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Database: UniProt
Entry: A9VBU8_MONBE
LinkDB: A9VBU8_MONBE
Original site: A9VBU8_MONBE 
ID   A9VBU8_MONBE            Unreviewed;      2869 AA.
AC   A9VBU8;
DT   05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   05-FEB-2008, sequence version 1.
DT   07-NOV-2018, entry version 42.
DE   SubName: Full=Predicted protein {ECO:0000313|EMBL:EDQ84996.1};
GN   ORFNames=29689 {ECO:0000313|EMBL:EDQ84996.1};
OS   Monosiga brevicollis (Choanoflagellate).
OC   Eukaryota; Choanoflagellida; Craspedida; Salpingoecidae; Monosiga.
OX   NCBI_TaxID=81824 {ECO:0000313|Proteomes:UP000001357};
RN   [1] {ECO:0000313|EMBL:EDQ84996.1, ECO:0000313|Proteomes:UP000001357}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MX1 / ATCC 50154 {ECO:0000313|Proteomes:UP000001357};
RX   PubMed=18273011; DOI=10.1038/nature06617;
RG   JGI Sequencing;
RA   King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J.,
RA   Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D.,
RA   Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M.,
RA   Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S.,
RA   Richter D.J., Salamov A., Bork P., Lim W.A., Manning G., Miller W.T.,
RA   McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D.;
RT   "The genome of the choanoflagellate Monosiga brevicollis and the
RT   origin of metazoans.";
RL   Nature 451:783-788(2008).
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DR   EMBL; CH991578; EDQ84996.1; -; Genomic_DNA.
DR   RefSeq; XP_001750166.1; XM_001750114.1.
DR   ProteinModelPortal; A9VBU8; -.
DR   STRING; 431895.XP_001750166.1; -.
DR   EnsemblProtists; EDQ84996; EDQ84996; MONBRDRAFT_29689.
DR   GeneID; 5895420; -.
DR   KEGG; mbr:MONBRDRAFT_29689; -.
DR   eggNOG; KOG3533; Eukaryota.
DR   eggNOG; ENOG410XR97; LUCA.
DR   InParanoid; A9VBU8; -.
DR   OMA; DINIRTC; -.
DR   Proteomes; UP000001357; Unassembled WGS sequence.
DR   GO; GO:0030659; C:cytoplasmic vesicle membrane; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0005262; F:calcium channel activity; IEA:InterPro.
DR   GO; GO:0005509; F:calcium ion binding; IBA:GO_Central.
DR   GO; GO:0051209; P:release of sequestered calcium ion into cytosol; IBA:GO_Central.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR035910; RyR/IP3R_RIH_dom_sf.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   SUPFAM; SSF100909; SSF100909; 2.
DR   SUPFAM; SSF48371; SSF48371; 1.
DR   SUPFAM; SSF82109; SSF82109; 1.
DR   PROSITE; PS50919; MIR; 3.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001357};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001357};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    168    193       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2458   2475       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2495   2513       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2533   2554       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2587   2610       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2616   2637       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2644   2666       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2711   2735       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      303    353       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      422    488       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      495    544       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   COILED     2843   2863       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   2869 AA;  325290 MW;  EBE93B7AF365760E CRC64;
     MAAGVRIQAV SAEQGWGASC INAMLKRGCK ADCVHRTDLN KGKNSLSSPL TCGNYLPLSV
     EVVPLLFIPF SLSLSLSLSL SLSLSLCDFV NLSAQVQSLD SLLCFQGQEG PYFPNTTRHL
     DHPLQRGSRT TKASGPILAV LEKPKAKGSP RQRALREARL QPPSRPEVCV CVYVCVCVCV
     CVCVCVCVCV GFQRKKPQHQ HKDNILISHL SHGFCTLKPM ADRERAKTLT GVSEADLIGV
     QDHPFLSHGD FANLFFEGLH GYAFVDVLES HFLTVYQSTD QLPPSFEQSC VFQLLLSSDV
     EEGAVLKYGD TISLYHRATE QYVTRTKEHK GSGYAISLQP TRDETTLFRL LPRFKLRAIG
     DVIRYNDQLL LENTHSGQGT TYLSGTDVDN TGQSIVHAAG KRTTGIRMKL FAPFNVSSKA
     FEHVLKGGDY VRLHHSEANG FLVVAQNPQD VPGQFIGTEH TVCLRQLRDG SDAMDYHDAS
     SIWQVELKNT DRRGGRAVRW NDEIRLRNLL TNQYFNFEAK TKTNAMAPVE GPSNPHNLMQ
     LIETTQIASG GFAMNEPVRY HTFFYLSNST QRGWATVNTA TELVEEHSSG HGTDRQHFLR
     TMIQSVRQDQ DAFAFMDVSA ADIRNFYYAL GHVKKIEQLG VDLNEIEDHR ISRSLGEARV
     AIDKLIFFCT EDDDADDALE ADGHGETLHQ NMLLDLRVHH MLMGFLRMPF TRGEDGHLHW
     LPEWRTRIDS DTVVNDLARR AMRLLRQMCH DNVHTSNEIA HAYLADITDM SRLLSQVDAQ
     WNAADTLEEI FADNFELLSN LSDAYIQVYL RMLREAHTLA DLEQDLHLLS SLCIHDNIPI
     VNIQSMLRAA LLGESHVPVE QQLLPSTKLQ NGVIQIFARQ PTPNKPYEQW EGRWESLATY
     CKNHDSLRFY EAVLQLYNHL SIGKVADTTL REPEHVPFVE IMAILKANDL PVSLKRCYLT
     LCTNLYIADG DLLEDDGENR MWNDLGNERQ AAHRQKVIAN LLDFDELHTW IVSFLAANAQ
     QLLHVEHELH HDPHKKLSSE EKKLIDEEID LNEMGEALFH MIGTMIKLGY YVDSGRRQAI
     AHHLLAILMN SRLGINELTV HHGHGFEVMY RAKQAICNIF NASLKWDVSE HVSNLLKGFK
     QAYESKKGMH LEFTPRQLHN IVPHGDQALF WFARHNMTAE DFTNLILELT RYTHGGMRIA
     ALDLLMSSFN IRGMVLEALR YIEFVVDEAD QIMLEKLRET LLELGKEDHK DIHHVARHMT
     DEILWMTSQC INVNDVLGDP VTVNWRRPGS RLVPHHHHQE IFRHEGAHNL VFDIIKHHTE
     TAAQIQDLLE SPEVDELLKS CFDFLAFFVL KDKENQREFS DEHHVETILR CCAHGIHAEK
     MLGALLQSNS ELAEEHFAEQ GREEIGELID AFAENSRCQT PDFLSMLRAL ITESFAQNIQ
     TEIFNGLIKA LDAHKVLIDF GAETFGNVLG RNENVMSAIV TLYEKSDPTH EEEHLRELLV
     EFVHLLAMAG DGNAEIKDSI TRLIPYHEAM LPFLHIGSSS AKEKSHGIPR KTLVAFIAFV
     NLIYFPHLEA TDLDDEVPME AGGDFEMYGF DGDSATSKLL DLTRVCTSLK VQVEQLSVVM
     KRSWKVTVTD LDPFICDHVL PLFLHMTQHA VALLREVDPT QAVEFTTEAS ALRSVLVTYL
     NKRKKLSLSN PQFILAHDDR VSVAQALKDF AELINLNILS GVFGDESEQV KLIKVVRWYD
     DAEAKTMRLA TAAQNHGSHG SHGSRGTRKH GSSKLSLLGG KKRGSGAHHT ANVGTGTARL
     AAAMQTNEAS EGDKIQMELP FFVELIKKGF QEGHRPHHYS WMHNLKEEFD FPEFWRLVGI
     IRKLLSGHHN GKGGDTVESD EKTEAGTAHH HGRSIVRRAV RVHAFIDIDI DQCLQRIITH
     FEHHEVDDYA SEDFAEEEQV VKEFLILLCG ILSTEDTHHH RHHSTKAEQQ LVDVKQVARH
     LNRLNLPEML LFLVAAHHRS TVEMAARLGV LLLRSTPKEN EIDMTKVKIQ SSLNDLSQRS
     FLRAIKSPVG RRALLAWQHR FEQHIHFLNK RVHEDPIRSL HRDQDQEDLE NDTVLELLKL
     IEAMLAGGYM DMQTIFRHQE GQKIDVLATL VDLAGAYAPL IRMRLQDGFS VQDIERDEAI
     GEVEKELRRE VNDVGVLQQD PLLLYLTYME YSDLEITDEN QPHEMNNFFT IDRNRDIALQ
     ITVDWAYLFQ IEEIEHEHGL SDFRQKAGSE IMLTAAQLHS LKMCQQLLHT MDSIDEDCEN
     AILELLRGLL EGRKAGDHAF DVLGSCLFPV GISSQYSLSL SADANVMMHN LSKHMAAAGS
     KHGLEEDDDS DIEDEVDDAD ATHYSDADVA YGYYIVIKLL IDGSRFHGER IRQKLTAWED
     RNHAGLRKTV GRIEFLRNDD IEALYFPLPA AVTASQNHPM VQTLKQEMIN STILLNPMQK
     IVGFFNQANS LLNVVERRDR YHESWWKLFL SEQRLVSLLA LFLTILLNVY IIFDLGNDFL
     KEAGKKPDVP LFVLDIVKIL HLVCAILMLA GYALNGLPVD VERYAELAPA MQLPIGQYAV
     QFIKQQLFWV HSSGAPFFVL YCALSLVGLI HDTRWYAFHI FDLALHVPVM FLVVRAVKSN
     LPRLLGTFAF TFLLIYAFAL IGLAAFMGEY GFADTSAICT PQHTFLDCLR DHVYYGFYSS
     PVFDGELGLG AFFYALIYFI LVVLIMSSIV SGLIIDSFAQ FREESENIAS ANANVCFVCS
     LTRDDLEDVS PSGFDGHIAF DHNVWNYCWF ILYAEHRERE GKELTSSELH VLQHWQRRRF
     ANIVPVQRAM CLAENKSLED QRADLVQSRL DAIEKELAAI LTENRKRAQ
//
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