ID A9UT79_MONBE Unreviewed; 442 AA.
AC A9UT79;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE RecName: Full=AAA+ ATPase domain-containing protein {ECO:0000259|SMART:SM00382};
DE Flags: Fragment;
GN ORFNames=MONBRDRAFT_340 {ECO:0000313|EMBL:EDQ91446.1};
OS Monosiga brevicollis (Choanoflagellate).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Monosiga.
OX NCBI_TaxID=81824 {ECO:0000313|EMBL:EDQ91446.1, ECO:0000313|Proteomes:UP000001357};
RN [1] {ECO:0000313|EMBL:EDQ91446.1, ECO:0000313|Proteomes:UP000001357}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MX1 / ATCC 50154 {ECO:0000313|Proteomes:UP000001357};
RX PubMed=18273011; DOI=10.1038/nature06617;
RG JGI Sequencing;
RA King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J.,
RA Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D.,
RA Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M.,
RA Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S.,
RA Richter D.J., Salamov A., Bork P., Lim W.A., Manning G., Miller W.T.,
RA McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D.;
RT "The genome of the choanoflagellate Monosiga brevicollis and the origin of
RT metazoans.";
RL Nature 451:783-788(2008).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: In the C-terminal section; belongs to the peptidase M41
CC family. {ECO:0000256|ARBA:ARBA00010044}.
CC -!- SIMILARITY: In the N-terminal section; belongs to the AAA ATPase
CC family. {ECO:0000256|ARBA:ARBA00010550}.
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DR EMBL; CH991545; EDQ91446.1; -; Genomic_DNA.
DR RefSeq; XP_001743868.1; XM_001743816.1.
DR AlphaFoldDB; A9UT79; -.
DR STRING; 81824.A9UT79; -.
DR MEROPS; M41.A10; -.
DR EnsemblProtists; EDQ91446; EDQ91446; MONBRDRAFT_340.
DR GeneID; 5889279; -.
DR KEGG; mbr:MONBRDRAFT_340; -.
DR eggNOG; KOG0731; Eukaryota.
DR InParanoid; A9UT79; -.
DR OMA; WLLPEQT; -.
DR Proteomes; UP000001357; Unassembled WGS sequence.
DR GO; GO:0005745; C:m-AAA complex; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.
DR GO; GO:0004222; F:metalloendopeptidase activity; IBA:GO_Central.
DR GO; GO:0034982; P:mitochondrial protein processing; IBA:GO_Central.
DR CDD; cd19501; RecA-like_FtsH; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.20.58.760; Peptidase M41; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041569; AAA_lid_3.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR005936; FtsH.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000642; Peptidase_M41.
DR InterPro; IPR037219; Peptidase_M41-like.
DR NCBIfam; TIGR01241; FtsH_fam; 1.
DR PANTHER; PTHR43655; ATP-DEPENDENT PROTEASE; 1.
DR PANTHER; PTHR43655:SF8; PARAPLEGIN; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF17862; AAA_lid_3; 1.
DR Pfam; PF01434; Peptidase_M41; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF140990; FtsH protease domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000001357}.
FT DOMAIN 34..174
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EDQ91446.1"
FT NON_TER 442
FT /evidence="ECO:0000313|EMBL:EDQ91446.1"
SQ SEQUENCE 442 AA; 48256 MW; 4ACBCA2A9AF2ABB3 CRC64;
FNDVAGLSEA KVELKEFVEF LKTPERFEKL GAKVPKGALL TGPPGTGKTL LAKAVAGEAQ
VPFFAVSGSD FVEMFVGVGP SRVRDLFKQA RGEAPCIIYI DEIDAIARAR GKSNGGRSNS
ERESTLNQLL VEMDGVDPST GCMVLASTNR VDIMDKALLR PGRFDRQISC DLPTLSERAE
IFGVHLRPLY LDCGNRAALQ DRMAALTPGM SGAQIASVCN EAALHAARLG RKAVVDADFD
YAVDRVSSGM ERRSRVISKE ERKIVAVHEC GHAIVGWYLQ HTDPVMKVSL VPRGQALGVT
QLLPNDHHLF SAEALKDRMA VLLGGRAAEK IFFDRITTGA QDDLQRVTRM AYSYVTQYGM
SKRMGPMTYR IPASGSEGKK GVADATAEQI DAEVAQLVES AFVRSLEQLQ KHRDKLDAMS
QSLLTKEILT YEDCVELLGP RP
//
