ID   A9V0G8_MONBE            Unreviewed;       760 AA.
AC   A9V0G8;
DT   05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   05-FEB-2008, sequence version 1.
DT   24-JAN-2024, entry version 48.
DE   RecName: Full=Dynein regulatory complex protein 1 {ECO:0008006|Google:ProtNLM};
GN   ORFNames=MONBRDRAFT_32581 {ECO:0000313|EMBL:EDQ89153.1};
OS   Monosiga brevicollis (Choanoflagellate).
OC   Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Monosiga.
OX   NCBI_TaxID=81824 {ECO:0000313|EMBL:EDQ89153.1, ECO:0000313|Proteomes:UP000001357};
RN   [1] {ECO:0000313|EMBL:EDQ89153.1, ECO:0000313|Proteomes:UP000001357}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MX1 / ATCC 50154 {ECO:0000313|Proteomes:UP000001357};
RX   PubMed=18273011; DOI=10.1038/nature06617;
RG   JGI Sequencing;
RA   King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J.,
RA   Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D.,
RA   Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M.,
RA   Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S.,
RA   Richter D.J., Salamov A., Bork P., Lim W.A., Manning G., Miller W.T.,
RA   McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D.;
RT   "The genome of the choanoflagellate Monosiga brevicollis and the origin of
RT   metazoans.";
RL   Nature 451:783-788(2008).
CC   -!- SIMILARITY: Belongs to the DRC1 family.
CC       {ECO:0000256|ARBA:ARBA00009688}.
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DR   EMBL; CH991552; EDQ89153.1; -; Genomic_DNA.
DR   RefSeq; XP_001746258.1; XM_001746206.1.
DR   AlphaFoldDB; A9V0G8; -.
DR   STRING; 81824.A9V0G8; -.
DR   EnsemblProtists; EDQ89153; EDQ89153; MONBRDRAFT_32581.
DR   GeneID; 5891526; -.
DR   KEGG; mbr:MONBRDRAFT_32581; -.
DR   eggNOG; ENOG502QQ2B; Eukaryota.
DR   InParanoid; A9V0G8; -.
DR   OMA; MPQELHN; -.
DR   Proteomes; UP000001357; Unassembled WGS sequence.
DR   GO; GO:0005858; C:axonemal dynein complex; IEA:InterPro.
DR   GO; GO:0005930; C:axoneme; IBA:GO_Central.
DR   GO; GO:0070286; P:axonemal dynein complex assembly; IBA:GO_Central.
DR   GO; GO:0060285; P:cilium-dependent cell motility; IBA:GO_Central.
DR   GO; GO:0003352; P:regulation of cilium movement; IBA:GO_Central.
DR   InterPro; IPR039505; DRC1/2_N.
DR   InterPro; IPR039750; DRC1/DRC2.
DR   InterPro; IPR029440; DRC1_C.
DR   PANTHER; PTHR21625:SF1; DYNEIN REGULATORY COMPLEX PROTEIN 1; 1.
DR   PANTHER; PTHR21625; NYD-SP28 PROTEIN; 1.
DR   Pfam; PF14772; NYD-SP28; 1.
DR   Pfam; PF14775; NYD-SP28_assoc; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001357}.
FT   DOMAIN          160..261
FT                   /note="Dynein regulatory complex protein 1/2 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14772"
FT   DOMAIN          666..725
FT                   /note="Dynein regulatory complex protein 1 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14775"
FT   REGION          1..92
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          605..624
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          276..422
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        1..32
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        49..63
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   760 AA;  85948 MW;  8F8A5BD54EE80CD2 CRC64;
     MASSADDAQS SGELGDNGSL EDFTTAGQGQ HADSDDVNGA APGEAASEVA ANTMTNEPAA
     AQSKTTPAED DVEEVKARSA LPPSVESEDP NERIRARRLR IAARREAERR AAAGIEDEPE
     EEESQINPEP VKSNIRITQG HQALDQLREQ GSDRVTLVRV TADFAESKRR RELAAARTER
     RQRLQEERDV TVTMYERIKK LMSESVVNKS VPELHETLQN QHAACRALID RKDQLISEFS
     GQLKAKDDEY VRLLRAQTAD VDSMLTYLDE EIQTLAANYH QQLEEIEEAF MAERQELLDA
     TRQEWQSTVD ARRDRELAYL QRATERVEEQ ERQLEHLRVT DLEEYSIIKG KLEQDIMQLQ
     QQLQAMKATY QLNTEKLEYN YAVLKKREEE NAITISQQKR QLNKLTDVLN SLQTKIAKQE
     HVIEQDNVKL TSEYTRAVQH FEDLQKKVRQ FTAADRHRID EVWDMNEEAL SELAKQLLAA
     DQAIHEQQLG VQWVRPLEVV FDSTASEQQV RSRAASAIAR ELLEGHEVDD LASGHLSTDT
     MRRALALLCE EGDFLLEPNF DDLLQDLEPT HRNLLRLDAM FKALNVHTEE DMKQLATYFI
     ASDQDQAAGD EEESDGHSKT QQDRLRLIPA VEVVPALRAF VEARHAAKGA AGTLGPSTAT
     LSRNEKFWER LADIVPPEHE RNYGALRDAL ERYHQMLTDR AQGIDDVDHL KQQNGELRML
     LKQYMTSDAN KSLVVPPTAV LAHQLQQGQQ AATAAAANAK
//