ID A9VEM8_MONBE Unreviewed; 324 AA.
AC A9VEM8;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=EGF-like domain-containing protein {ECO:0000259|PROSITE:PS50026};
DE Flags: Fragment;
GN ORFNames=MONBRDRAFT_30672 {ECO:0000313|EMBL:EDQ84013.1};
OS Monosiga brevicollis (Choanoflagellate).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Monosiga.
OX NCBI_TaxID=81824 {ECO:0000313|EMBL:EDQ84013.1, ECO:0000313|Proteomes:UP000001357};
RN [1] {ECO:0000313|EMBL:EDQ84013.1, ECO:0000313|Proteomes:UP000001357}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MX1 / ATCC 50154 {ECO:0000313|Proteomes:UP000001357};
RX PubMed=18273011; DOI=10.1038/nature06617;
RG JGI Sequencing;
RA King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J.,
RA Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D.,
RA Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M.,
RA Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S.,
RA Richter D.J., Salamov A., Bork P., Lim W.A., Manning G., Miller W.T.,
RA McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D.;
RT "The genome of the choanoflagellate Monosiga brevicollis and the origin of
RT metazoans.";
RL Nature 451:783-788(2008).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; CH991718; EDQ84013.1; -; Genomic_DNA.
DR RefSeq; XP_001751175.1; XM_001751123.1.
DR AlphaFoldDB; A9VEM8; -.
DR STRING; 81824.A9VEM8; -.
DR EnsemblProtists; EDQ84013; EDQ84013; MONBRDRAFT_30672.
DR GeneID; 5896436; -.
DR KEGG; mbr:MONBRDRAFT_30672; -.
DR InParanoid; A9VEM8; -.
DR Proteomes; UP000001357; Unassembled WGS sequence.
DR CDD; cd00054; EGF_CA; 2.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR InterPro; IPR000742; EGF-like_dom.
DR PANTHER; PTHR24049; CRUMBS FAMILY MEMBER; 1.
DR PANTHER; PTHR24049:SF22; DROSOPHILA CRUMBS HOMOLOG; 1.
DR Pfam; PF00008; EGF; 2.
DR SMART; SM00181; EGF; 2.
DR SUPFAM; SSF57196; EGF/Laminin; 2.
DR PROSITE; PS00022; EGF_1; 2.
DR PROSITE; PS01186; EGF_2; 2.
DR PROSITE; PS50026; EGF_3; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Reference proteome {ECO:0000313|Proteomes:UP000001357};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..324
FT /note="EGF-like domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002743182"
FT DOMAIN 31..68
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 270..306
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT REGION 248..268
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 249..268
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 58..67
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 296..305
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT NON_TER 324
FT /evidence="ECO:0000313|EMBL:EDQ84013.1"
SQ SEQUENCE 324 AA; 34983 MW; 8256AB09B149D348 CRC64;
MRPFSTLGCL ALAGLLLFSA PQPATATYGS DNLFCAWYNP CQNGATCSSN LLGVVCTCPT
GYTGLYCQNE PETGRCVTKH IIDNFEACSY SNDDGTVSWT SDWQESDPEH GGPSSGLVRI
FDGDLALTGP ASGAGGPKIT RTVDLSNTQD ARIEVKFHFE GDVESGDQAA LYVRKGSHSF
KRIETFDVSW CGKSKTFIKT YDISAYADAV TTIKFRVESE LRPSNEWFVV DYVAVMYEKC
DAGATTRAPA TTRAPTTTTT TTTTRAPTTT PNPCDSHTCK NGGTCRISNG RAYCDCKDGY
SGSQCETRIT TTPTPTTKWD PCNS
//
