ID ACCR_AGRFC Reviewed; 258 AA.
AC P32104; O30540;
DT 01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1993, sequence version 1.
DT 27-MAR-2024, entry version 132.
DE RecName: Full=Transcriptional repressor AccR;
GN Name=accR; OrderedLocusNames=Atu6138; ORFNames=AGR_pTi_255;
OS Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens
OS (strain C58)).
OG Plasmid pTiC58.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Rhizobium/Agrobacterium group; Agrobacterium;
OC Agrobacterium tumefaciens complex.
OX NCBI_TaxID=176299;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=1731335; DOI=10.1073/pnas.89.2.643;
RA von Bodman S., Hayman G.T., Farrand S.K.;
RT "Opine catabolism and conjugal transfer of the nopaline Ti plasmid pTiC58
RT are coordinately regulated by a single repressor.";
RL Proc. Natl. Acad. Sci. U.S.A. 89:643-647(1992).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=9393724; DOI=10.1128/jb.179.23.7559-7572.1997;
RA Kim H., Farrand S.K.;
RT "Characterization of the acc operon from the nopaline-type Ti plasmid
RT pTiC58, which encodes utilization of agrocinopines A and B and
RT susceptibility to agrocin 84.";
RL J. Bacteriol. 179:7559-7572(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=11743193; DOI=10.1126/science.1066804;
RA Wood D.W., Setubal J.C., Kaul R., Monks D.E., Kitajima J.P., Okura V.K.,
RA Zhou Y., Chen L., Wood G.E., Almeida N.F. Jr., Woo L., Chen Y.,
RA Paulsen I.T., Eisen J.A., Karp P.D., Bovee D. Sr., Chapman P.,
RA Clendenning J., Deatherage G., Gillet W., Grant C., Kutyavin T., Levy R.,
RA Li M.-J., McClelland E., Palmieri A., Raymond C., Rouse G.,
RA Saenphimmachak C., Wu Z., Romero P., Gordon D., Zhang S., Yoo H., Tao Y.,
RA Biddle P., Jung M., Krespan W., Perry M., Gordon-Kamm B., Liao L., Kim S.,
RA Hendrick C., Zhao Z.-Y., Dolan M., Chumley F., Tingey S.V., Tomb J.-F.,
RA Gordon M.P., Olson M.V., Nester E.W.;
RT "The genome of the natural genetic engineer Agrobacterium tumefaciens
RT C58.";
RL Science 294:2317-2323(2001).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C58 / ATCC 33970;
RX PubMed=11743194; DOI=10.1126/science.1066803;
RA Goodner B., Hinkle G., Gattung S., Miller N., Blanchard M., Qurollo B.,
RA Goldman B.S., Cao Y., Askenazi M., Halling C., Mullin L., Houmiel K.,
RA Gordon J., Vaudin M., Iartchouk O., Epp A., Liu F., Wollam C., Allinger M.,
RA Doughty D., Scott C., Lappas C., Markelz B., Flanagan C., Crowell C.,
RA Gurson J., Lomo C., Sear C., Strub G., Cielo C., Slater S.;
RT "Genome sequence of the plant pathogen and biotechnology agent
RT Agrobacterium tumefaciens C58.";
RL Science 294:2323-2328(2001).
CC -!- FUNCTION: Represses opine catabolism and conjugal transfer of the
CC nopaline Ti plasmid pTiC58.
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DR EMBL; AF010180; AAC17196.1; -; Genomic_DNA.
DR EMBL; AE007871; AAK91102.1; -; Genomic_DNA.
DR PIR; AH3244; AH3244.
DR PIR; T03429; T03429.
DR RefSeq; NP_396661.3; NC_003065.3.
DR RefSeq; WP_010974787.1; NZ_AF010180.1.
DR AlphaFoldDB; P32104; -.
DR SMR; P32104; -.
DR EnsemblBacteria; AAK91102; AAK91102; Atu6138.
DR GeneID; 39477164; -.
DR KEGG; atu:Atu6138; -.
DR PATRIC; fig|176299.10.peg.5345; -.
DR HOGENOM; CLU_060699_3_1_5; -.
DR OrthoDB; 31600at2; -.
DR PhylomeDB; P32104; -.
DR BioCyc; AGRO:ATU6138-MONOMER; -.
DR PRO; PR:P32104; -.
DR Proteomes; UP000000813; Plasmid Ti.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR Gene3D; 3.40.50.1360; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR014036; DeoR_C.
DR InterPro; IPR001034; DeoR_HTH.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR InterPro; IPR018356; Tscrpt_reg_HTH_DeoR_CS.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30363:SF44; GLUCITOL OPERON REPRESSOR; 1.
DR PANTHER; PTHR30363; HTH-TYPE TRANSCRIPTIONAL REGULATOR SRLR-RELATED; 1.
DR Pfam; PF00455; DeoRC; 1.
DR Pfam; PF08220; HTH_DeoR; 1.
DR PRINTS; PR00037; HTHLACR.
DR SMART; SM01134; DeoRC; 1.
DR SMART; SM00420; HTH_DEOR; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00894; HTH_DEOR_1; 1.
DR PROSITE; PS51000; HTH_DEOR_2; 1.
PE 4: Predicted;
KW DNA-binding; Plasmid; Reference proteome; Repressor; Transcription;
KW Transcription regulation.
FT CHAIN 1..258
FT /note="Transcriptional repressor AccR"
FT /id="PRO_0000050240"
FT DOMAIN 6..61
FT /note="HTH deoR-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00349"
FT DNA_BIND 23..42
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00349"
SQ SEQUENCE 258 AA; 28076 MW; 7222E1E45DF83A3D CRC64;
MVFNSTQDRQ AKIVELLRDE QFLAIGRLTE HFQISVATAR RDLSELHEAG LLRRTHGGAV
SVTQVTQDKP NAARAVWNRA EKAAIAGVVA GMIVEGDTVL LDAGTTALEV AKKLADRRNL
TFISNGLDIV EELTRGEGKS IYSVGGEYTE TNRSFRGPLA EQFIRQFNVD KLILNAASID
VDRGLICTSS PVNASVARAM IEVSSRVIVV ADHSKFTKSS LSVTARIEDV GVIVTDSGTR
TIIETIPEKL RKKFVVAN
//
