ID A9SWY7_PHYPA Unreviewed; 566 AA.
AC A9SWY7;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE RecName: Full=FAD-binding PCMH-type domain-containing protein {ECO:0000259|PROSITE:PS51387};
GN ORFNames=PHYPA_009717 {ECO:0000313|EMBL:PNR50531.1};
OS Physcomitrium patens (Spreading-leaved earth moss) (Physcomitrella patens).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Bryophyta;
OC Bryophytina; Bryopsida; Funariidae; Funariales; Funariaceae; Physcomitrium.
OX NCBI_TaxID=3218 {ECO:0000313|EMBL:PNR50531.1};
RN [1] {ECO:0000313|EMBL:PNR50531.1, ECO:0000313|Proteomes:UP000006727}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Gransden 2004 {ECO:0000313|EnsemblPlants:Pp3c7_650V3.1,
RC ECO:0000313|Proteomes:UP000006727};
RX PubMed=18079367; DOI=10.1126/science.1150646;
RA Rensing S.A., Lang D., Zimmer A.D., Terry A., Salamov A., Shapiro H.,
RA Nishiyama T., Perroud P.-F., Lindquist E.A., Kamisugi Y., Tanahashi T.,
RA Sakakibara K., Fujita T., Oishi K., Shin-I T., Kuroki Y., Toyoda A.,
RA Suzuki Y., Hashimoto S.-I., Yamaguchi K., Sugano S., Kohara Y.,
RA Fujiyama A., Anterola A., Aoki S., Ashton N., Barbazuk W.B., Barker E.,
RA Bennetzen J.L., Blankenship R., Cho S.H., Dutcher S.K., Estelle M.,
RA Fawcett J.A., Gundlach H., Hanada K., Heyl A., Hicks K.A., Hughes J.,
RA Lohr M., Mayer K., Melkozernov A., Murata T., Nelson D.R., Pils B.,
RA Prigge M., Reiss B., Renner T., Rombauts S., Rushton P.J., Sanderfoot A.,
RA Schween G., Shiu S.-H., Stueber K., Theodoulou F.L., Tu H., Van de Peer Y.,
RA Verrier P.J., Waters E., Wood A., Yang L., Cove D., Cuming A.C., Hasebe M.,
RA Lucas S., Mishler B.D., Reski R., Grigoriev I.V., Quatrano R.S.,
RA Boore J.L.;
RT "The Physcomitrella genome reveals evolutionary insights into the conquest
RT of land by plants.";
RL Science 319:64-69(2008).
RN [2] {ECO:0000313|EMBL:PNR50531.1, ECO:0000313|Proteomes:UP000006727}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Gransden 2004 {ECO:0000313|EnsemblPlants:Pp3c7_650V3.1,
RC ECO:0000313|Proteomes:UP000006727};
RX PubMed=29237241; DOI=10.1111/tpj.13801;
RA Lang D., Ullrich K.K., Murat F., Fuchs J., Jenkins J., Haas F.B.,
RA Piednoel M., Gundlach H., Van Bel M., Meyberg R., Vives C., Morata J.,
RA Symeonidi A., Hiss M., Muchero W., Kamisugi Y., Saleh O., Blanc G.,
RA Decker E.L., van Gessel N., Grimwood J., Hayes R.D., Graham S.W.,
RA Gunter L.E., McDaniel S.F., Hoernstein S.N.W., Larsson A., Li F.W.,
RA Perroud P.F., Phillips J., Ranjan P., Rokshar D.S., Rothfels C.J.,
RA Schneider L., Shu S., Stevenson D.W., Thummler F., Tillich M.,
RA Villarreal Aguilar J.C., Widiez T., Wong G.K., Wymore A., Zhang Y.,
RA Zimmer A.D., Quatrano R.S., Mayer K.F.X., Goodstein D., Casacuberta J.M.,
RA Vandepoele K., Reski R., Cuming A.C., Tuskan G.A., Maumus F., Salse J.,
RA Schmutz J., Rensing S.A.;
RT "The Physcomitrella patens chromosome-scale assembly reveals moss genome
RT structure and evolution.";
RL Plant J. 93:515-533(2018).
RN [3] {ECO:0000313|EnsemblPlants:Pp3c7_650V3.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (DEC-2020) to UniProtKB.
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DR EMBL; ABEU02000007; PNR50531.1; -; Genomic_DNA.
DR RefSeq; XP_001770811.1; XM_001770759.1.
DR AlphaFoldDB; A9SWY7; -.
DR STRING; 3218.A9SWY7; -.
DR PaxDb; 3218-PP1S130_191V6-1; -.
DR EnsemblPlants; Pp3c7_650V3.1; Pp3c7_650V3.1; Pp3c7_650.
DR EnsemblPlants; Pp3c7_650V3.2; Pp3c7_650V3.2; Pp3c7_650.
DR EnsemblPlants; Pp3c7_650V3.3; Pp3c7_650V3.3; Pp3c7_650.
DR EnsemblPlants; Pp3c7_650V3.4; Pp3c7_650V3.4; Pp3c7_650.
DR Gramene; Pp3c7_650V3.1; Pp3c7_650V3.1; Pp3c7_650.
DR Gramene; Pp3c7_650V3.2; Pp3c7_650V3.2; Pp3c7_650.
DR Gramene; Pp3c7_650V3.3; Pp3c7_650V3.3; Pp3c7_650.
DR Gramene; Pp3c7_650V3.4; Pp3c7_650V3.4; Pp3c7_650.
DR eggNOG; KOG1262; Eukaryota.
DR HOGENOM; CLU_025883_4_0_1; -.
DR InParanoid; A9SWY7; -.
DR OMA; WVGRSAF; -.
DR OrthoDB; 5486440at2759; -.
DR Proteomes; UP000006727; Chromosome 7.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0050614; F:delta24-sterol reductase activity; IEA:UniProtKB-EC.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IBA:GO_Central.
DR GO; GO:0008202; P:steroid metabolic process; IBA:GO_Central.
DR Gene3D; 3.30.465.10; -; 1.
DR InterPro; IPR040165; Diminuto-like.
DR InterPro; IPR016166; FAD-bd_PCMH.
DR InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR InterPro; IPR006094; Oxid_FAD_bind_N.
DR PANTHER; PTHR10801; 24-DEHYDROCHOLESTEROL REDUCTASE; 1.
DR PANTHER; PTHR10801:SF0; DELTA(24)-STEROL REDUCTASE; 1.
DR Pfam; PF01565; FAD_binding_4; 1.
DR SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR PROSITE; PS51387; FAD_PCMH; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006727}.
FT DOMAIN 52..231
FT /note="FAD-binding PCMH-type"
FT /evidence="ECO:0000259|PROSITE:PS51387"
SQ SEQUENCE 566 AA; 66211 MW; 53CC694C75CBBE15 CRC64;
MGDLQKPLRP KKRTTWVDWA VQFRWILVIL VVLPVSKSFD TVAWFREQWS AFKSEKRRQK
EHDENVEKVI KRLKSRDPSK DGLVCTARRP WIAVGMRNVD YKRARHFEVD LNDFNQVLEI
DRENMIARCE PLVNMGQITR MTVPMGLSLA VVAELDDLTV GGLINGYGIE GSSHIYGLFA
DTCVAYEIIL ADGRLVRATA DNEFSDLFYA IPWSQGTLGL LVAAEIKLIE VGPYMKVTYK
PARGDLQELA QAYNDSYIPR DGDQDNPEKV PDFVETMIYS ETEGVTMTGR YASKDEAKRK
GNKINCQGWW YKKWFYQHAQ EALTRGEFVE YIPTRDYYHR HTRCLYWEGK LILPFADQFW
FRYLFGWMMP PKVSFLKATQ GDAIRNYYHE RHVIQDMLVP SYKVGMALEF SDREFEVYPI
WLCPHRLFKH PMRTQINPEP GFEYAGRPGD TPYAQMYTDV GVYYTPRCVF KGEEFDGVAA
VKKMEAWMIE NHCFQPQYAV SELNERDFWR MFDPTLYQRC RDKYKAVGTF MSVYYKCKKG
RKTEKEVAEE EAKVTESAYA DVEKPE
//
