ID A9UNZ2_MONBE Unreviewed; 352 AA.
AC A9UNZ2;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 83.
DE RecName: Full=Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011};
DE Flags: Fragment;
GN ORFNames=MONBRDRAFT_13710 {ECO:0000313|EMBL:EDQ92328.1};
OS Monosiga brevicollis (Choanoflagellate).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Monosiga.
OX NCBI_TaxID=81824 {ECO:0000313|EMBL:EDQ92328.1, ECO:0000313|Proteomes:UP000001357};
RN [1] {ECO:0000313|EMBL:EDQ92328.1, ECO:0000313|Proteomes:UP000001357}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MX1 / ATCC 50154 {ECO:0000313|Proteomes:UP000001357};
RX PubMed=18273011; DOI=10.1038/nature06617;
RG JGI Sequencing;
RA King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J.,
RA Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D.,
RA Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M.,
RA Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S.,
RA Richter D.J., Salamov A., Bork P., Lim W.A., Manning G., Miller W.T.,
RA McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D.;
RT "The genome of the choanoflagellate Monosiga brevicollis and the origin of
RT metazoans.";
RL Nature 451:783-788(2008).
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DR EMBL; CH991543; EDQ92328.1; -; Genomic_DNA.
DR RefSeq; XP_001742090.1; XM_001742038.1.
DR AlphaFoldDB; A9UNZ2; -.
DR STRING; 81824.A9UNZ2; -.
DR EnsemblProtists; EDQ92328; EDQ92328; MONBRDRAFT_13710.
DR GeneID; 5887650; -.
DR KEGG; mbr:MONBRDRAFT_13710; -.
DR eggNOG; KOG4278; Eukaryota.
DR InParanoid; A9UNZ2; -.
DR OMA; QFQGCLC; -.
DR Proteomes; UP000001357; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0004713; F:protein tyrosine kinase activity; IBA:GO_Central.
DR CDD; cd00192; PTKc; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR PANTHER; PTHR24416:SF617; RECEPTOR PROTEIN-TYROSINE KINASE; 1.
DR PANTHER; PTHR24416; TYROSINE-PROTEIN KINASE RECEPTOR; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR PIRSF; PIRSF000654; Integrin-linked_kinase; 1.
DR PRINTS; PR00109; TYRKINASE.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Reference proteome {ECO:0000313|Proteomes:UP000001357}.
FT DOMAIN 77..332
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT BINDING 104
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EDQ92328.1"
FT NON_TER 352
FT /evidence="ECO:0000313|EMBL:EDQ92328.1"
SQ SEQUENCE 352 AA; 39758 MW; DFB8A4266C73C18D CRC64;
DVFAYIAVNK RMGTIHCHIY HVPKGSGNRA YAAINNAFKM LAADEKARGS NPFAVTDPKR
EAAPDLLFRH QIHRADLTAI QQIGAGQFGA VYIATHRILQ RAVKLLRNAA STADKDEFTR
EAETMLVLDH PNLVKMIGVA VQQKPWLCVL EYMKYGDLKS FLSTCREKKI PLRYGEMIYF
GEQLASGCGY LASQRMIHMD LAARNALVTD NNIVKVADFG LTRPMEPGVD YLLLREPMKL
ALKWMAPEGM DKKYFSEKSD VWSFGVMLWE IASYGANPYS QIKTQEIQLK VREGLRLSKP
PGCSDEFYDV MNTCWEQDPD NRPNFRLLEM RLSGIREANP TPSRDVGLVV SS
//
