ID   A9V7W3_MONBE            Unreviewed;       329 AA.
AC   A9V7W3;
DT   05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   05-FEB-2008, sequence version 1.
DT   27-MAR-2024, entry version 54.
DE   RecName: Full=DEP domain-containing protein {ECO:0000259|PROSITE:PS50186};
GN   ORFNames=MONBRDRAFT_33845 {ECO:0000313|EMBL:EDQ86445.1};
OS   Monosiga brevicollis (Choanoflagellate).
OC   Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Monosiga.
OX   NCBI_TaxID=81824 {ECO:0000313|EMBL:EDQ86445.1, ECO:0000313|Proteomes:UP000001357};
RN   [1] {ECO:0000313|EMBL:EDQ86445.1, ECO:0000313|Proteomes:UP000001357}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MX1 / ATCC 50154 {ECO:0000313|Proteomes:UP000001357};
RX   PubMed=18273011; DOI=10.1038/nature06617;
RG   JGI Sequencing;
RA   King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J.,
RA   Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D.,
RA   Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M.,
RA   Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S.,
RA   Richter D.J., Salamov A., Bork P., Lim W.A., Manning G., Miller W.T.,
RA   McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D.;
RT   "The genome of the choanoflagellate Monosiga brevicollis and the origin of
RT   metazoans.";
RL   Nature 451:783-788(2008).
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DR   EMBL; CH991566; EDQ86445.1; -; Genomic_DNA.
DR   RefSeq; XP_001748835.1; XM_001748783.1.
DR   AlphaFoldDB; A9V7W3; -.
DR   STRING; 81824.A9V7W3; -.
DR   EnsemblProtists; EDQ86445; EDQ86445; MONBRDRAFT_33845.
DR   GeneID; 5894035; -.
DR   KEGG; mbr:MONBRDRAFT_33845; -.
DR   InParanoid; A9V7W3; -.
DR   OMA; MHIHASL; -.
DR   Proteomes; UP000001357; Unassembled WGS sequence.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd04371; DEP; 1.
DR   CDD; cd00173; SH2; 1.
DR   Gene3D; 3.30.505.10; SH2 domain; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR   InterPro; IPR000591; DEP_dom.
DR   InterPro; IPR036860; SH2_dom_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR22829; DEP DOMAIN PROTEIN; 1.
DR   PANTHER; PTHR22829:SF16; DH DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00610; DEP; 2.
DR   SMART; SM00049; DEP; 2.
DR   SUPFAM; SSF55550; SH2 domain; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 2.
DR   PROSITE; PS50186; DEP; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001357}.
FT   DOMAIN          64..122
FT                   /note="DEP"
FT                   /evidence="ECO:0000259|PROSITE:PS50186"
FT   DOMAIN          149..223
FT                   /note="DEP"
FT                   /evidence="ECO:0000259|PROSITE:PS50186"
SQ   SEQUENCE   329 AA;  37988 MW;  2CC84BF6CC40AA7A CRC64;
     MAASTVNRWT LMLRAADMDG FYDAADQLRS KLLQHALIKD RSYHLKVRTL PLACATAHLA
     VMKYPQCFKG NELVDYLVYS EECSTRAEAT MLGSSFIMFG VMHHVVDDHL FKDEGLFYRF
     RRDDDTFLAD KRSYRILIHK AMHIHASLHA SGIMIKDRDY GARTFRRCFI GRELVPWLIV
     QELCRDKEDA LALGSLLLQQ GFIRHVTDDH DFKEDYLFYR FCVDDLQAPD ALAGDEAGLR
     EVHMNIEGVR IDENFVLHGG VEEQVPEPPP RSLDFEQVLR NAYSMQMRAI KSLPWFHDVC
     SREEAERRLQ SFSCEDGAWL IRLSGEVCS
//