ID A9URL7_MONBE Unreviewed; 705 AA.
AC A9URL7;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 24-JAN-2024, entry version 70.
DE RecName: Full=SH3 domain-containing protein {ECO:0000259|PROSITE:PS50002};
GN ORFNames=MONBRDRAFT_6110 {ECO:0000313|EMBL:EDQ91946.1};
OS Monosiga brevicollis (Choanoflagellate).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Monosiga.
OX NCBI_TaxID=81824 {ECO:0000313|EMBL:EDQ91946.1, ECO:0000313|Proteomes:UP000001357};
RN [1] {ECO:0000313|EMBL:EDQ91946.1, ECO:0000313|Proteomes:UP000001357}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MX1 / ATCC 50154 {ECO:0000313|Proteomes:UP000001357};
RX PubMed=18273011; DOI=10.1038/nature06617;
RG JGI Sequencing;
RA King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J.,
RA Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D.,
RA Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M.,
RA Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S.,
RA Richter D.J., Salamov A., Bork P., Lim W.A., Manning G., Miller W.T.,
RA McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D.;
RT "The genome of the choanoflagellate Monosiga brevicollis and the origin of
RT metazoans.";
RL Nature 451:783-788(2008).
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DR EMBL; CH991544; EDQ91946.1; -; Genomic_DNA.
DR RefSeq; XP_001743232.1; XM_001743180.1.
DR AlphaFoldDB; A9URL7; -.
DR STRING; 81824.A9URL7; -.
DR EnsemblProtists; EDQ91946; EDQ91946; MONBRDRAFT_6110.
DR GeneID; 5888434; -.
DR KEGG; mbr:MONBRDRAFT_6110; -.
DR eggNOG; KOG1130; Eukaryota.
DR InParanoid; A9URL7; -.
DR Proteomes; UP000001357; Unassembled WGS sequence.
DR GO; GO:0005938; C:cell cortex; IBA:GO_Central.
DR GO; GO:0001965; F:G-protein alpha-subunit binding; IBA:GO_Central.
DR GO; GO:0005092; F:GDP-dissociation inhibitor activity; IBA:GO_Central.
DR GO; GO:0000132; P:establishment of mitotic spindle orientation; IBA:GO_Central.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR45954; LD33695P; 1.
DR PANTHER; PTHR45954:SF1; LD33695P; 1.
DR Pfam; PF14604; SH3_9; 1.
DR Pfam; PF13424; TPR_12; 1.
DR Pfam; PF13181; TPR_8; 1.
DR SMART; SM00326; SH3; 1.
DR SMART; SM00028; TPR; 6.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50002; SH3; 1.
DR PROSITE; PS50005; TPR; 5.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001357};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}; TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT REPEAT 12..45
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 91..124
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 163..196
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 203..236
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 243..276
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DOMAIN 638..699
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 287..315
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 370..421
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 527..575
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 587..633
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 377..415
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 705 AA; 75847 MW; 695899EDD8E8C309 CRC64;
MATNSRKKPE SFEEFVRAGA QFSKRRDFKR ALQCFSKALK LTTGVDLQKV SAVHVEAGSC
CYMLRQYEKA LYHYKRQLAA AKQSGRGADQ AHAYANIGVA LQALDLYDKA LECFKKQHAL
AQREGDAFLQ AQALDSIGAC IDVSSPHHVF PVVWQEEDVV AQAGYMSRLG VCHREQGRYT
EAIALFESVL ALHEARGDRR GQAQAHRHLG SVYEAFADFE KSAQHFESYI TLMRDLGDTA
MLFTGYDRLG TIYERLSDRR QAAENYKAAM SLAMEAGNQV YKAAARRHLH RATDQTSSAA
AAPAEEGDPG KRRMTVTLRA KKGMTKLFRN SFRRSQAIDS DVWLSEMERG HGGLATASLD
DVGDMVLEEE PDARSRRATS SGTNARGTGL DKSSERRNTV SALQADGTSS PVVHGSKKEK
SGLRGVLKLG SKRYNQEAES SADEGSANGG SLLVTTDIDA LDLDGEPAPS SGATGSEWAP
VLAAPSQFAA VDEPVELESV SVTTSEAASL GDSVETSLSY ISVDANTGAS KSAPRTPPLA
RAAGHRSTSF AAAGPRGAAP MAGPVGTAGP PTRSSHTLQF NAIRLEPNLA PETSTKPVET
SLVRSAPPPV APKPTLHAPA GQALATPDSP STKRAWIGAD QRWVAKYTHK SKEADNLSFK
KGDVLVNLKA VSDDWFFGKN VRTTQSGLIP ANYIEEEVTD DTAEA
//
