ID   A9USM4_MONBE            Unreviewed;       247 AA.
AC   A9USM4;
DT   05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   05-FEB-2008, sequence version 1.
DT   27-MAR-2024, entry version 57.
DE   RecName: Full=GDT1 family protein {ECO:0000256|RuleBase:RU365102};
GN   ORFNames=MONBRDRAFT_14366 {ECO:0000313|EMBL:EDQ92127.1};
OS   Monosiga brevicollis (Choanoflagellate).
OC   Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Monosiga.
OX   NCBI_TaxID=81824 {ECO:0000313|EMBL:EDQ92127.1, ECO:0000313|Proteomes:UP000001357};
RN   [1] {ECO:0000313|EMBL:EDQ92127.1, ECO:0000313|Proteomes:UP000001357}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MX1 / ATCC 50154 {ECO:0000313|Proteomes:UP000001357};
RX   PubMed=18273011; DOI=10.1038/nature06617;
RG   JGI Sequencing;
RA   King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J.,
RA   Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D.,
RA   Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M.,
RA   Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S.,
RA   Richter D.J., Salamov A., Bork P., Lim W.A., Manning G., Miller W.T.,
RA   McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D.;
RT   "The genome of the choanoflagellate Monosiga brevicollis and the origin of
RT   metazoans.";
RL   Nature 451:783-788(2008).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC       ECO:0000256|RuleBase:RU365102}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU365102}.
CC   -!- SIMILARITY: Belongs to the GDT1 family. {ECO:0000256|ARBA:ARBA00009190,
CC       ECO:0000256|RuleBase:RU365102}.
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DR   EMBL; CH991544; EDQ92127.1; -; Genomic_DNA.
DR   RefSeq; XP_001743413.1; XM_001743361.1.
DR   AlphaFoldDB; A9USM4; -.
DR   STRING; 81824.A9USM4; -.
DR   EnsemblProtists; EDQ92127; EDQ92127; MONBRDRAFT_14366.
DR   GeneID; 5888678; -.
DR   KEGG; mbr:MONBRDRAFT_14366; -.
DR   eggNOG; KOG2881; Eukaryota.
DR   InParanoid; A9USM4; -.
DR   OMA; HRKDYSH; -.
DR   Proteomes; UP000001357; Unassembled WGS sequence.
DR   GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015085; F:calcium ion transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0005384; F:manganese ion transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; IBA:GO_Central.
DR   GO; GO:0032468; P:Golgi calcium ion homeostasis; IBA:GO_Central.
DR   GO; GO:0032472; P:Golgi calcium ion transport; IBA:GO_Central.
DR   GO; GO:0071421; P:manganese ion transmembrane transport; IBA:GO_Central.
DR   InterPro; IPR001727; GDT1-like.
DR   InterPro; IPR049555; GDT1-like_CS.
DR   PANTHER; PTHR12608:SF1; TRANSMEMBRANE PROTEIN 165; 1.
DR   PANTHER; PTHR12608; TRANSMEMBRANE PROTEIN HTP-1 RELATED; 1.
DR   Pfam; PF01169; UPF0016; 2.
DR   PROSITE; PS01214; UPF0016; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU365102};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001357};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU365102};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU365102}.
FT   TRANSMEM        49..73
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU365102"
FT   TRANSMEM        79..97
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU365102"
FT   TRANSMEM        135..157
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU365102"
FT   TRANSMEM        177..198
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU365102"
FT   TRANSMEM        210..228
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU365102"
SQ   SEQUENCE   247 AA;  26695 MW;  DA296656E0C036D4 CRC64;
     MNDALIRPSV QAASFTHAFI GGLSMMVVSE LGDKTFFIAA ILAMRHSRFT IFCGAIGALG
     LMTFLSAYVG ALATVIPRIY THYIATGLFV IFGLRLLRDG YNMADDEGAE ELEEVQQELK
     AKEEQLDGKC WSHSLHIHSA GLLSPVLVQS FIMTFLAEWG DRSQIATIIL GAREDPLGVT
     LGGILGHSIC TFIAVMGGRF MAQRISVRKV TIAGGVVFLI FALSGLFFED PSSEGMDAAV
     AEIELNN
//