ID   A9UXH2_MONBE            Unreviewed;       325 AA.
AC   A9UXH2;
DT   05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   05-FEB-2008, sequence version 1.
DT   27-MAR-2024, entry version 45.
DE   RecName: Full=CYRIA/CYRIB Rac1 binding domain-containing protein {ECO:0000259|Pfam:PF07159};
GN   ORFNames=MONBRDRAFT_35147 {ECO:0000313|EMBL:EDQ90006.1};
OS   Monosiga brevicollis (Choanoflagellate).
OC   Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Monosiga.
OX   NCBI_TaxID=81824 {ECO:0000313|EMBL:EDQ90006.1, ECO:0000313|Proteomes:UP000001357};
RN   [1] {ECO:0000313|EMBL:EDQ90006.1, ECO:0000313|Proteomes:UP000001357}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MX1 / ATCC 50154 {ECO:0000313|Proteomes:UP000001357};
RX   PubMed=18273011; DOI=10.1038/nature06617;
RG   JGI Sequencing;
RA   King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J.,
RA   Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D.,
RA   Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M.,
RA   Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S.,
RA   Richter D.J., Salamov A., Bork P., Lim W.A., Manning G., Miller W.T.,
RA   McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D.;
RT   "The genome of the choanoflagellate Monosiga brevicollis and the origin of
RT   metazoans.";
RL   Nature 451:783-788(2008).
CC   -!- SIMILARITY: Belongs to the CYRI family.
CC       {ECO:0000256|ARBA:ARBA00005778}.
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DR   EMBL; CH991549; EDQ90006.1; -; Genomic_DNA.
DR   RefSeq; XP_001745428.1; XM_001745376.1.
DR   AlphaFoldDB; A9UXH2; -.
DR   EnsemblProtists; EDQ90006; EDQ90006; MONBRDRAFT_35147.
DR   GeneID; 5890631; -.
DR   KEGG; mbr:MONBRDRAFT_35147; -.
DR   eggNOG; KOG3951; Eukaryota.
DR   InParanoid; A9UXH2; -.
DR   OMA; EYRSRFN; -.
DR   Proteomes; UP000001357; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0030833; P:regulation of actin filament polymerization; IEA:InterPro.
DR   InterPro; IPR039789; CYRI.
DR   InterPro; IPR009828; CYRIA/CYRIB_Rac1-bd.
DR   PANTHER; PTHR12422:SF1; GH09096P; 1.
DR   PANTHER; PTHR12422; UNCHARACTERIZED; 1.
DR   Pfam; PF07159; CYRIA-B_Rac1-bd; 1.
PE   3: Inferred from homology;
KW   Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001357}.
FT   DOMAIN          18..320
FT                   /note="CYRIA/CYRIB Rac1 binding"
FT                   /evidence="ECO:0000259|Pfam:PF07159"
SQ   SEQUENCE   325 AA;  36597 MW;  CE785E1A7F7A2F64 CRC64;
     MGNIVQVLRR DAQTLDKDIF VDFEKASPSD AELETYEKVN AVLSKADGIL KDLETYEGAG
     DPIRKAISNG SDEELQKQAW DAVSPLVALL KDFYIFSSEV ESVLPFLLEA LCTEAPATEA
     LEGKQALAKQ FAEILQFVLK FDDLKMNNPA VQNDFSYYRR TISRMKMKNP GEEEEAVVSN
     EEANRMSLFY AYPTPMLKTV SDATTKFVSE NHEIPVENTT DFLATLATIC RVMIESPDIY
     SRFEKPDTVT FCQRVMVGAI ILYDHVHLVG AFSKKNQSID IRASLKALKM HENPHLENLL
     NALRFSTKHL SDDSTPKDIK KLLNV
//