Cation/Ac_symporter_ActP.
DR InterPro; IPR038377; Na/Glc_symporter_sf.
DR InterPro; IPR001734; Na/solute_symporter.
DR InterPro; IPR018212; Na/solute_symporter_CS.
DR NCBIfam; TIGR00813; sss; 1.
DR NCBIfam; TIGR02711; symport_actP; 1.
DR PANTHER; PTHR48086:SF6; CATION_ACETATE SYMPORTER ACTP; 1.
DR PANTHER; PTHR48086; SODIUM/PROLINE SYMPORTER-RELATED; 1.
DR Pfam; PF00474; SSF; 1.
DR PROSITE; PS00456; NA_SOLUT_SYMP_1; 1.
DR PROSITE; PS00457; NA_SOLUT_SYMP_2; 1.
DR PROSITE; PS50283; NA_SOLUT_SYMP_3; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Ion transport; Membrane;
KW Reference proteome; Sodium; Sodium transport; Symport; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..549
FT /note="Cation/acetate symporter ActP"
FT /id="PRO_1000087425"
FT TRANSMEM 33..53
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT TRANSMEM 77..97
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT TRANSMEM 103..123
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT TRANSMEM 148..168
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT TRANSMEM 183..203
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT TRANSMEM 206..226
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT TRANSMEM 262..282
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT TRANSMEM 303..323
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT TRANSMEM 355..375
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT TRANSMEM 404..424
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT TRANSMEM 428..448
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT TRANSMEM 464..484
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT TRANSMEM 493..513
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
SQ SEQUENCE 549 AA; 59009 MW; 1D7B6860AB66F3F0 CRC64;
MKRVLTALAA ALPFAAHAAD AISGAVERQP TNWQAIIMFL IFVVFTLGIT YWASKRVRSR
SDYYTAGGNI TGFQNGLAIA GDYMSAASFL GISALVFTSG YDGLIYSLGF LVGWPIILFL
IAERLRNLGR YTFADVASYR LKQGPIRILS ACGSLVVVAL YLIAQMVGAG KLIELLFGLN
YHIAVVLVGV LMMMYVLFGG MLATTWVQII KAVLLLFGAS FMAFMVMKHV GFSFNNLFTE
AMAVHPKGTA IMSPGGLVQD PISALSLGLG LMFGTAGLPH ILMRFFTVSD AREARKSVFY
ATGFMGYFYI LTFIIGFGAI MLVGANPAYK DAAGALIGGN NMAAVHLANA VGGNLFLGFI
SAVAFATILA VVAGLTLAGA SAVSHDLYAN VFRKGATERE ELKVSKITVL VLGVIAIILG
VLFENQNIAF MVGLAFAIAA SCNFPIILLS MYWSKLTTRG AMLGGWLGLL TAVVLMILGP
TIWVQILGHE KAIFPYEYPA LFSISVAFLG IWFFSATDNS AEGNREREQF RAQFIRSQTG
FGVEQGRAH
//
