ID A9V1U6_MONBE Unreviewed; 522 AA.
AC A9V1U6;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=Dynein regulatory complex subunit 3 {ECO:0000256|ARBA:ARBA00040950};
GN ORFNames=MONBRDRAFT_37452 {ECO:0000313|EMBL:EDQ88625.1};
OS Monosiga brevicollis (Choanoflagellate).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Monosiga.
OX NCBI_TaxID=81824 {ECO:0000313|EMBL:EDQ88625.1, ECO:0000313|Proteomes:UP000001357};
RN [1] {ECO:0000313|EMBL:EDQ88625.1, ECO:0000313|Proteomes:UP000001357}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MX1 / ATCC 50154 {ECO:0000313|Proteomes:UP000001357};
RX PubMed=18273011; DOI=10.1038/nature06617;
RG JGI Sequencing;
RA King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J.,
RA Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D.,
RA Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M.,
RA Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S.,
RA Richter D.J., Salamov A., Bork P., Lim W.A., Manning G., Miller W.T.,
RA McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D.;
RT "The genome of the choanoflagellate Monosiga brevicollis and the origin of
RT metazoans.";
RL Nature 451:783-788(2008).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, flagellum axoneme
CC {ECO:0000256|ARBA:ARBA00004611}.
CC -!- SIMILARITY: Belongs to the DRC3 family.
CC {ECO:0000256|ARBA:ARBA00038378}.
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DR EMBL; CH991554; EDQ88625.1; -; Genomic_DNA.
DR RefSeq; XP_001746729.1; XM_001746677.1.
DR AlphaFoldDB; A9V1U6; -.
DR STRING; 81824.A9V1U6; -.
DR EnsemblProtists; EDQ88625; EDQ88625; MONBRDRAFT_37452.
DR GeneID; 5891830; -.
DR KEGG; mbr:MONBRDRAFT_37452; -.
DR eggNOG; KOG0531; Eukaryota.
DR InParanoid; A9V1U6; -.
DR OMA; RMICLIS; -.
DR Proteomes; UP000001357; Unassembled WGS sequence.
DR GO; GO:0005929; C:cilium; IBA:GO_Central.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0031514; C:motile cilium; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR45973:SF12; DYNEIN REGULATORY COMPLEX SUBUNIT 3; 1.
DR PANTHER; PTHR45973; PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED; 1.
DR Pfam; PF14580; LRR_9; 1.
DR SMART; SM00365; LRR_SD22; 4.
DR SMART; SM00369; LRR_TYP; 4.
DR SUPFAM; SSF52075; Outer arm dynein light chain 1; 1.
DR PROSITE; PS51450; LRR; 3.
PE 3: Inferred from homology;
KW Cell projection {ECO:0000256|ARBA:ARBA00022846};
KW Cilium {ECO:0000256|ARBA:ARBA00022846};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Flagellum {ECO:0000256|ARBA:ARBA00022846};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Reference proteome {ECO:0000313|Proteomes:UP000001357};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
SQ SEQUENCE 522 AA; 59087 MW; F0AB58BA2762ADBF CRC64;
MAHVFGFGEK IAVINDELLH KAVTEQAPEA QKAYGQDVDA SEKDIVMLRL DLSKILKIDN
LWAFTNLRKL QLDNNLIETI ENLDSLVHLE WLDLSYNQIE RIEGLDKLTK LKDLSLHSNK
IQRLEGLDQL KHLEVLSVGQ NNLASLDDAP VLYLRRFRKL SCLNLAENPL CDDPRYESYC
IAMLPQLVFL DYRRVAAETR QSARIKYQDQ LEVVEKADAD QILAEEREEE AAAQRARLAK
ACVPGLSGSA FFSRMVDKDF ASLREVEGMD ELFETLEARL VTAIDTLVEF AVSESERRND
EEAEFREALQ DGIEAINDRD ARRLEEFIER KAEIISALAA SGSAVDMERA EVLRDDLGAL
KHQLMDAEID LVGQIEDMLG NFERAYVEMC SKVTEQAQST FTEVRQLIEE IETQVGDVAN
GHIDAIIKGE MELNALQLSP QAQEVLRDKL ALGSAMTTAH DNHIGEVDST EDAILAAVTE
ARTKLLEGIQ TNMDKRHRAR VAEIMRFHKY HLTDIERVLN DI
//
