ID A9VA18_MONBE Unreviewed; 589 AA.
AC A9VA18;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=Amino acid transporter transmembrane domain-containing protein {ECO:0000259|Pfam:PF01490};
GN ORFNames=MONBRDRAFT_34179 {ECO:0000313|EMBL:EDQ85587.1};
OS Monosiga brevicollis (Choanoflagellate).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Monosiga.
OX NCBI_TaxID=81824 {ECO:0000313|EMBL:EDQ85587.1, ECO:0000313|Proteomes:UP000001357};
RN [1] {ECO:0000313|EMBL:EDQ85587.1, ECO:0000313|Proteomes:UP000001357}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MX1 / ATCC 50154 {ECO:0000313|Proteomes:UP000001357};
RX PubMed=18273011; DOI=10.1038/nature06617;
RG JGI Sequencing;
RA King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J.,
RA Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D.,
RA Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M.,
RA Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S.,
RA Richter D.J., Salamov A., Bork P., Lim W.A., Manning G., Miller W.T.,
RA McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D.;
RT "The genome of the choanoflagellate Monosiga brevicollis and the origin of
RT metazoans.";
RL Nature 451:783-788(2008).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TMEM104 family.
CC {ECO:0000256|ARBA:ARBA00038166}.
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DR EMBL; CH991572; EDQ85587.1; -; Genomic_DNA.
DR RefSeq; XP_001749536.1; XM_001749484.1.
DR AlphaFoldDB; A9VA18; -.
DR EnsemblProtists; EDQ85587; EDQ85587; MONBRDRAFT_34179.
DR GeneID; 5894830; -.
DR KEGG; mbr:MONBRDRAFT_34179; -.
DR eggNOG; KOG3832; Eukaryota.
DR InParanoid; A9VA18; -.
DR OMA; RWLAFTI; -.
DR Proteomes; UP000001357; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR013057; AA_transpt_TM.
DR PANTHER; PTHR16189:SF0; TRANSMEMBRANE PROTEIN 104; 1.
DR PANTHER; PTHR16189; UNCHARACTERIZED; 1.
DR Pfam; PF01490; Aa_trans; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001357};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 45..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 144..163
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 202..221
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 233..251
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 271..288
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 309..332
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 352..374
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 395..415
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 421..445
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 465..487
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 17..458
FT /note="Amino acid transporter transmembrane"
FT /evidence="ECO:0000259|Pfam:PF01490"
SQ SEQUENCE 589 AA; 65139 MW; EC03B3DCE9639D7D CRC64;
MAGGGPDDGS TYAPLVAAVY VFNLIVGAGA LAMPKAFGES GYLGGSILIA ILAFTSYVTV
TYMIEAMAMA NCLMRTLKKN ASSRNNGLSI EGLSDETPLI NESVTPTERA NSADVAHFGD
YAITERAEMG SMAQHFFPPI GVKLFYFCII VYLYGDLCIY AVAVPKSLQS VTCPSHNSTM
INGTHVHHHE TCLGDLNSTG SYRIYLLLFA CLLGPFAFFN AQKTKWIQLM TTLLRWTTFM
MMIIIAIMGL AGTQTFNPPI ETPSPASVKV ATVEGLPGLF GVAIYSFMCH HSLPSMITPM
TTKRNVNGVL ISDFALILGF YCLLCFTAVF RFPGGTLEDL YTLNFKHFQS SFVSYFLGLF
PVFTLSANFP IIAITLRNNL ALLLAKPNGQ PRSPIIERVA YPLLAILPPF VVAFFTENVE
FLVGITGSYA GVGIQYVIPA CLVLFGRRRL ERELRERRNP HRSVFGGKIW IYGVLVWSVL
CIALVTFNHI YEGKTPDPDF VVSLLLCHKS RINCKLLCYE LSCHNIYIFL LRAQLHQFFQ
KVGSTKHFLH YDIKPRSKAP IPRCSITPAP ALALRRDPCH SENNIKAKC
//
