ID   A9UPD6_MONBE            Unreviewed;      1555 AA.
AC   A9UPD6;
DT   05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   05-FEB-2008, sequence version 1.
DT   24-JAN-2024, entry version 60.
DE   RecName: Full=PKD domain-containing protein {ECO:0000259|PROSITE:PS50093};
GN   ORFNames=MONBRDRAFT_22044 {ECO:0000313|EMBL:EDQ92400.1};
OS   Monosiga brevicollis (Choanoflagellate).
OC   Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Monosiga.
OX   NCBI_TaxID=81824 {ECO:0000313|EMBL:EDQ92400.1, ECO:0000313|Proteomes:UP000001357};
RN   [1] {ECO:0000313|EMBL:EDQ92400.1, ECO:0000313|Proteomes:UP000001357}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MX1 / ATCC 50154 {ECO:0000313|Proteomes:UP000001357};
RX   PubMed=18273011; DOI=10.1038/nature06617;
RG   JGI Sequencing;
RA   King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J.,
RA   Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D.,
RA   Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M.,
RA   Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S.,
RA   Richter D.J., Salamov A., Bork P., Lim W.A., Manning G., Miller W.T.,
RA   McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D.;
RT   "The genome of the choanoflagellate Monosiga brevicollis and the origin of
RT   metazoans.";
RL   Nature 451:783-788(2008).
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DR   EMBL; CH991543; EDQ92400.1; -; Genomic_DNA.
DR   RefSeq; XP_001742162.1; XM_001742110.1.
DR   STRING; 81824.A9UPD6; -.
DR   EnsemblProtists; EDQ92400; EDQ92400; MONBRDRAFT_22044.
DR   GeneID; 5888157; -.
DR   KEGG; mbr:MONBRDRAFT_22044; -.
DR   eggNOG; ENOG502QQKP; Eukaryota.
DR   InParanoid; A9UPD6; -.
DR   Proteomes; UP000001357; Unassembled WGS sequence.
DR   CDD; cd00146; PKD; 1.
DR   Gene3D; 2.60.120.200; -; 2.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   Gene3D; 2.120.10.30; TolB, C-terminal domain; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR012938; Glc/Sorbosone_DH.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR022409; PKD/Chitinase_dom.
DR   InterPro; IPR000601; PKD_dom.
DR   InterPro; IPR035986; PKD_dom_sf.
DR   InterPro; IPR011041; Quinoprot_gluc/sorb_DH.
DR   PANTHER; PTHR19328; HEDGEHOG-INTERACTING PROTEIN; 1.
DR   PANTHER; PTHR19328:SF13; HIPL1 PROTEIN; 1.
DR   Pfam; PF07995; GSDH; 1.
DR   Pfam; PF18911; PKD_4; 1.
DR   SMART; SM00089; PKD; 1.
DR   SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 3.
DR   SUPFAM; SSF49299; PKD domain; 1.
DR   SUPFAM; SSF50952; Soluble quinoprotein glucose dehydrogenase; 1.
DR   PROSITE; PS50093; PKD; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001357};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..1555
FT                   /note="PKD domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5002744347"
FT   DOMAIN          388..468
FT                   /note="PKD"
FT                   /evidence="ECO:0000259|PROSITE:PS50093"
FT   REGION          970..1011
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1555 AA;  165337 MW;  985B8D54E907820C CRC64;
     MRGLALGLAC LATLACVLAL PAGFNDEVIL NVNEVMSIVN LDDHRILAAK RDGNILIVDW
     STKPAQTASY LVLPVDSYGE RGCMSIILDP DFATNNYFYV YYSSIPGGGF RVSRFEHSNN
     NGGTSSRADQ NSEVLIWDDP DGYIGPYHYG GDISFGPDEH IYISLGDKYY AQLAQDMSYT
     AGKVIRVSKT GAFPSDNLGL DDGVGGIHDG IWAVGMRNGY RSRWDLATNR YFIAEVGGNN
     QAVAQEDIHL GAARKNFGWP LCEGACDSPD FAYTCNCNDY DDPIFHYTHT DSNAPTGSNA
     AIVGGFVNWG SHLPQEYYGA YFFADYSRGW MKYLKFEADG KTVASENMFD NYMTSVINFE
     PALDGSFFYS TLNQIRHITY SSGNQYPVIY SAWADPATGS APLSVTFDVS AFDEDGDALT
     YTWTLGNGQV LTGKSVSTTY YSEGTYTAYV TVADAEHQVV SDDIKIEVGI PPVVNILSPS
     PSMKFVANQV LEFDCQGQSG STGAYLPNSA HTWGMILLHD DHTHPAVNDH VGSTMTFTIP
     SEGHGFMASV GYRATCTVEH NGLIASKSIE LWPDEVYITI ATQPVDLGIF FDGIASNAPF
     TTDTMIGFYH LISAQESVCK DGVLYRFASW SHVSGNEHTI TVPGQDTTYT ASYYTDGSCI
     DEVPVSNGLV MHLKGDEGVV TDSSGYISEW QDLSGSNNLS PPAGASAPLL LAGQLNGHSV
     VTFDGDTEAL GADSASGLPL GNSARTVFVV VKYDSPGWGG FSWGESGCKN VFGLTVGAGQ
     GYLFIEDYCG SPSAEMGNGE DWMIHSAVYD GSTLEHMRDG EVIETLSGGS TGYGTADTMI
     RLGVEINDGV NVKAQYAEVI VFNRALSSSE MDSVHEYLHL KYFDEGNTIE EVKLTFSTSP
     VGVPVTIEGH EQASPALIET QPGAPVQVSV PQSYCQGNTL FAFDQWTISS SPSFELLAPG
     VDTTYTASFT PTGSCGTTTT TTTQGPSSTT SAETTTTTTT TSPSTGNNEP PVTAGLVMRL
     NSQQGLVAAG NGDVSTWEDQ TGNGNDLQSL VGTGKPTVVS GQLNGHGVVS FDGSDDALGR
     DGVNNIPTGN ADRSLFLVVK YESAGWGGLS FGSVGCNAMY GATVTSSVGE LFVDTYCSGS
     AYASGTLGLD AGWLIQQVII KDQQLHHYKD NTLLETLDAS GLATTGAKIV MGAEHNLNSK
     VKMSVADVMV FDRAVSGSER QQLVAYLEAR YLSDATPVYS AVTFDSTPSG LDLVVDGEAQ
     ATPVTLTYLS GTEVTVEAPA VQCTDSDVKY TFGAWNSGYA QATQTFTVGD ADVSVIAAYS
     NTGSCSTGSD ELPVQLGLVM QLDADDITDV SGSGSVNVWP DAVHGNGLSV PASLSKPSLV
     VNGLNSKAFV SFDGAGNALG RDDIGALPSG SADRTIVMVV KYDSAGWGGF TYGSAGCLQA
     FGPAVSVNLG QLMVENYCTN DDVQSGVSGQ GAGWMVQTVV LKSNVMSHYK DQELIESYTL
     GYLTAADGHI RMGVEINDWS KLDMDVAAVA AWDRALESSE RQQVVDHFKS YYGLA
//