ID   A9V2L9_MONBE            Unreviewed;       519 AA.
AC   A9V2L9;
DT   05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   05-FEB-2008, sequence version 1.
DT   24-JAN-2024, entry version 76.
DE   RecName: Full=F-BAR domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=MONBRDRAFT_26520 {ECO:0000313|EMBL:EDQ88281.1};
OS   Monosiga brevicollis (Choanoflagellate).
OC   Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Monosiga.
OX   NCBI_TaxID=81824 {ECO:0000313|EMBL:EDQ88281.1, ECO:0000313|Proteomes:UP000001357};
RN   [1] {ECO:0000313|EMBL:EDQ88281.1, ECO:0000313|Proteomes:UP000001357}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MX1 / ATCC 50154 {ECO:0000313|Proteomes:UP000001357};
RX   PubMed=18273011; DOI=10.1038/nature06617;
RG   JGI Sequencing;
RA   King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J.,
RA   Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D.,
RA   Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M.,
RA   Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S.,
RA   Richter D.J., Salamov A., Bork P., Lim W.A., Manning G., Miller W.T.,
RA   McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D.;
RT   "The genome of the choanoflagellate Monosiga brevicollis and the origin of
RT   metazoans.";
RL   Nature 451:783-788(2008).
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DR   EMBL; CH991555; EDQ88281.1; -; Genomic_DNA.
DR   RefSeq; XP_001746874.1; XM_001746822.1.
DR   AlphaFoldDB; A9V2L9; -.
DR   STRING; 81824.A9V2L9; -.
DR   EnsemblProtists; EDQ88281; EDQ88281; MONBRDRAFT_26520.
DR   GeneID; 5892262; -.
DR   KEGG; mbr:MONBRDRAFT_26520; -.
DR   eggNOG; KOG2856; Eukaryota.
DR   InParanoid; A9V2L9; -.
DR   OMA; EGGNTYN; -.
DR   Proteomes; UP000001357; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005768; C:endosome; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0005543; F:phospholipid binding; IBA:GO_Central.
DR   GO; GO:0007010; P:cytoskeleton organization; IBA:GO_Central.
DR   GO; GO:0097320; P:plasma membrane tubulation; IBA:GO_Central.
DR   GO; GO:0030100; P:regulation of endocytosis; IBA:GO_Central.
DR   CDD; cd07655; F-BAR_PACSIN; 1.
DR   Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR   Gene3D; 2.30.30.40; SH3 Domains; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR031160; F_BAR.
DR   InterPro; IPR001060; FCH_dom.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   PANTHER; PTHR23065; PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1; 1.
DR   PANTHER; PTHR23065:SF11; SYNDAPIN, ISOFORM C; 1.
DR   Pfam; PF00611; FCH; 1.
DR   Pfam; PF00018; SH3_1; 1.
DR   PRINTS; PR00452; SH3DOMAIN.
DR   SMART; SM00055; FCH; 1.
DR   SMART; SM00326; SH3; 1.
DR   SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR   SUPFAM; SSF50044; SH3-domain; 1.
DR   PROSITE; PS51741; F_BAR; 1.
DR   PROSITE; PS50002; SH3; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001357};
KW   SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW   ProRule:PRU00192}.
FT   DOMAIN          35..305
FT                   /note="F-BAR"
FT                   /evidence="ECO:0000259|PROSITE:PS51741"
FT   DOMAIN          400..462
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          356..388
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        366..385
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   519 AA;  58312 MW;  F8645D7A81F53C46 CRC64;
     MLQSQPTSIG SGPAAGPRLT PLHDVNAKIA RANKMASAPS FWKVNKYKRV VKRVEDGATL
     LDDLKALVHE RAQIERKYAQ MLAAFAKRWE DKIQRGPEEE EGTLRPAWLG LLSEATQLSE
     THDKNDERLR TEVADHIADW KKANYKKHMR THKTANDQFV KAQKPWAKLL REMKRSRKAY
     YASCEALTAA EDKARGLRRE GAASEDIAKA EAKVAKLTQL KADNRAQYQN NVTALAGDQQ
     RYETTMSKAF EFCQDLEQRR QDAFKGFMNT YGRILAGHTP AQCEPLLRDV QAVNPDADLL
     AYHKDKGSGM PFPRPVFEDY GAKPTIELVV NKVEDRNSVP LAMKLVDLPS KQCSRKSRRD
     NASFGSDEEE EEEDEEEEEE RDWQDDTQWE APPAAAAEEP ILPKMRALYA YQAEDEEELS
     LKPGDIIAQV EDEDEQGWCK GVHLGSGKTG IYPALYVEPL PEGADDGDYL EMVGTGVDGL
     SSTNVDPEES RRRRLKLYDN YENGTAVSPE APMVPDAVA
//