ID   A9WIX5_CHLAA            Unreviewed;      1150 AA.
AC   A9WIX5;
DT   05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   05-FEB-2008, sequence version 1.
DT   27-MAR-2024, entry version 75.
DE   SubName: Full=ATPase-like protein {ECO:0000313|EMBL:ABY36434.1};
GN   OrderedLocusNames=Caur_3246 {ECO:0000313|EMBL:ABY36434.1};
OS   Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl).
OC   Bacteria; Chloroflexota; Chloroflexia; Chloroflexales; Chloroflexineae;
OC   Chloroflexaceae; Chloroflexus.
OX   NCBI_TaxID=324602 {ECO:0000313|EMBL:ABY36434.1, ECO:0000313|Proteomes:UP000002008};
RN   [1] {ECO:0000313|Proteomes:UP000002008}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29366 / DSM 635 / J-10-fl
RC   {ECO:0000313|Proteomes:UP000002008};
RX   PubMed=21714912; DOI=10.1186/1471-2164-12-334;
RA   Tang K.H., Barry K., Chertkov O., Dalin E., Han C.S., Hauser L.J.,
RA   Honchak B.M., Karbach L.E., Land M.L., Lapidus A., Larimer F.W.,
RA   Mikhailova N., Pitluck S., Pierson B.K., Blankenship R.E.;
RT   "Complete genome sequence of the filamentous anoxygenic phototrophic
RT   bacterium Chloroflexus aurantiacus.";
RL   BMC Genomics 12:334-334(2011).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000909; ABY36434.1; -; Genomic_DNA.
DR   RefSeq; WP_012259087.1; NC_010175.1.
DR   RefSeq; YP_001636823.1; NC_010175.1.
DR   AlphaFoldDB; A9WIX5; -.
DR   STRING; 324602.Caur_3246; -.
DR   EnsemblBacteria; ABY36434; ABY36434; Caur_3246.
DR   KEGG; cau:Caur_3246; -.
DR   PATRIC; fig|324602.8.peg.3665; -.
DR   eggNOG; COG0457; Bacteria.
DR   eggNOG; COG2114; Bacteria.
DR   eggNOG; COG3899; Bacteria.
DR   HOGENOM; CLU_004435_4_0_0; -.
DR   InParanoid; A9WIX5; -.
DR   Proteomes; UP000002008; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0004016; F:adenylate cyclase activity; IBA:GO_Central.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 2.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 2.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR041664; AAA_16.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PANTHER; PTHR16305:SF28; ADENYLATE CYCLASE 10; 1.
DR   PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR   Pfam; PF13191; AAA_16; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 2.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   4: Predicted;
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002008}.
FT   DOMAIN          38..172
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
SQ   SEQUENCE   1150 AA;  128807 MW;  7041EAC5FB8155BC CRC64;
     MEQQTSSQLF RAYVPATLRD QLSAGLLRAG QIQTYQGTIL YTDLSGFTRL TATFSTLPDG
     AERLHGILTS YFEVMIATIV ANGGDVIHIA GDALTAWWPG MTDPAMAIHC GHALHNAIAA
     LNPIVTPNGP FTLEIRVGVS VGIVHLLLVG IPNQGIHPVL IGAPIDAASL AEQQAKPGEV
     QLLLPAFRPT RFCDYQPPPE TPILTWEHFL PPSFARRLRL NTLVAEYRRC VPVFAAFDLP
     EDPTALQPLV MQAQAIAMRW GGWLNEIEVG NKGAVMVFLF GAPVAHGDDT SRAVGCAVEL
     RDRGIIRKAG ITVGSVFVGE VGSRLRRVYT AQGEDMNLAA LLMEQAQPGD IVISGRVRQD
     TLGRYRTSPP QQRNVKGYSR SIPAAVVLAK HAFTDERPFS SLQASLPAYT ELIGRTQERQ
     MIDHILDVAR QEGQVLLIEG EAGIGKSSLI HHLSARWIEY GYQGFRGECR SGMQEQPLHL
     WRNILSELCD IDDSAPMQVR QARLHHIATT FSSARPQHIA ALAHLFKIDG FDYTTKSTDI
     SPLIVELLIS RLKHEPLLIV LEDIHWADTA SLILTQDVID ALLPQLPLLV VISYRPAPEH
     LASFTSHIRQ YPFTTHHVLD RLPVYERAML IQQLIGVKDV DHRLLHYLER YAAGQPLFIK
     EYVRLLLQKE LIAIENDTAR LLRPLPPMQL SSSALGIVQA HIDRMEERTR LTFKAAAVIG
     RSFPLRLLLH IHPAHITESE LREDIEALLR DQLIEMEMAE PEPVYRFIYG IAHEAAYTSL
     LFAQRRHLHQ AISNWYQSTY QQELAGQDAP LAVYDVVIDH SIRAELWPVA VEHCWQAALI
     CARRSLFHSA LRYIEQGAGL AGPIGRRIDL IGLRMLLNDR IGNHLYQEED FRLIQQLFNE
     QAQPAMQALA AVLYLHHVLV SGQFHLIDEQ MTYAQATVRQ GHHHAGFSRL LQACIWLINA
     QHLALKGQSN QALEILRRVN RLCALVPRQV STPQPLNDLI LPDIIIAQSY ELEGWIQFEL
     GAFQRATSRF QQAIKLARAA NDWIVENRAL IGLCHVTLFS SQYEMVEEQL PHALYVARAI
     GDRYGQVLGL RTQALLHAKR NDMRTARRLI WQAIAIANSS QIGILEIVLL NELEKMAIAM
     EQDPETDSAD
//