ID A9UNX0_MONBE Unreviewed; 589 AA.
AC A9UNX0;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=Propionate--CoA ligase {ECO:0008006|Google:ProtNLM};
GN ORFNames=MONBRDRAFT_13709 {ECO:0000313|EMBL:EDQ92772.1};
OS Monosiga brevicollis (Choanoflagellate).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Monosiga.
OX NCBI_TaxID=81824 {ECO:0000313|EMBL:EDQ92772.1, ECO:0000313|Proteomes:UP000001357};
RN [1] {ECO:0000313|EMBL:EDQ92772.1, ECO:0000313|Proteomes:UP000001357}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MX1 / ATCC 50154 {ECO:0000313|Proteomes:UP000001357};
RX PubMed=18273011; DOI=10.1038/nature06617;
RG JGI Sequencing;
RA King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J.,
RA Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D.,
RA Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M.,
RA Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S.,
RA Richter D.J., Salamov A., Bork P., Lim W.A., Manning G., Miller W.T.,
RA McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D.;
RT "The genome of the choanoflagellate Monosiga brevicollis and the origin of
RT metazoans.";
RL Nature 451:783-788(2008).
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
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DR EMBL; CH991543; EDQ92772.1; -; Genomic_DNA.
DR RefSeq; XP_001742534.1; XM_001742482.1.
DR AlphaFoldDB; A9UNX0; -.
DR STRING; 81824.A9UNX0; -.
DR EnsemblProtists; EDQ92772; EDQ92772; MONBRDRAFT_13709.
DR GeneID; 5887988; -.
DR KEGG; mbr:MONBRDRAFT_13709; -.
DR eggNOG; KOG1175; Eukaryota.
DR InParanoid; A9UNX0; -.
DR OMA; FIMGRTD; -.
DR Proteomes; UP000001357; Unassembled WGS sequence.
DR GO; GO:0050218; F:propionate-CoA ligase activity; IBA:GO_Central.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43347; ACYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR43347:SF3; ACYL-COA SYNTHETASE SHORT-CHAIN FAMILY MEMBER 3, MITOCHONDRIAL; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001357}.
FT DOMAIN 24..402
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 468..550
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EDQ92772.1"
SQ SEQUENCE 589 AA; 64246 MW; 1ABE8E3BB751323C CRC64;
NPAKPDWFKG WQLNVAHNCL DRHLPTRADQ PALLYESPAL GISQAITYAD LTDQVSRFAH
VLQERCEVTK GDRVIIYMPM CPEAIVAMLA CARLGAIHSV VFGGFASKEL ATRIDAAQPK
AVLSSTHGLD GVKAVNYKKL TDEAHRLCTF KPGIQHSDDH TATANLLRTG DLDWEDCMNT
AGHTKPVPID ATDPLYVLYT SGTTGKPKGV VREAGGHAVV LADTIQSIFN IHPGQVMFTP
SDIGWVVGHS YIVYAPLLAG ATGVLYEGKP TTTPDASAFW RIIEKHKVKA MFTAPTALRA
IKKEDPEGML VQQHDLSSLE TVFVAGKRAD PASVQWAEQV LQKPIVDNYW QTETGSPMSA
CSGHLPIKYG SCFKPVHGWD LQIVDDHGQT VPVGETGNLV AKLPLPPGAA TTLWKDHERY
DSSYLAAFPG YYQTGDAGFI DEDNYVHVLT RTDDVINTAG HRMSTGVLEG ALTAHDKVVE
AAVVGATDEL KGQLPVGFVV LKTGKSFESD HDLKQLRKEL VQRVREDVGP VAAFKRVYVV
RQLPKTRSGK TLRMVLRQMV DGQPLTLPPT IEDASIVDSV RQEIADQDA
//
