ID A9UTL6_MONBE Unreviewed; 280 AA.
AC A9UTL6;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 22-FEB-2023, entry version 46.
DE RecName: Full=IRS-type PTB domain-containing protein {ECO:0000259|Pfam:PF02174};
GN ORFNames=MONBRDRAFT_6358 {ECO:0000313|EMBL:EDQ91267.1};
OS Monosiga brevicollis (Choanoflagellate).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Monosiga.
OX NCBI_TaxID=81824 {ECO:0000313|EMBL:EDQ91267.1, ECO:0000313|Proteomes:UP000001357};
RN [1] {ECO:0000313|EMBL:EDQ91267.1, ECO:0000313|Proteomes:UP000001357}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MX1 / ATCC 50154 {ECO:0000313|Proteomes:UP000001357};
RX PubMed=18273011; DOI=10.1038/nature06617;
RG JGI Sequencing;
RA King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J.,
RA Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D.,
RA Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M.,
RA Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S.,
RA Richter D.J., Salamov A., Bork P., Lim W.A., Manning G., Miller W.T.,
RA McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D.;
RT "The genome of the choanoflagellate Monosiga brevicollis and the origin of
RT metazoans.";
RL Nature 451:783-788(2008).
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DR EMBL; CH991545; EDQ91267.1; -; Genomic_DNA.
DR RefSeq; XP_001743689.1; XM_001743637.1.
DR AlphaFoldDB; A9UTL6; -.
DR EnsemblProtists; EDQ91267; EDQ91267; MONBRDRAFT_6358.
DR GeneID; 5889277; -.
DR KEGG; mbr:MONBRDRAFT_6358; -.
DR InParanoid; A9UTL6; -.
DR Proteomes; UP000001357; Unassembled WGS sequence.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR002404; IRS_PTB.
DR InterPro; IPR011993; PH-like_dom_sf.
DR Pfam; PF02174; IRS; 1.
DR SMART; SM01244; IRS; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001357}.
FT DOMAIN 43..99
FT /note="IRS-type PTB"
FT /evidence="ECO:0000259|Pfam:PF02174"
FT REGION 109..136
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 220..269
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 110..124
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 220..266
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 280 AA; 30893 MW; 60C87277B44D899C CRC64;
MGNDGSKPWL DFDDHVEYSV VDLETKSNAI IAIAFPKFYF YKSKSDGFSC SLGDIRGYAQ
RNRVFSFETG RNCPGGPAKY TVRVKGRANI HQTMNDIIKD NMVEGPQQRF DPAEETEQRQ
QNLRRSMRRP PSSENTYDTL NTAVPMAGAA GSAPRSGSGE VYNTLQGSRS NSGAAATATA
PLGGNIYNHI ESMHPRSPVQ DYDHLQQPPT SVQENTYNVL NHSRSPHPSI SASPEYNSLS
SSHNSPPPGN LYNTLQATTT STAHLPDDYE QLEHYGFDAR
//
