ID A9SGF0_PHYPA Unreviewed; 232 AA.
AC A9SGF0;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE RecName: Full=Iron transporter {ECO:0008006|Google:ProtNLM};
GN ORFNames=PHYPA_003632 {ECO:0000313|EMBL:PNR60839.1};
OS Physcomitrium patens (Spreading-leaved earth moss) (Physcomitrella patens).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Bryophyta;
OC Bryophytina; Bryopsida; Funariidae; Funariales; Funariaceae; Physcomitrium.
OX NCBI_TaxID=3218 {ECO:0000313|EMBL:PNR60839.1};
RN [1] {ECO:0000313|EMBL:PNR60839.1, ECO:0000313|Proteomes:UP000006727}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Gransden 2004 {ECO:0000313|EnsemblPlants:Pp3c2_34540V3.1,
RC ECO:0000313|Proteomes:UP000006727};
RX PubMed=18079367; DOI=10.1126/science.1150646;
RA Rensing S.A., Lang D., Zimmer A.D., Terry A., Salamov A., Shapiro H.,
RA Nishiyama T., Perroud P.-F., Lindquist E.A., Kamisugi Y., Tanahashi T.,
RA Sakakibara K., Fujita T., Oishi K., Shin-I T., Kuroki Y., Toyoda A.,
RA Suzuki Y., Hashimoto S.-I., Yamaguchi K., Sugano S., Kohara Y.,
RA Fujiyama A., Anterola A., Aoki S., Ashton N., Barbazuk W.B., Barker E.,
RA Bennetzen J.L., Blankenship R., Cho S.H., Dutcher S.K., Estelle M.,
RA Fawcett J.A., Gundlach H., Hanada K., Heyl A., Hicks K.A., Hughes J.,
RA Lohr M., Mayer K., Melkozernov A., Murata T., Nelson D.R., Pils B.,
RA Prigge M., Reiss B., Renner T., Rombauts S., Rushton P.J., Sanderfoot A.,
RA Schween G., Shiu S.-H., Stueber K., Theodoulou F.L., Tu H., Van de Peer Y.,
RA Verrier P.J., Waters E., Wood A., Yang L., Cove D., Cuming A.C., Hasebe M.,
RA Lucas S., Mishler B.D., Reski R., Grigoriev I.V., Quatrano R.S.,
RA Boore J.L.;
RT "The Physcomitrella genome reveals evolutionary insights into the conquest
RT of land by plants.";
RL Science 319:64-69(2008).
RN [2] {ECO:0000313|EMBL:PNR60839.1, ECO:0000313|Proteomes:UP000006727}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Gransden 2004 {ECO:0000313|EnsemblPlants:Pp3c2_34540V3.1,
RC ECO:0000313|Proteomes:UP000006727};
RX PubMed=29237241; DOI=10.1111/tpj.13801;
RA Lang D., Ullrich K.K., Murat F., Fuchs J., Jenkins J., Haas F.B.,
RA Piednoel M., Gundlach H., Van Bel M., Meyberg R., Vives C., Morata J.,
RA Symeonidi A., Hiss M., Muchero W., Kamisugi Y., Saleh O., Blanc G.,
RA Decker E.L., van Gessel N., Grimwood J., Hayes R.D., Graham S.W.,
RA Gunter L.E., McDaniel S.F., Hoernstein S.N.W., Larsson A., Li F.W.,
RA Perroud P.F., Phillips J., Ranjan P., Rokshar D.S., Rothfels C.J.,
RA Schneider L., Shu S., Stevenson D.W., Thummler F., Tillich M.,
RA Villarreal Aguilar J.C., Widiez T., Wong G.K., Wymore A., Zhang Y.,
RA Zimmer A.D., Quatrano R.S., Mayer K.F.X., Goodstein D., Casacuberta J.M.,
RA Vandepoele K., Reski R., Cuming A.C., Tuskan G.A., Maumus F., Salse J.,
RA Schmutz J., Rensing S.A.;
RT "The Physcomitrella patens chromosome-scale assembly reveals moss genome
RT structure and evolution.";
RL Plant J. 93:515-533(2018).
RN [3] {ECO:0000313|EnsemblPlants:Pp3c2_34540V3.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (DEC-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CCC1 family.
CC {ECO:0000256|ARBA:ARBA00007049}.
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DR EMBL; ABEU02000002; PNR60839.1; -; Genomic_DNA.
DR RefSeq; XP_001765423.1; XM_001765371.1.
DR AlphaFoldDB; A9SGF0; -.
DR STRING; 3218.A9SGF0; -.
DR PaxDb; 3218-PP1S76_45V6-1; -.
DR EnsemblPlants; Pp3c2_34540V3.1; Pp3c2_34540V3.1; Pp3c2_34540.
DR EnsemblPlants; Pp3c2_34540V3.2; Pp3c2_34540V3.2; Pp3c2_34540.
DR EnsemblPlants; Pp3c2_34540V3.3; Pp3c2_34540V3.3; Pp3c2_34540.
DR EnsemblPlants; Pp3c2_34540V3.4; Pp3c2_34540V3.4; Pp3c2_34540.
DR EnsemblPlants; Pp3c2_34540V3.5; Pp3c2_34540V3.5; Pp3c2_34540.
DR EnsemblPlants; Pp3c2_34540V3.6; Pp3c2_34540V3.6; Pp3c2_34540.
DR Gramene; Pp3c2_34540V3.1; Pp3c2_34540V3.1; Pp3c2_34540.
DR Gramene; Pp3c2_34540V3.2; Pp3c2_34540V3.2; Pp3c2_34540.
DR Gramene; Pp3c2_34540V3.3; Pp3c2_34540V3.3; Pp3c2_34540.
DR Gramene; Pp3c2_34540V3.4; Pp3c2_34540V3.4; Pp3c2_34540.
DR Gramene; Pp3c2_34540V3.5; Pp3c2_34540V3.5; Pp3c2_34540.
DR Gramene; Pp3c2_34540V3.6; Pp3c2_34540V3.6; Pp3c2_34540.
DR eggNOG; KOG4473; Eukaryota.
DR HOGENOM; CLU_038957_0_2_1; -.
DR InParanoid; A9SGF0; -.
DR OMA; MNFHHTL; -.
DR OrthoDB; 1357at2759; -.
DR Proteomes; UP000006727; Chromosome 2.
DR GO; GO:0005774; C:vacuolar membrane; IBA:GO_Central.
DR GO; GO:0005381; F:iron ion transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0005384; F:manganese ion transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0030026; P:intracellular manganese ion homeostasis; IBA:GO_Central.
DR GO; GO:0006880; P:intracellular sequestering of iron ion; IBA:GO_Central.
DR CDD; cd02435; CCC1; 1.
DR InterPro; IPR008217; Ccc1_fam.
DR PANTHER; PTHR31851; FE(2+)/MN(2+) TRANSPORTER PCL1; 1.
DR PANTHER; PTHR31851:SF52; PROTEIN CCC1; 1.
DR Pfam; PF01988; VIT1; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006727};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 151..172
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 178..196
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 208..230
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 232 AA; 24636 MW; 5AD78B6C2483C03F CRC64;
MPATNHMERH FTAGQIVHDI VIGMSDGLTV PFALAAGLSG ASASSSIVVT AGLAEVAAGS
IAMGLGGYLA ERSDADHYEN ERKREEAEIV EVPDTEADEV AEILASYGLE PNEYWPVVNA
LRKRPEAWVD FMMRFELGLE KPDPARALQS ALTIAGSYIV GGLIPLLPYI IIPQVAKALK
VSVLVTISAL FVFGYVKGQF TGLRPVWSAF QTVFIGALAS AAAFTIAKAI SA
//
