ID A9UQC3_MONBE Unreviewed; 497 AA.
AC A9UQC3;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE RecName: Full=Bromodomain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=MONBRDRAFT_13985 {ECO:0000313|EMBL:EDQ92572.1};
OS Monosiga brevicollis (Choanoflagellate).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Monosiga.
OX NCBI_TaxID=81824 {ECO:0000313|EMBL:EDQ92572.1, ECO:0000313|Proteomes:UP000001357};
RN [1] {ECO:0000313|EMBL:EDQ92572.1, ECO:0000313|Proteomes:UP000001357}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MX1 / ATCC 50154 {ECO:0000313|Proteomes:UP000001357};
RX PubMed=18273011; DOI=10.1038/nature06617;
RG JGI Sequencing;
RA King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J.,
RA Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D.,
RA Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M.,
RA Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S.,
RA Richter D.J., Salamov A., Bork P., Lim W.A., Manning G., Miller W.T.,
RA McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D.;
RT "The genome of the choanoflagellate Monosiga brevicollis and the origin of
RT metazoans.";
RL Nature 451:783-788(2008).
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DR EMBL; CH991543; EDQ92572.1; -; Genomic_DNA.
DR RefSeq; XP_001742334.1; XM_001742282.1.
DR AlphaFoldDB; A9UQC3; -.
DR STRING; 81824.A9UQC3; -.
DR EnsemblProtists; EDQ92572; EDQ92572; MONBRDRAFT_13985.
DR GeneID; 5887915; -.
DR KEGG; mbr:MONBRDRAFT_13985; -.
DR eggNOG; KOG1474; Eukaryota.
DR InParanoid; A9UQC3; -.
DR OMA; SEDSETX; -.
DR Proteomes; UP000001357; Unassembled WGS sequence.
DR GO; GO:0000785; C:chromatin; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0070577; F:lysine-acetylated histone binding; IBA:GO_Central.
DR GO; GO:0006338; P:chromatin remodeling; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IBA:GO_Central.
DR CDD; cd05498; Bromo_Brdt_II_like; 1.
DR Gene3D; 1.20.1270.220; -; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 2.
DR InterPro; IPR043509; Bromo_Brdt_II.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR027353; NET_dom.
DR InterPro; IPR038336; NET_sf.
DR PANTHER; PTHR22880:SF225; BROMODOMAIN-CONTAINING PROTEIN BET-1; 1.
DR PANTHER; PTHR22880; FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS; 1.
DR Pfam; PF17035; BET; 1.
DR Pfam; PF00439; Bromodomain; 2.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 2.
DR SUPFAM; SSF47370; Bromodomain; 2.
DR PROSITE; PS00633; BROMODOMAIN_1; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 2.
DR PROSITE; PS51525; NET; 1.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW Reference proteome {ECO:0000313|Proteomes:UP000001357};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 98..170
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT DOMAIN 261..333
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT DOMAIN 418..497
FT /note="NET"
FT /evidence="ECO:0000259|PROSITE:PS51525"
FT REGION 1..81
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 353..424
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 42..56
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 370..384
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 385..399
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 497 AA; 53975 MW; 35A10254A1CDD4AA CRC64;
MADAAGENNG VDEDRDNKPE SVASPAPAPS ATAALLAAAS TDDGTASPQG SATPGPGTPS
VIMAPGTPDS GSAGGTPRTG RMTNQLQYIS KVILPTLNKH PSAWPFKKPV DWKKLGLLSY
PEIIANPMDL GTIRNKLRKK EYFSGRECLD DIELVWHNCQ TFNRPSDDVY IMSQALESDY
KQMLANLPEP EVPLDRPSAK AKSAQAIKAA PALIVPSLPT HRRQSSRVIR APKDGLLAAS
SRLPAHMRVC YDIIKDLFGK KHQAYAWPFY EPVDIVKLNI PDYYDVIKQP MDLGTVRTKL
EEGEYETRDD FAHDVRLVFA NCYTYNPPGS DVVKMAKSTS EVFELQWAAL DAPAPATPAP
TSAKSSSKPA PKKPAKKRAK APPKKAPPKS TPAPAPAPAT TAVPTTLHHH DDDDEDGHSS
GDEAQLPMTW DEKKILSQNI NLLPSDCVPE IVNIVQSHEP NVGGDANDEF ELDFDKLSTR
TLRALDRYVR SNLPASG
//
