ID   A9V8B1_MONBE            Unreviewed;       787 AA.
AC   A9V8B1;
DT   05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   05-FEB-2008, sequence version 1.
DT   27-MAR-2024, entry version 75.
DE   RecName: Full=Bin3-type SAM domain-containing protein {ECO:0000259|PROSITE:PS51515};
GN   ORFNames=MONBRDRAFT_33899 {ECO:0000313|EMBL:EDQ86239.1};
OS   Monosiga brevicollis (Choanoflagellate).
OC   Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Monosiga.
OX   NCBI_TaxID=81824 {ECO:0000313|EMBL:EDQ86239.1, ECO:0000313|Proteomes:UP000001357};
RN   [1] {ECO:0000313|EMBL:EDQ86239.1, ECO:0000313|Proteomes:UP000001357}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MX1 / ATCC 50154 {ECO:0000313|Proteomes:UP000001357};
RX   PubMed=18273011; DOI=10.1038/nature06617;
RG   JGI Sequencing;
RA   King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J.,
RA   Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D.,
RA   Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M.,
RA   Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S.,
RA   Richter D.J., Salamov A., Bork P., Lim W.A., Manning G., Miller W.T.,
RA   McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D.;
RT   "The genome of the choanoflagellate Monosiga brevicollis and the origin of
RT   metazoans.";
RL   Nature 451:783-788(2008).
CC   -!- SIMILARITY: Belongs to the peptidase M24 family.
CC       {ECO:0000256|ARBA:ARBA00007319}.
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DR   EMBL; CH991567; EDQ86239.1; -; Genomic_DNA.
DR   RefSeq; XP_001748909.1; XM_001748857.1.
DR   AlphaFoldDB; A9V8B1; -.
DR   STRING; 81824.A9V8B1; -.
DR   EnsemblProtists; EDQ86239; EDQ86239; MONBRDRAFT_33899.
DR   GeneID; 5894139; -.
DR   KEGG; mbr:MONBRDRAFT_33899; -.
DR   eggNOG; KOG2776; Eukaryota.
DR   eggNOG; KOG2899; Eukaryota.
DR   InParanoid; A9V8B1; -.
DR   Proteomes; UP000001357; Unassembled WGS sequence.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:InterPro.
DR   CDD; cd02440; AdoMet_MTases; 2.
DR   Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR010675; Bin3_C.
DR   InterPro; IPR024160; BIN3_SAM-bd_dom.
DR   InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR   InterPro; IPR025714; Methyltranfer_dom.
DR   InterPro; IPR047113; PA2G4/ARX1.
DR   InterPro; IPR000994; Pept_M24.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR10804:SF11; PROLIFERATION-ASSOCIATED PROTEIN 2G4; 1.
DR   PANTHER; PTHR10804; PROTEASE FAMILY M24 METHIONYL AMINOPEPTIDASE, AMINOPEPTIDASE P; 1.
DR   Pfam; PF06859; Bin3; 1.
DR   Pfam; PF13847; Methyltransf_31; 1.
DR   Pfam; PF00557; Peptidase_M24; 1.
DR   SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   PROSITE; PS51515; BIN3_SAM; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001357};
KW   S-adenosyl-L-methionine {ECO:0000256|PROSITE-ProRule:PRU00848}.
FT   DOMAIN          25..350
FT                   /note="Bin3-type SAM"
FT                   /evidence="ECO:0000259|PROSITE:PS51515"
FT   REGION          152..202
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   787 AA;  87067 MW;  8951E6FC01654CD1 CRC64;
     MAWTCVWLCW IWVRLSGLFF PTVLGILLTA ADMRIVDWIQ GKRVLDVGCN TGQLAIQLAQ
     YMRPASVRGL DIDPVLISQA RHNLEVEASR FYGYFPKSLA LQRGALEPTP RRSDHVAAGF
     QERDCATLLQ TKQELDRLKR FYDEIESLGG TSRRFFGPPS PKRAATASNT PAHSPPSGSR
     GGPAGPSRHE LAEQARQLTE AAEKQQLQAA VVQNDQSFPR NVVFEAGDIL EAAATAAPRF
     HTILCLDVPK FVHLTHGDEG LRLLFAVQVE LLLPGGILVV QYQGWPSYTR DRNRTALYNY
     FMGRITLQPA AFAGWLNECH GLELVDEHVV IQGRATPPRV ALSLFLTPHT HTHTHTHTHT
     HSLSLCVGAR VCVREHFPVM EVVAADNEAP RAVYGVERET LNEDVLSKYR AAARICNETL
     QQLLPMCVPG ADISELSKAT DENLERLIAE LPASEGEDGE TMEKGIALPT CMAVNEIAGF
     HVQHAPGVLL AAGDVVKINF GVHVDGYIAQ IGHTHICGLG DQPMRGRRAD VVCAAYAASQ
     LVHRMLRPGV KSQQLTQAVH ELCRDFGCHA TEETFSCSIQ RFVHEGNKVF LNRLQVEDAP
     DGFEIEADDV FTIDIMVSNH SPKLRSGDIK PTVLIRNLAV EYQLKSRIAR HTYAEIARRF
     PTMWFAANRL ETEGAPLGIK ECVEHNLLVP YSVRTSKPGT QVAQFRFTAV VTPEHTLRLT
     SHPPPFVQST FGVRNEEQFQ LLSKVEPDEG VQVALPVNSA GYKPVDVDAL VLGESEDSSD
     VKMHDRV
//