ID A9UNU3_MONBE Unreviewed; 411 AA.
AC A9UNU3;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=Mitochondrial cardiolipin hydrolase {ECO:0000256|ARBA:ARBA00040549};
DE Flags: Fragment;
GN ORFNames=MONBRDRAFT_1366 {ECO:0000313|EMBL:EDQ92303.1};
OS Monosiga brevicollis (Choanoflagellate).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Monosiga.
OX NCBI_TaxID=81824 {ECO:0000313|EMBL:EDQ92303.1, ECO:0000313|Proteomes:UP000001357};
RN [1] {ECO:0000313|EMBL:EDQ92303.1, ECO:0000313|Proteomes:UP000001357}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MX1 / ATCC 50154 {ECO:0000313|Proteomes:UP000001357};
RX PubMed=18273011; DOI=10.1038/nature06617;
RG JGI Sequencing;
RA King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J.,
RA Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D.,
RA Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M.,
RA Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S.,
RA Richter D.J., Salamov A., Bork P., Lim W.A., Manning G., Miller W.T.,
RA McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D.;
RT "The genome of the choanoflagellate Monosiga brevicollis and the origin of
RT metazoans.";
RL Nature 451:783-788(2008).
CC -!- SIMILARITY: Belongs to the phospholipase D family. MitoPLD/Zucchini
CC subfamily. {ECO:0000256|ARBA:ARBA00038012}.
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DR EMBL; CH991543; EDQ92303.1; -; Genomic_DNA.
DR RefSeq; XP_001742065.1; XM_001742013.1.
DR AlphaFoldDB; A9UNU3; -.
DR STRING; 81824.A9UNU3; -.
DR EnsemblProtists; EDQ92303; EDQ92303; MONBRDRAFT_1366.
DR GeneID; 5887902; -.
DR KEGG; mbr:MONBRDRAFT_1366; -.
DR eggNOG; ENOG502RYRD; Eukaryota.
DR InParanoid; A9UNU3; -.
DR OMA; MYTYSHQ; -.
DR Proteomes; UP000001357; Unassembled WGS sequence.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR GO; GO:0016891; F:RNA endonuclease activity, producing 5'-phosphomonoesters; IBA:GO_Central.
DR Gene3D; 3.30.870.10; Endonuclease Chain A; 2.
DR InterPro; IPR025202; PLD-like_dom.
DR InterPro; IPR001736; PLipase_D/transphosphatidylase.
DR PANTHER; PTHR43856; CARDIOLIPIN HYDROLASE; 1.
DR PANTHER; PTHR43856:SF1; MITOCHONDRIAL CARDIOLIPIN HYDROLASE; 1.
DR Pfam; PF13091; PLDc_2; 2.
DR SMART; SM00155; PLDc; 2.
DR SUPFAM; SSF56024; Phospholipase D/nuclease; 2.
DR PROSITE; PS50035; PLD; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001357}.
FT DOMAIN 131..158
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
FT DOMAIN 331..358
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EDQ92303.1"
FT NON_TER 411
FT /evidence="ECO:0000313|EMBL:EDQ92303.1"
SQ SEQUENCE 411 AA; 46039 MW; A6EEF3F8D1D48443 CRC64;
SYDHQSKTYV SSFKPLTLSG VDINVTPYFS PDHSAEMLVK IIDGAKKTLD IYTPGFSSWQ
GCSPYSGCGG CNVSVVAAEP FPVFPALLNA VHRGVAVRII TNDYNVHTCE GVITPLDYLK
LNGVDIRYYT STTFMHSKVL VRDGVEVSIG SVNWTKNSIL NDREAAMFFT GTNAAADLAK
YVLSVYEQDW AQTYNYTLDH TYSPQDMAII TNTSLQPVNV PQGPDRPYIT PEPSAISVNT
DVEIWTSPDY AYTTIMEDID SAETSFALYI YQVTDKRLCE KLINVTQAGL NLTLLVSYRI
YGTTDYELAK SCYETLYQNG VVIRSAYAFT YSFYNHQKFW IADGKRVTLA TGNWSPSDYP
GPPGSYPVFG QEGWQSVNRD FTVRVANKDV VDVFDKVLTM DYLNGTYWKP Y
//
